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Mispacking of the F87 sidechain drives aggregation-promoting conformational fluctuations in the subunit interfaces of the transthyretin tetramer.
Sun X, Ferguson JA, Yang K, Stanfield RL, Dyson HJ, Wright PE. Sun X, et al. Among authors: ferguson ja. bioRxiv [Preprint]. 2024 Mar 1:2024.02.26.582172. doi: 10.1101/2024.02.26.582172. bioRxiv. 2024. Update in: Protein Sci. 2024 Sep;33(9):e5101. doi: 10.1002/pro.5101 PMID: 38464206 Free PMC article. Updated. Preprint.
Assessing AF2's ability to predict structural ensembles of proteins.
Riccabona JR, Spoendlin FC, Fischer AM, Loeffler JR, Quoika PK, Jenkins TP, Ferguson JA, Smorodina E, Laustsen AH, Greiff V, Forli S, Ward AB, Deane CM, Fernández-Quintero ML. Riccabona JR, et al. Among authors: ferguson ja. Structure. 2024 Nov 7;32(11):2147-2159.e2. doi: 10.1016/j.str.2024.09.001. Epub 2024 Sep 26. Structure. 2024. PMID: 39332396
Flipping hemagglutinin on its head.
Ferguson JA, Han J, Ward AB. Ferguson JA, et al. Nat Chem Biol. 2024 Aug;20(8):944-945. doi: 10.1038/s41589-024-01545-0. Nat Chem Biol. 2024. PMID: 38321208 No abstract available.
Broadly inhibitory antibodies to severe malaria virulence proteins.
Reyes RA, Raghavan SSR, Hurlburt NK, Introini V, Bol S, Kana IH, Jensen RW, Martinez-Scholze E, Gestal-Mato M, López-Gutiérrez B, Sanz S, Bancells C, Fernández-Quintero ML, Loeffler JR, Ferguson JA, Lee WH, Martin GM, Theander TG, Lusingu JPA, Minja DTR, Ssewanyana I, Feeney ME, Greenhouse B, Ward AB, Bernabeu M, Pancera M, Turner L, Bunnik EM, Lavstsen T. Reyes RA, et al. Among authors: ferguson ja. Nature. 2024 Dec;636(8041):182-189. doi: 10.1038/s41586-024-08220-3. Epub 2024 Nov 20. Nature. 2024. PMID: 39567685
Defining bottlenecks and opportunities for Lassa virus neutralization by structural profiling of vaccine-induced polyclonal antibody responses.
Brouwer PJM, Perrett HR, Beaumont T, Nijhuis H, Kruijer S, Burger JA, Bontjer I, Lee WH, Ferguson JA, Schauflinger M, Müller-Kräuter H, Sanders RW, Strecker T, van Gils MJ, Ward AB. Brouwer PJM, et al. Among authors: ferguson ja. Cell Rep. 2024 Sep 24;43(9):114708. doi: 10.1016/j.celrep.2024.114708. Epub 2024 Sep 6. Cell Rep. 2024. PMID: 39243373 Free PMC article.
166 results