Haigis KM - Search Results

1

Epigenetic and Oncogenic Inhibitors Cooperatively Drive Differentiation and Kill KRAS-Mutant Colorectal Cancers.

Loi P, Schade AE, Rodriguez CL, Krishnan A, Perurena N, Nguyen VTM, Xu Y, Watanabe M, Davis RA, Gardner A, Pilla NF, Mattioli K, Popow O, Gunduz N, Lannagan TRM, Fitzgerald S, Sicinska ET, Lin JR, Tan W, Brais LK, Haigis KM, Giannakis M, Ng K, Santagata S, Helin K, Sansom OJ, Cichowski K. Loi P, et al. Among authors: haigis km. Cancer Discov. 2024 Dec 2;14(12):2430-2449. doi: 10.1158/2159-8290.CD-23-0866. Cancer Discov. 2024. PMID: 39121480 Free PMC article.

2

ROS1 signaling regulates epithelial differentiation in the epididymis.

Jun HJ, Roy J, Smith TB, Wood LB, Lane K, Woolfenden S, Punko D, Bronson RT, Haigis KM, Breton S, Charest A. Jun HJ, et al. Among authors: haigis km. Endocrinology. 2014 Sep;155(9):3661-73. doi: 10.1210/en.2014-1341. Epub 2014 Jun 27. Endocrinology. 2014. PMID: 24971615 Free PMC article.

3

Proteomic analysis of pRb loss highlights a signature of decreased mitochondrial oxidative phosphorylation.

Nicolay BN, Danielian PS, Kottakis F, Lapek JD Jr, Sanidas I, Miles WO, Dehnad M, Tschöp K, Gierut JJ, Manning AL, Morris R, Haigis K, Bardeesy N, Lees JA, Haas W, Dyson NJ. Nicolay BN, et al. Genes Dev. 2015 Sep 1;29(17):1875-89. doi: 10.1101/gad.264127.115. Epub 2015 Aug 27. Genes Dev. 2015. PMID: 26314710 Free PMC article.

4

Activated k-ras, but not h-ras or N-ras, regulates brain neural stem cell proliferation in a raf/rb-dependent manner.

Bender RH, Haigis KM, Gutmann DH. Bender RH, et al. Among authors: haigis km. Stem Cells. 2015 Jun;33(6):1998-2010. doi: 10.1002/stem.1990. Stem Cells. 2015. PMID: 25788415 Free PMC article.

5

RasGRP1 opposes proliferative EGFR-SOS1-Ras signals and restricts intestinal epithelial cell growth.

Depeille P, Henricks LM, van de Ven RA, Lemmens E, Wang CY, Matli M, Werb Z, Haigis KM, Donner D, Warren R, Roose JP. Depeille P, et al. Among authors: haigis km. Nat Cell Biol. 2015 Jun;17(6):804-15. doi: 10.1038/ncb3175. Epub 2015 May 25. Nat Cell Biol. 2015. PMID: 26005835 Free PMC article.

6

Mutant N-RAS protects colorectal cancer cells from stress-induced apoptosis and contributes to cancer development and progression.

Wang Y, Velho S, Vakiani E, Peng S, Bass AJ, Chu GC, Gierut J, Bugni JM, Der CJ, Philips M, Solit DB, Haigis KM. Wang Y, et al. Among authors: haigis km. Cancer Discov. 2013 Mar;3(3):294-307. doi: 10.1158/2159-8290.CD-12-0198. Epub 2012 Dec 28. Cancer Discov. 2013. PMID: 23274911 Free PMC article.

7

Tissue-specificity in cancer: The rule, not the exception.

Haigis KM, Cichowski K, Elledge SJ. Haigis KM, et al. Science. 2019 Mar 15;363(6432):1150-1151. doi: 10.1126/science.aaw3472. Science. 2019. PMID: 30872507 No abstract available.

8

Tissue-Specific Oncogenic Activity of KRAS^A146T.

Poulin EJ, Bera AK, Lu J, Lin YJ, Strasser SD, Paulo JA, Huang TQ, Morales C, Yan W, Cook J, Nowak JA, Brubaker DK, Joughin BA, Johnson CW, DeStefanis RA, Ghazi PC, Gondi S, Wales TE, Iacob RE, Bogdanova L, Gierut JJ, Li Y, Engen JR, Perez-Mancera PA, Braun BS, Gygi SP, Lauffenburger DA, Westover KD, Haigis KM. Poulin EJ, et al. Among authors: haigis km. Cancer Discov. 2019 Jun;9(6):738-755. doi: 10.1158/2159-8290.CD-18-1220. Epub 2019 Apr 5. Cancer Discov. 2019. PMID: 30952657 Free PMC article.

9

Identification of Endogenous Adenomatous Polyposis Coli Interaction Partners and β-Catenin-Independent Targets by Proteomics.

Popow O, Paulo JA, Tatham MH, Volk MS, Rojas-Fernandez A, Loyer N, Newton IP, Januschke J, Haigis KM, Näthke I. Popow O, et al. Among authors: haigis km. Mol Cancer Res. 2019 Sep;17(9):1828-1841. doi: 10.1158/1541-7786.MCR-18-1154. Epub 2019 Jun 3. Mol Cancer Res. 2019. PMID: 31160382 Free PMC article.

10

Proteogenomic Network Analysis of Context-Specific KRAS Signaling in Mouse-to-Human Cross-Species Translation.

Brubaker DK, Paulo JA, Sheth S, Poulin EJ, Popow O, Joughin BA, Strasser SD, Starchenko A, Gygi SP, Lauffenburger DA, Haigis KM. Brubaker DK, et al. Among authors: haigis km. Cell Syst. 2019 Sep 25;9(3):258-270.e6. doi: 10.1016/j.cels.2019.07.006. Epub 2019 Sep 11. Cell Syst. 2019. PMID: 31521603 Free PMC article.

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