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Page 1
Neutralization activity in chronic HIV infection is characterized by a distinct programming of follicular helper CD4 T cells.
Moysi E, Sharma AA, O'Dell S, Georgakis S, Del Rio Estrada PM, Torres-Ruiz F, Navarro MG, Villalobos YAL, Rios SA, Reyes-Teran G, Beddall MH, Ko SH, Belinky F, Orfanakis M, de Leval L, Enriquez AB, Buckner CM, Moir S, Doria-Rose N, Boritz E, Mascola JR, Sekaly RP, Koup RA, Petrovas C. Moysi E, et al. Among authors: sekaly rp. bioRxiv [Preprint]. 2024 Aug 3:2024.07.31.605954. doi: 10.1101/2024.07.31.605954. bioRxiv. 2024. PMID: 39131331 Free PMC article. Preprint.
Single cell analysis reveals an antiviral network that controls Zika virus infection in human dendritic cells.
Moore KM, Pelletier AN, Lapp S, Metz A, Tharp GK, Lee M, Bhasin SS, Bhasin M, Sékaly RP, Bosinger SE, Suthar MS. Moore KM, et al. Among authors: sekaly rp. bioRxiv [Preprint]. 2024 Jan 21:2024.01.19.576293. doi: 10.1101/2024.01.19.576293. bioRxiv. 2024. Update in: J Virol. 2024 May 14;98(5):e0019424. doi: 10.1128/jvi.00194-24. PMID: 38293140 Free PMC article. Updated. Preprint.
TREM2+ and interstitial macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaques.
Upadhyay AA, Hoang TN, Pino M, Boddapati AK, Viox EG, Lee MYH, Corry J, Strongin Z, Cowan DA, Beagle EN, Horton TR, Hamilton S, Aoued H, Harper JL, Nguyen K, Pellegrini KL, Tharp GK, Piantadosi A, Levit RD, Amara RR, Barratt-Boyes SM, Ribeiro SP, Sekaly RP, Vanderford TH, Schinazi RF, Paiardini M, Bosinger SE. Upadhyay AA, et al. Among authors: sekaly rp. bioRxiv [Preprint]. 2021 Oct 5:2021.10.05.463212. doi: 10.1101/2021.10.05.463212. bioRxiv. 2021. Update in: Nat Commun. 2023 Apr 6;14(1):1914. doi: 10.1038/s41467-023-37425-9. PMID: 34642693 Free PMC article. Updated. Preprint.
Schistosoma mansoni infection alters the host pre-vaccination environment resulting in blunted Hepatitis B vaccination immune responses.
Muir R, Metcalf T, Fourati S, Bartsch Y, Lugemwa JK, Canderan G, Alter G, Muyanja E, Okech B, Namatovu T, Namara I, Namuniina A, Ssetaala A, Mpendo J, Nanvubya A, Kitandwe PK, Bagaya BS, Kiwanuka N, Nassuna J, Biribawa VM, Elliott AM, de Dood CJ, Senyonga W, Balungi P, Kaleebu P, Mayanja Y, Odongo M, Fast P, Price MA, Corstjens PLAM, van Dam GJ, Kamali A, Sekaly RP, Haddad EK. Muir R, et al. Among authors: sekaly rp. medRxiv [Preprint]. 2023 Feb 26:2023.02.24.23284435. doi: 10.1101/2023.02.24.23284435. medRxiv. 2023. Update in: PLoS Negl Trop Dis. 2023 Jul 5;17(7):e0011089. doi: 10.1371/journal.pntd.0011089. PMID: 36865336 Free PMC article. Updated. Preprint.
Human immune organoids to decode B cell response in healthy donors and patients with lymphoma.
Zhong Z, Quiñones-Pérez M, Dai Z, Juarez VM, Bhatia E, Carlson CR, Shah SB, Patel A, Fang Z, Hu T, Allam M, Hicks SL, Gupta M, Gupta SL, Weeks E, Vagelos SD, Molina A, Mulero-Russe A, Mora-Boza A, Joshi DJ, Sekaly RP, Sulchek T, Goudy SL, Wrammert J, Roy K, Boss JM, Coskun AF, Scharer CD, García AJ, Koff JL, Singh A. Zhong Z, et al. Among authors: sekaly rp. Nat Mater. 2024 Nov 6. doi: 10.1038/s41563-024-02037-1. Online ahead of print. Nat Mater. 2024. PMID: 39506098
Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption.
