Musso DL - Search Results

1

Identification of small molecule antagonists of sonic hedgehog/heparin binding with activity in hedgehog functional assays.

Lamson DR, Tarpley M, Addo K, Ji X, Abu Rabe D, Ehe B, Hughes M, Smith GR, Daye LR, Musso DL, Zheng W, Williams KP. Lamson DR, et al. Among authors: musso dl. Biochim Biophys Acta Gen Subj. 2024 Nov;1868(11):130692. doi: 10.1016/j.bbagen.2024.130692. Epub 2024 Aug 14. Biochim Biophys Acta Gen Subj. 2024. PMID: 39151833

2

N-substituted phenylbenzamides of the niclosamide chemotype attenuate obesity related changes in high fat diet fed mice.

Bhagat HA, Compton SA, Musso DL, Laudeman CP, Jackson KMP, Yi NY, Nierobisz LS, Forsberg L, Brenman JE, Sexton JZ. Bhagat HA, et al. Among authors: musso dl. PLoS One. 2018 Oct 25;13(10):e0204605. doi: 10.1371/journal.pone.0204605. eCollection 2018. PLoS One. 2018. PMID: 30359371 Free PMC article.

3

Discovery of small molecule agonists for the bombesin receptor subtype 3 (BRS-3) based on an omeprazole lead.

Carlton DL, Collin-Smith LJ, Daniels AJ, Deaton DN, Goetz AS, Laudeman CP, Littleton TR, Musso DL, Morgan RJ, Szewczyk JR, Zhang C. Carlton DL, et al. Among authors: musso dl. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5451-5. doi: 10.1016/j.bmcl.2008.09.033. Epub 2008 Sep 11. Bioorg Med Chem Lett. 2008. PMID: 18818070

4

Synthesis of novel anilinoquinolines as c-fms inhibitors.

Smalley TL Jr, Chamberlain SD, Mills WY, Musso DL, Randhawa SA, Ray JA, Samano V, Frick L. Smalley TL Jr, et al. Among authors: musso dl. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6257-60. doi: 10.1016/j.bmcl.2007.09.009. Epub 2007 Sep 7. Bioorg Med Chem Lett. 2007. PMID: 17870531

5

Substrate specificity and novel selective inhibitors of TNF-alpha converting enzyme (TACE) from two-dimensional substrate mapping.

Lambert MH, Blackburn RK, Seaton TD, Kassel DB, Kinder DS, Leesnitzer MA, Bickett DM, Warner JR, Andersen MW, Badiang JG, Cowan DJ, Gaul MD, Petrov KG, Rabinowitz MH, Wiethe RW, Becherer JD, McDougald DL, Musso DL, Andrews RC, Moss ML. Lambert MH, et al. Among authors: musso dl. Comb Chem High Throughput Screen. 2005 Jun;8(4):327-39. doi: 10.2174/1386207054020840. Comb Chem High Throughput Screen. 2005. PMID: 16101009

6

Novel 3-phenylprop-2-ynylamines as inhibitors of mammalian squalene epoxidase.

Musso DL, Clarke MJ, Kelley JL, Boswell GE, Chen G. Musso DL, et al. Org Biomol Chem. 2003 Feb 7;1(3):498-506. doi: 10.1039/b209165h. Org Biomol Chem. 2003. PMID: 12926252

7

Indanylidenes. 2. Design and synthesis of (E)-2-(4-chloro-6-fluoro-1-indanylidene)-N-methylacetamide, a potent antiinflammatory and analgesic agent without centrally acting muscle relaxant activity.

Musso DL, Orr GF, Cochran FR, Kelley JL, Selph JL, Rigdon GC, Cooper BR, Jones ML. Musso DL, et al. J Med Chem. 2003 Jan 30;46(3):409-16. doi: 10.1021/jm020068k. J Med Chem. 2003. PMID: 12540240

8

Indanylidenes. 1. Design and synthesis of (E)-2-(4,6-difluoro-1-indanylidene)acetamide, a potent, centrally acting muscle relaxant with antiinflammatory and analgesic activity.

Musso DL, Cochran FR, Kelley JL, McLean EW, Selph JL, Rigdon GC, Orr GF, Davis RG, Cooper BR, Styles VL, Thompson JB, Hall WR. Musso DL, et al. J Med Chem. 2003 Jan 30;46(3):399-408. doi: 10.1021/jm020067s. J Med Chem. 2003. PMID: 12540239

9

Design of selective and soluble inhibitors of tumor necrosis factor-alpha converting enzyme (TACE).

Rabinowitz MH, Andrews RC, Becherer JD, Bickett DM, Bubacz DG, Conway JG, Cowan DJ, Gaul M, Glennon K, Lambert MH, Leesnitzer MA, McDougald DL, Moss ML, Musso DL, Rizzolio MC. Rabinowitz MH, et al. Among authors: musso dl. J Med Chem. 2001 Nov 22;44(24):4252-67. doi: 10.1021/jm0102654. J Med Chem. 2001. PMID: 11708926

10

N-hydroxyformamide peptidomimetics as TACE/matrix metalloprotease inhibitors: oral activity via P1' isobutyl substitution.

Musso DL, Andersen MW, Andrews RC, Austin R, Beaudet EJ, Becherer JD, Bubacz DG, Bickett DM, Chan JH, Conway JG, Cowan DJ, Gaul MD, Glennon KC, Hedeen KM, Lambert MH, Leesnitzer MA, McDougald DL, Mitchell JL, Moss ML, Rabinowitz MH, Rizzolio MC, Schaller LT, Stanford JB, Tippin T, Warner JR, Whitesell LG, Wiethe RW. Musso DL, et al. Bioorg Med Chem Lett. 2001 Aug 20;11(16):2147-51. doi: 10.1016/s0960-894x(01)00377-8. Bioorg Med Chem Lett. 2001. PMID: 11514157

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