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LAG-3 sustains TOX expression and regulates the CD94/NKG2-Qa-1b axis to govern exhausted CD8 T cell NK receptor expression and cytotoxicity.
Ngiow SF, Manne S, Huang YJ, Azar T, Chen Z, Mathew D, Chen Q, Khan O, Wu JE, Alcalde V, Flowers AJ, McClain S, Baxter AE, Kurachi M, Shi J, Huang AC, Giles JR, Sharpe AH, Vignali DAA, Wherry EJ. Ngiow SF, et al. Among authors: khan o. Cell. 2024 Aug 8;187(16):4336-4354.e19. doi: 10.1016/j.cell.2024.07.018. Cell. 2024. PMID: 39121847
In Vitro Modeling of CD8 T Cell Exhaustion Enables CRISPR Screening to Reveal a Role for BHLHE40.
Wu JE, Manne S, Ngiow SF, Baxter AE, Huang H, Freilich E, Clark ML, Lee JH, Chen Z, Khan O, Staupe RP, Huang YJ, Shi J, Giles JR, Wherry EJ. Wu JE, et al. Among authors: khan o. bioRxiv [Preprint]. 2023 Apr 17:2023.04.17.537229. doi: 10.1101/2023.04.17.537229. bioRxiv. 2023. Update in: Sci Immunol. 2023 Aug 25;8(86):eade3369. doi: 10.1126/sciimmunol.ade3369 PMID: 37131713 Free PMC article. Updated. Preprint.
Clinical and demographic factors modify the association between plasma phosphorylated tau-181 and cognition.
Bolton CJ, Steinbach M, Khan OA, Liu D, O'Malley J, Dumitrescu L, Peterson A, Jefferson AL, Hohman TJ, Zetterberg H, Gifford KA; Alzheimer's Disease Neuroimaging Initiative. Bolton CJ, et al. Among authors: khan oa. Alzheimers Dement (Amst). 2024 Dec 20;16(4):e70047. doi: 10.1002/dad2.70047. eCollection 2024 Oct-Dec. Alzheimers Dement (Amst). 2024. PMID: 39713247 Free PMC article.
938 results