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Page 1
Epigenetic and Oncogenic Inhibitors Cooperatively Drive Differentiation and Kill KRAS-Mutant Colorectal Cancers.
Loi P, Schade AE, Rodriguez CL, Krishnan A, Perurena N, Nguyen VTM, Xu Y, Watanabe M, Davis RA, Gardner A, Pilla NF, Mattioli K, Popow O, Gunduz N, Lannagan TRM, Fitzgerald S, Sicinska ET, Lin JR, Tan W, Brais LK, Haigis KM, Giannakis M, Ng K, Santagata S, Helin K, Sansom OJ, Cichowski K. Loi P, et al. Among authors: nguyen vtm. Cancer Discov. 2024 Dec 2;14(12):2430-2449. doi: 10.1158/2159-8290.CD-23-0866. Cancer Discov. 2024. PMID: 39121480 Free PMC article.
AKT and EZH2 inhibitors kill TNBCs by hijacking mechanisms of involution.
Schade AE, Perurena N, Yang Y, Rodriguez CL, Krishnan A, Gardner A, Loi P, Xu Y, Nguyen VTM, Mastellone GM, Pilla NF, Watanabe M, Ota K, Davis RA, Mattioli K, Xiang D, Zoeller JJ, Lin JR, Morganti S, Garrido-Castro AC, Tolaney SM, Li Z, Barbie DA, Sorger PK, Helin K, Santagata S, Knott SRV, Cichowski K. Schade AE, et al. Among authors: nguyen vtm. Nature. 2024 Nov;635(8039):755-763. doi: 10.1038/s41586-024-08031-6. Epub 2024 Oct 9. Nature. 2024. PMID: 39385030 Free PMC article.
Induction of the TEAD Coactivator VGLL1 by Estrogen Receptor-Targeted Therapy Drives Resistance in Breast Cancer.
Gemma C, Lai CF, Singh AK, Belfiore A, Portman N, Milioli HZ, Periyasamy M, Raafat S, Nicholls AJ, Davies CM, Patel NR, Simmons GM, Fan H, Nguyen VTM, Magnani L, Rakha E, Martin LA, Lim E, Coombes RC, Pruneri G, Buluwela L, Ali S. Gemma C, et al. Among authors: nguyen vtm. Cancer Res. 2024 Dec 16;84(24):4283-4297. doi: 10.1158/0008-5472.CAN-24-0013. Cancer Res. 2024. PMID: 39356622 Free PMC article.
Author Correction: TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression.
Ottaviani S, Stebbing J, Frampton AE, Zagorac S, Krell J, de Giorgio A, Trabulo SM, Nguyen VTM, Magnani L, Feng H, Giovannetti E, Funel N, Gress TM, Jiao LR, Lombardo Y, Lemoine NR, Heeschen C, Castellano L. Ottaviani S, et al. Among authors: nguyen vtm. Nat Commun. 2019 Aug 14;10(1):3738. doi: 10.1038/s41467-019-11752-2. Nat Commun. 2019. PMID: 31413295 Free PMC article.
Author Correction: Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion.
Nguyen VTM, Barozzi I, Faronato M, Lombardo Y, Steel JH, Patel N, Darbre P, Castellano L, Győrffy B, Woodley L, Rodriguez-Meira A, Patten DK, Vircillo V, Periyasamy M, Ali S, Frige G, Minucci S, Coombes RC, Magnani L. Nguyen VTM, et al. Nat Commun. 2019 Aug 6;10(1):3505. doi: 10.1038/s41467-019-11569-z. Nat Commun. 2019. PMID: 31388012 Free PMC article.
TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression.
Ottaviani S, Stebbing J, Frampton AE, Zagorac S, Krell J, de Giorgio A, Trabulo SM, Nguyen VTM, Magnani L, Feng H, Giovannetti E, Funel N, Gress TM, Jiao LR, Lombardo Y, Lemoine NR, Heeschen C, Castellano L. Ottaviani S, et al. Among authors: nguyen vtm. Nat Commun. 2018 May 10;9(1):1845. doi: 10.1038/s41467-018-03962-x. Nat Commun. 2018. PMID: 29748571 Free PMC article.
Genomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer.
Harrod A, Fulton J, Nguyen VTM, Periyasamy M, Ramos-Garcia L, Lai CF, Metodieva G, de Giorgio A, Williams RL, Santos DB, Gomez PJ, Lin ML, Metodiev MV, Stebbing J, Castellano L, Magnani L, Coombes RC, Buluwela L, Ali S. Harrod A, et al. Among authors: nguyen vtm. Oncogene. 2017 Apr 20;36(16):2286-2296. doi: 10.1038/onc.2016.382. Epub 2016 Oct 17. Oncogene. 2017. PMID: 27748765 Free PMC article.
Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion.
Nguyen VT, Barozzi I, Faronato M, Lombardo Y, Steel JH, Patel N, Darbre P, Castellano L, Győrffy B, Woodley L, Meira A, Patten DK, Vircillo V, Periyasamy M, Ali S, Frige G, Minucci S, Coombes RC, Magnani L. Nguyen VT, et al. Nat Commun. 2015 Nov 27;6:10044. doi: 10.1038/ncomms10044. Nat Commun. 2015. PMID: 26610607 Free PMC article.
APOBEC3B-Mediated Cytidine Deamination Is Required for Estrogen Receptor Action in Breast Cancer.
Periyasamy M, Patel H, Lai CF, Nguyen VTM, Nevedomskaya E, Harrod A, Russell R, Remenyi J, Ochocka AM, Thomas RS, Fuller-Pace F, Győrffy B, Caldas C, Navaratnam N, Carroll JS, Zwart W, Coombes RC, Magnani L, Buluwela L, Ali S. Periyasamy M, et al. Among authors: nguyen vtm. Cell Rep. 2015 Oct 6;13(1):108-121. doi: 10.1016/j.celrep.2015.08.066. Epub 2015 Sep 24. Cell Rep. 2015. PMID: 26411678 Free PMC article.
The pioneer factor PBX1 is a novel driver of metastatic progression in ERα-positive breast cancer.
Magnani L, Patten DK, Nguyen VT, Hong SP, Steel JH, Patel N, Lombardo Y, Faronato M, Gomes AR, Woodley L, Page K, Guttery D, Primrose L, Fernandez Garcia D, Shaw J, Viola P, Green A, Nolan C, Ellis IO, Rakha EA, Shousha S, Lam EW, Győrffy B, Lupien M, Coombes RC. Magnani L, et al. Oncotarget. 2015 Sep 8;6(26):21878-91. doi: 10.18632/oncotarget.4243. Oncotarget. 2015. PMID: 26215677 Free PMC article.
12 results