Chen GZ - Search Results

1

Cyy-272, an indazole derivative, effectively mitigates obese cardiomyopathy as a JNK inhibitor.

Liu X, Cheng LT, Ye QR, Gao HC, Zhu JW, Zhao K, Liu HM, Wang YJ, Alinejad T, Zhang XH, Chen GZ. Liu X, et al. Among authors: chen gz. Biomed Pharmacother. 2024 Sep;178:117172. doi: 10.1016/j.biopha.2024.117172. Epub 2024 Aug 11. Biomed Pharmacother. 2024. PMID: 39128188 Free article.

2

Synthesis and biological evaluation of novel thiazolidinone derivatives as potential anti-inflammatory agents.

Hu J, Wang Y, Wei X, Wu X, Chen G, Cao G, Shen X, Zhang X, Tang Q, Liang G, Li X. Hu J, et al. Eur J Med Chem. 2013 Jun;64:292-301. doi: 10.1016/j.ejmech.2013.04.010. Epub 2013 Apr 10. Eur J Med Chem. 2013. PMID: 23644212

3

Compound LM9, a novel MyD88 inhibitor, efficiently mitigates inflammatory responses and fibrosis in obesity-induced cardiomyopathy.

Zheng XY, Sun CC, Liu Q, Lu XY, Fu LL, Liang G, Zhang XH, Chen GZ. Zheng XY, et al. Among authors: chen gz. Acta Pharmacol Sin. 2020 Aug;41(8):1093-1101. doi: 10.1038/s41401-020-0410-x. Epub 2020 Apr 27. Acta Pharmacol Sin. 2020. PMID: 32341464 Free PMC article.

4

Bicyclol ameliorates nonalcoholic fatty liver disease in mice via inhibiting MAPKs and NF-κB signaling pathways.

Zhao W, Yan Y, Xiao Z, Wang M, Xu M, Wang Z, Wang Y, Zhuang Z, Yang D, Chen G, Liang G. Zhao W, et al. Biomed Pharmacother. 2021 Sep;141:111874. doi: 10.1016/j.biopha.2021.111874. Epub 2021 Jul 3. Biomed Pharmacother. 2021. PMID: 34229251 Free article.

5

A novel indazole derivative, compound Cyy-272, attenuates LPS-induced acute lung injury by inhibiting JNK phosphorylation.

Liu Q, Yan H, Zheng X, Fu L, Bao Y, Zheng H, Liu Z, Zhang X, Chen G. Liu Q, et al. Toxicol Appl Pharmacol. 2021 Oct 1;428:115648. doi: 10.1016/j.taap.2021.115648. Epub 2021 Jul 17. Toxicol Appl Pharmacol. 2021. PMID: 34280409

6

Structural basis for FGF hormone signalling.

Chen L, Fu L, Sun J, Huang Z, Fang M, Zinkle A, Liu X, Lu J, Pan Z, Wang Y, Liang G, Li X, Chen G, Mohammadi M. Chen L, et al. Nature. 2023 Jun;618(7966):862-870. doi: 10.1038/s41586-023-06155-9. Epub 2023 Jun 7. Nature. 2023. PMID: 37286607 Free PMC article.

7

Hypericin Alleviates Chronic Kidney Disease-induced Left Ventricular Hypertrophy by Regulation of FGF23-FGFR4 Signaling Pathway.

Liu M, Cheng L, Ye Q, Liu H, Shu C, Gao H, Liu X, Zhang X, Chen G. Liu M, et al. J Cardiovasc Pharmacol. 2024 Jun 1;83(6):588-601. doi: 10.1097/FJC.0000000000001559. J Cardiovasc Pharmacol. 2024. PMID: 38547517

8

New drug combination regimen based on pharmacokinetic characteristics-Erdafitinib combined with sertraline or duloxetine.

Zhang XD, Xu XY, Zhong YS, Zhang ZY, Jin LH, Luo JC, Ye F, Ni JH, Chen J, Chen GZ, Qian JC, Liu ZG. Zhang XD, et al. Among authors: chen gz. Biomed Pharmacother. 2024 Oct;179:117414. doi: 10.1016/j.biopha.2024.117414. Epub 2024 Sep 10. Biomed Pharmacother. 2024. PMID: 39260324 Free article.

9

Compound SJ-12 attenuates streptozocin-induced diabetic cardiomyopathy by stabilizing SERCA2a.

Lou S, Zhu W, Yu T, Zhang Q, Wang M, Jin L, Xiong Y, Xu J, Wang Q, Chen G, Liang G, Hu X, Luo W. Lou S, et al. Biochim Biophys Acta Mol Basis Dis. 2024 Jun;1870(5):167140. doi: 10.1016/j.bbadis.2024.167140. Epub 2024 Mar 26. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 38548092

10

Discovery of a New Inhibitor of Myeloid Differentiation 2 from Cinnamamide Derivatives with Anti-Inflammatory Activity in Sepsis and Acute Lung Injury.

Chen G, Zhang Y, Liu X, Fang Q, Wang Z, Fu L, Liu Z, Wang Y, Zhao Y, Li X, Liang G. Chen G, et al. J Med Chem. 2016 Mar 24;59(6):2436-51. doi: 10.1021/acs.jmedchem.5b01574. Epub 2016 Mar 11. J Med Chem. 2016. PMID: 26937738

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