Liefke R - Search Results

1

SAMD1 suppresses epithelial-mesenchymal transition pathways in pancreatic ductal adenocarcinoma.

Simon C, Brunke ID, Stielow B, Forné I, Steitz AM, Geller M, Rohner I, Weber LM, Fischer S, Jeude LM, Huber T, Nist A, Stiewe T, Huber M, Buchholz M, Liefke R. Simon C, et al. Among authors: liefke r. PLoS Biol. 2024 Aug 13;22(8):e3002739. doi: 10.1371/journal.pbio.3002739. eCollection 2024 Aug. PLoS Biol. 2024. PMID: 39137238 Free PMC article.

2

The CpG Island-Binding Protein SAMD1 Contributes to an Unfavorable Gene Signature in HepG2 Hepatocellular Carcinoma Cells.

Simon C, Stielow B, Nist A, Rohner I, Weber LM, Geller M, Fischer S, Stiewe T, Liefke R. Simon C, et al. Among authors: liefke r. Biology (Basel). 2022 Apr 6;11(4):557. doi: 10.3390/biology11040557. Biology (Basel). 2022. PMID: 35453756 Free PMC article.

3

IRF8 Is an AML-Specific Susceptibility Factor That Regulates Signaling Pathways and Proliferation of AML Cells.

Liss F, Frech M, Wang Y, Giel G, Fischer S, Simon C, Weber LM, Nist A, Stiewe T, Neubauer A, Burchert A, Liefke R. Liss F, et al. Among authors: liefke r. Cancers (Basel). 2021 Feb 12;13(4):764. doi: 10.3390/cancers13040764. Cancers (Basel). 2021. PMID: 33673123 Free PMC article.

4

The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands.

Stielow B, Zhou Y, Cao Y, Simon C, Pogoda HM, Jiang J, Ren Y, Phanor SK, Rohner I, Nist A, Stiewe T, Hammerschmidt M, Shi Y, Bulyk ML, Wang Z, Liefke R. Stielow B, et al. Among authors: liefke r. Sci Adv. 2021 May 12;7(20):eabf2229. doi: 10.1126/sciadv.abf2229. Print 2021 May. Sci Adv. 2021. PMID: 33980486 Free PMC article.

5

Making fundamental scientific discoveries by combining information from literature, databases, and computational tools - An example.

Stielow B, Simon C, Liefke R. Stielow B, et al. Among authors: liefke r. Comput Struct Biotechnol J. 2021 May 14;19:3027-3033. doi: 10.1016/j.csbj.2021.04.052. eCollection 2021. Comput Struct Biotechnol J. 2021. PMID: 34136100 Free PMC article. Review.

6

The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain.

Weber LM, Jia Y, Stielow B, Gisselbrecht SS, Cao Y, Ren Y, Rohner I, King J, Rothman E, Fischer S, Simon C, Forné I, Nist A, Stiewe T, Bulyk ML, Wang Z, Liefke R. Weber LM, et al. Among authors: liefke r. Nucleic Acids Res. 2023 Jan 25;51(2):574-594. doi: 10.1093/nar/gkac1188. Nucleic Acids Res. 2023. PMID: 36537216 Free PMC article.

7

IRF2BP2 counteracts the ATF7/JDP2 AP-1 heterodimer to prevent inflammatory overactivation in acute myeloid leukemia (AML) cells.

Fischer S, Weber LM, Stielow B, Frech M, Simon C, Geller M, Könnecke J, Finkernagel F, Forné I, Nist A, Bauer UM, Stiewe T, Neubauer A, Liefke R. Fischer S, et al. Among authors: liefke r. Nucleic Acids Res. 2024 Jul 22;52(13):7590-7609. doi: 10.1093/nar/gkae437. Nucleic Acids Res. 2024. PMID: 38801077 Free PMC article.

8

Evolutionary adaptation of the Polycomb repressive complex 2.

Fischer S, Weber LM, Liefke R. Fischer S, et al. Among authors: liefke r. Epigenetics Chromatin. 2022 Feb 22;15(1):7. doi: 10.1186/s13072-022-00439-6. Epigenetics Chromatin. 2022. PMID: 35193659 Free PMC article. Review.

9

Investigation of SAMD1 ablation in mice.

Campbell B, Weber LM, Engle SJ, Ozolinš TRS, Bourassa P, Aiello R, Liefke R. Campbell B, et al. Among authors: liefke r. Sci Rep. 2023 Feb 21;13(1):3000. doi: 10.1038/s41598-023-29779-3. Sci Rep. 2023. PMID: 36810619 Free PMC article.

10

Polycomb-like Proteins in Gene Regulation and Cancer.

Fischer S, Liefke R. Fischer S, et al. Among authors: liefke r. Genes (Basel). 2023 Apr 18;14(4):938. doi: 10.3390/genes14040938. Genes (Basel). 2023. PMID: 37107696 Free PMC article. Review.

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