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Preclinical spheroid models identify BMX as a therapeutic target for metastatic MYCN nonamplified neuroblastoma.
Sundaramoorthy S, Colombo DF, Sanalkumar R, Broye L, Balmas Bourloud K, Boulay G, Cironi L, Stamenkovic I, Renella R, Kuttler F, Turcatti G, Rivera MN, Mühlethaler-Mottet A, Bardet AF, Riggi N. Sundaramoorthy S, et al. Among authors: cironi l. JCI Insight. 2024 Jul 22;9(14):e169647. doi: 10.1172/jci.insight.169647. JCI Insight. 2024. PMID: 39133652 Free PMC article.
EZH2 is essential for glioblastoma cancer stem cell maintenance.
Suvà ML, Riggi N, Janiszewska M, Radovanovic I, Provero P, Stehle JC, Baumer K, Le Bitoux MA, Marino D, Cironi L, Marquez VE, Clément V, Stamenkovic I. Suvà ML, et al. Among authors: cironi l. Cancer Res. 2009 Dec 15;69(24):9211-8. doi: 10.1158/0008-5472.CAN-09-1622. Cancer Res. 2009. PMID: 19934320
EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cells.
Riggi N, Suvà ML, De Vito C, Provero P, Stehle JC, Baumer K, Cironi L, Janiszewska M, Petricevic T, Suvà D, Tercier S, Joseph JM, Guillou L, Stamenkovic I. Riggi N, et al. Among authors: cironi l. Genes Dev. 2010 May;24(9):916-32. doi: 10.1101/gad.1899710. Epub 2010 Apr 9. Genes Dev. 2010. PMID: 20382729 Free PMC article.
The chromatin landscape of primary synovial sarcoma organoids is linked to specific epigenetic mechanisms and dependencies.
Boulay G, Cironi L, Garcia SP, Rengarajan S, Xing YH, Lee L, Awad ME, Naigles B, Iyer S, Broye LC, Keskin T, Cauderay A, Fusco C, Letovanec I, Chebib I, Nielsen PG, Tercier S, Cherix S, Nguyen-Ngoc T, Cote G, Choy E, Provero P, Suvà ML, Rivera MN, Stamenkovic I, Riggi N. Boulay G, et al. Among authors: cironi l. Life Sci Alliance. 2020 Dec 23;4(2):e202000808. doi: 10.26508/lsa.202000808. Print 2021 Feb. Life Sci Alliance. 2020. PMID: 33361335 Free PMC article.
CIC-DUX4 Chromatin Profiling Reveals New Epigenetic Dependencies and Actionable Therapeutic Targets in CIC-Rearranged Sarcomas.
Bakaric A, Cironi L, Praz V, Sanalkumar R, Broye LC, Favre-Bulle K, Letovanec I, Digklia A, Renella R, Stamenkovic I, Ott CJ, Nakamura T, Antonescu CR, Rivera MN, Riggi N. Bakaric A, et al. Among authors: cironi l. Cancers (Basel). 2024 Jan 21;16(2):457. doi: 10.3390/cancers16020457. Cancers (Basel). 2024. PMID: 38275898 Free PMC article.
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