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Variant-proof high affinity ACE2 antagonist limits SARS-CoV-2 replication in upper and lower airways.
Gagne M, Flynn BJ, Honeycutt CC, Flebbe DR, Andrew SF, Provost SJ, McCormick L, Van Ry A, McCarthy E, Todd JM, Bao S, Teng IT, Marciano S, Rudich Y, Li C, Jain S, Wali B, Pessaint L, Dodson A, Cook A, Lewis MG, Andersen H, Zahradník J, Suthar MS, Nason MC, Foulds KE, Kwong PD, Roederer M, Schreiber G, Seder RA, Douek DC. Gagne M, et al. Among authors: zahradnik j. Nat Commun. 2024 Aug 12;15(1):6894. doi: 10.1038/s41467-024-51046-w. Nat Commun. 2024. PMID: 39134521 Free PMC article.
Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants.
Tamura T, Ito J, Uriu K, Zahradnik J, Kida I, Anraku Y, Nasser H, Shofa M, Oda Y, Lytras S, Nao N, Itakura Y, Deguchi S, Suzuki R, Wang L, Begum MM, Kita S, Yajima H, Sasaki J, Sasaki-Tabata K, Shimizu R, Tsuda M, Kosugi Y, Fujita S, Pan L, Sauter D, Yoshimatsu K, Suzuki S, Asakura H, Nagashima M, Sadamasu K, Yoshimura K, Yamamoto Y, Nagamoto T, Schreiber G, Maenaka K; Genotype to Phenotype Japan (G2P-Japan) Consortium; Hashiguchi T, Ikeda T, Fukuhara T, Saito A, Tanaka S, Matsuno K, Takayama K, Sato K. Tamura T, et al. Among authors: zahradnik j. Nat Commun. 2023 May 16;14(1):2800. doi: 10.1038/s41467-023-38435-3. Nat Commun. 2023. PMID: 37193706 Free PMC article.
SARS-CoV-2 spike L452R variant evades cellular immunity and increases infectivity.
Motozono C, Toyoda M, Zahradnik J, Saito A, Nasser H, Tan TS, Ngare I, Kimura I, Uriu K, Kosugi Y, Yue Y, Shimizu R, Ito J, Torii S, Yonekawa A, Shimono N, Nagasaki Y, Minami R, Toya T, Sekiya N, Fukuhara T, Matsuura Y, Schreiber G; Genotype to Phenotype Japan (G2P-Japan) Consortium; Ikeda T, Nakagawa S, Ueno T, Sato K. Motozono C, et al. Among authors: zahradnik j. Cell Host Microbe. 2021 Jul 14;29(7):1124-1136.e11. doi: 10.1016/j.chom.2021.06.006. Epub 2021 Jun 15. Cell Host Microbe. 2021. PMID: 34171266 Free PMC article.
Convergent evolution of SARS-CoV-2 Omicron subvariants leading to the emergence of BQ.1.1 variant.
Ito J, Suzuki R, Uriu K, Itakura Y, Zahradnik J, Kimura KT, Deguchi S, Wang L, Lytras S, Tamura T, Kida I, Nasser H, Shofa M, Begum MM, Tsuda M, Oda Y, Suzuki T, Sasaki J, Sasaki-Tabata K, Fujita S, Yoshimatsu K, Ito H, Nao N, Asakura H, Nagashima M, Sadamasu K, Yoshimura K, Yamamoto Y, Nagamoto T, Kuramochi J, Schreiber G; Genotype to Phenotype Japan (G2P-Japan) Consortium; Saito A, Matsuno K, Takayama K, Hashiguchi T, Tanaka S, Fukuhara T, Ikeda T, Sato K. Ito J, et al. Among authors: zahradnik j. Nat Commun. 2023 May 11;14(1):2671. doi: 10.1038/s41467-023-38188-z. Nat Commun. 2023. PMID: 37169744 Free PMC article.
The SARS-CoV-2 Lambda variant exhibits enhanced infectivity and immune resistance.
Kimura I, Kosugi Y, Wu J, Zahradnik J, Yamasoba D, Butlertanaka EP, Tanaka YL, Uriu K, Liu Y, Morizako N, Shirakawa K, Kazuma Y, Nomura R, Horisawa Y, Tokunaga K, Ueno T, Takaori-Kondo A, Schreiber G, Arase H; Genotype to Phenotype Japan (G2P-Japan) Consortium; Motozono C, Saito A, Nakagawa S, Sato K. Kimura I, et al. Among authors: zahradnik j. Cell Rep. 2022 Jan 11;38(2):110218. doi: 10.1016/j.celrep.2021.110218. Epub 2021 Dec 18. Cell Rep. 2022. PMID: 34968415 Free PMC article.
104 results