Pereira Ribeiro S, Strongin Z, Soudeyns H, Ten-Caten F, Ghneim K, Pacheco Sanchez G, Xavier de Medeiros G, Del Rio Estrada PM, Pelletier AN, Hoang T, Nguyen K, Harper J, Jean S, Wallace C, Balderas R, Lifson JD, Raghunathan G, Rimmer E, Pastuskova C, Wu G, Micci L, Ribeiro RM, Chan CN, Estes JD, Silvestri G, Gorman DM, Howell BJ, Hazuda DJ, Paiardini M, Sekaly RP. Pereira Ribeiro S, et al. Among authors: sekaly rp. Nat Immunol. 2024 Oct;25(10):1900-1912. doi: 10.1038/s41590-024-01952-4. Epub 2024 Sep 12. Nat Immunol. 2024. PMID: 39266691 Free PMC article.
Administration of anti-HIV-1 broadly neutralizing monoclonal antibodies with increased affinity to Fcγ receptors during acute SHIVAD8-EO infection.
Dias J, Fabozzi G, Fourati S, Chen X, Liu C, Ambrozak DR, Ransier A, Laboune F, Hu J, Shi W, March K, Maximova AA, Schmidt SD, Samsel J, Talana CA, Ernste K, Ko SH, Lucas ME, Radecki PE, Boswell KL, Nishimura Y, Todd JP, Martin MA, Petrovas C, Boritz EA, Doria-Rose NA, Douek DC, Sékaly RP, Lifson JD, Asokan M, Gama L, Mascola JR, Pegu A, Koup RA. Dias J, et al. Among authors: sekaly rp. Nat Commun. 2024 Aug 29;15(1):7461. doi: 10.1038/s41467-024-51848-y. Nat Commun. 2024. PMID: 39198422 Free PMC article.
Intestinal helminth infection impairs vaccine-induced T cell responses and protection against SARS-CoV-2 in mice.
Desai P, Karl CE, Ying B, Liang CY, Garcia-Salum T, Santana AC, Ten-Caten F, Joseph F Urban Jr, Elbashir SM, Edwards DK, Ribeiro SP, Thackray LB, Sekaly RP, Diamond MS. Desai P, et al. Among authors: sekaly rp. Sci Transl Med. 2024 Aug 21;16(761):eado1941. doi: 10.1126/scitranslmed.ado1941. Epub 2024 Aug 21. Sci Transl Med. 2024. PMID: 39167662
A pre-vaccination immune metabolic interplay determines the protective antibody response to a dengue virus vaccine.
Pelletier AN, Sanchez GP, Izmirly A, Watson M, Di Pucchio T, Carvalho KI, Filali-Mouhim A, Paramithiotis E, Timenetsky MDCST, Precioso AR, Kalil J, Diamond MS, Haddad EK, Kallas EG, Sekaly RP. Pelletier AN, et al. Among authors: sekaly rp. Cell Rep. 2024 Jul 23;43(7):114370. doi: 10.1016/j.celrep.2024.114370. Epub 2024 Jun 18. Cell Rep. 2024. PMID: 38900640 Free PMC article.
Integrated longitudinal multiomics study identifies immune programs associated with acute COVID-19 severity and mortality.
Gygi JP, Maguire C, Patel RK, Shinde P, Konstorum A, Shannon CP, Xu L, Hoch A, Jayavelu ND, Haddad EK; IMPACC Network; Reed EF, Kraft M, McComsey GA, Metcalf JP, Ozonoff A, Esserman D, Cairns CB, Rouphael N, Bosinger SE, Kim-Schulze S, Krammer F, Rosen LB, van Bakel H, Wilson M, Eckalbar WL, Maecker HT, Langelier CR, Steen H, Altman MC, Montgomery RR, Levy O, Melamed E, Pulendran B, Diray-Arce J, Smolen KK, Fragiadakis GK, Becker PM, Sekaly RP, Ehrlich LI, Fourati S, Peters B, Kleinstein SH, Guan L. Gygi JP, et al. Among authors: sekaly rp. J Clin Invest. 2024 May 1;134(9):e176640. doi: 10.1172/JCI176640. J Clin Invest. 2024. PMID: 38690733 Free PMC article.
389 results