Doveston RG - Search Results

1

Dissecting the functional behavior of the differentially phosphorylated prolyl isomerase, Pin1.

Kay DF, Ozleyen A, Heras CML, Doveston RG, Leney AC. Kay DF, et al. Among authors: doveston rg. Protein Sci. 2024 Sep;33(9):e5138. doi: 10.1002/pro.5138. Protein Sci. 2024. PMID: 39150071 Free PMC article.

2

Harnessing the 14-3-3 protein-protein interaction network.

Pitasse-Santos P, Hewitt-Richards I, Abeywickrama Wijewardana Sooriyaarachchi MD, Doveston RG. Pitasse-Santos P, et al. Among authors: doveston rg. Curr Opin Struct Biol. 2024 Jun;86:102822. doi: 10.1016/j.sbi.2024.102822. Epub 2024 Apr 28. Curr Opin Struct Biol. 2024. PMID: 38685162 Free article. Review.

3

Characterizing the protein-protein interaction between MDM2 and 14-3-3σ; proof of concept for small molecule stabilization.

Ward JA, Romartinez-Alonso B, Kay DF, Bellamy-Carter J, Thurairajah B, Basran J, Kwon H, Leney AC, Macip S, Roversi P, Muskett FW, Doveston RG. Ward JA, et al. Among authors: doveston rg. J Biol Chem. 2024 Feb;300(2):105651. doi: 10.1016/j.jbc.2024.105651. Epub 2024 Jan 16. J Biol Chem. 2024. PMID: 38237679 Free PMC article.

4

Tracking the mechanism of covalent molecular glue stabilization using native mass spectrometry.

Verhoef CJA, Kay DF, van Dijck L, Doveston RG, Brunsveld L, Leney AC, Cossar PJ. Verhoef CJA, et al. Among authors: doveston rg. Chem Sci. 2023 May 31;14(24):6756-6762. doi: 10.1039/d3sc01732j. eCollection 2023 Jun 21. Chem Sci. 2023. PMID: 37350830 Free PMC article.

5

Contemporary biophysical approaches for studying 14-3-3 protein-protein interactions.

Thurairajah B, Hudson AJ, Doveston RG. Thurairajah B, et al. Among authors: doveston rg. Front Mol Biosci. 2022 Nov 8;9:1043673. doi: 10.3389/fmolb.2022.1043673. eCollection 2022. Front Mol Biosci. 2022. PMID: 36425654 Free PMC article. Review.

6

Cooperative stabilisation of 14-3-3σ protein-protein interactions via covalent protein modification.

Falcicchio M, Ward JA, Chothia SY, Basran J, Mohindra A, Macip S, Roversi P, Doveston RG. Falcicchio M, et al. Among authors: doveston rg. Chem Sci. 2021 Sep 6;12(39):12985-12992. doi: 10.1039/d1sc02120f. eCollection 2021 Oct 13. Chem Sci. 2021. PMID: 34745529 Free PMC article.

7

Discovering protein-protein interaction stabilisers by native mass spectrometry.

Bellamy-Carter J, Mohata M, Falcicchio M, Basran J, Higuchi Y, Doveston RG, Leney AC. Bellamy-Carter J, et al. Among authors: doveston rg. Chem Sci. 2021 Jul 7;12(32):10724-10731. doi: 10.1039/d1sc01450a. eCollection 2021 Aug 18. Chem Sci. 2021. PMID: 34447561 Free PMC article.

8

Structure-Activity Relationship Studies of Trisubstituted Isoxazoles as Selective Allosteric Ligands for the Retinoic-Acid-Receptor-Related Orphan Receptor γt.

Meijer FA, Saris AOWM, Doveston RG, Oerlemans GJM, de Vries RMJM, Somsen BA, Unger A, Klebl B, Ottmann C, Cossar PJ, Brunsveld L. Meijer FA, et al. Among authors: doveston rg. J Med Chem. 2021 Jul 8;64(13):9238-9258. doi: 10.1021/acs.jmedchem.1c00475. Epub 2021 May 19. J Med Chem. 2021. PMID: 34008974 Free PMC article.

9

Covalent Occlusion of the RORγt Ligand Binding Pocket Allows Unambiguous Targeting of an Allosteric Site.

Meijer FA, van den Oetelaar MCM, Doveston RG, Sampers ENR, Brunsveld L. Meijer FA, et al. Among authors: doveston rg. ACS Med Chem Lett. 2021 Mar 8;12(4):631-639. doi: 10.1021/acsmedchemlett.1c00029. eCollection 2021 Apr 8. ACS Med Chem Lett. 2021. PMID: 33854703 Free PMC article.

10

Cooperativity between the orthosteric and allosteric ligand binding sites of RORγt.

de Vries RMJM, Meijer FA, Doveston RG, Leijten-van de Gevel IA, Brunsveld L. de Vries RMJM, et al. Among authors: doveston rg. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2021287118. doi: 10.1073/pnas.2021287118. Proc Natl Acad Sci U S A. 2021. PMID: 33536342 Free PMC article.

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