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Epigenetic and Oncogenic Inhibitors Cooperatively Drive Differentiation and Kill KRAS-Mutant Colorectal Cancers.
Loi P, Schade AE, Rodriguez CL, Krishnan A, Perurena N, Nguyen VTM, Xu Y, Watanabe M, Davis RA, Gardner A, Pilla NF, Mattioli K, Popow O, Gunduz N, Lannagan TRM, Fitzgerald S, Sicinska ET, Lin JR, Tan W, Brais LK, Haigis KM, Giannakis M, Ng K, Santagata S, Helin K, Sansom OJ, Cichowski K. Loi P, et al. Among authors: schade ae. Cancer Discov. 2024 Dec 2;14(12):2430-2449. doi: 10.1158/2159-8290.CD-23-0866. Cancer Discov. 2024. PMID: 39121480 Free PMC article.
AKT and EZH2 inhibitors kill TNBCs by hijacking mechanisms of involution.
Schade AE, Perurena N, Yang Y, Rodriguez CL, Krishnan A, Gardner A, Loi P, Xu Y, Nguyen VTM, Mastellone GM, Pilla NF, Watanabe M, Ota K, Davis RA, Mattioli K, Xiang D, Zoeller JJ, Lin JR, Morganti S, Garrido-Castro AC, Tolaney SM, Li Z, Barbie DA, Sorger PK, Helin K, Santagata S, Knott SRV, Cichowski K. Schade AE, et al. Nature. 2024 Nov;635(8039):755-763. doi: 10.1038/s41586-024-08031-6. Epub 2024 Oct 9. Nature. 2024. PMID: 39385030 Free PMC article.
MMB-FOXM1-driven premature mitosis is required for CHK1 inhibitor sensitivity.
Branigan TB, Kozono D, Schade AE, Deraska P, Rivas HG, Sambel L, Reavis HD, Shapiro GI, D'Andrea AD, DeCaprio JA. Branigan TB, et al. Among authors: schade ae. Cell Rep. 2021 Mar 2;34(9):108808. doi: 10.1016/j.celrep.2021.108808. Cell Rep. 2021. PMID: 33657372 Free PMC article.
Coordinating gene expression during the cell cycle.
Fischer M, Schade AE, Branigan TB, Müller GA, DeCaprio JA. Fischer M, et al. Among authors: schade ae. Trends Biochem Sci. 2022 Dec;47(12):1009-1022. doi: 10.1016/j.tibs.2022.06.007. Epub 2022 Jul 11. Trends Biochem Sci. 2022. PMID: 35835684 Free article. Review.
Crafting figures to describe cellular processes.
Kmiecik SW, Shi Q, Chen YG, Moormann J, Hildebrandt TM, Schade A, Fischer M, Kim KQ. Kmiecik SW, et al. Trends Biochem Sci. 2023 Jun;48(6):491-494. doi: 10.1016/j.tibs.2022.09.004. Trends Biochem Sci. 2023. PMID: 37172571 No abstract available.
48 results