Rother MB - Search Results

1

The Fanconi anemia core complex promotes CtIP-dependent end resection to drive homologous recombination at DNA double-strand breaks.

van de Kooij B, van der Wal FJ, Rother MB, Wiegant WW, Creixell P, Stout M, Joughin BA, Vornberger J, Altmeyer M, van Vugt MATM, Yaffe MB, van Attikum H. van de Kooij B, et al. Among authors: rother mb. Nat Commun. 2024 Aug 16;15(1):7076. doi: 10.1038/s41467-024-51090-6. Nat Commun. 2024. PMID: 39152113 Free PMC article.

2

The Fanconi anemia core complex promotes CtIP-dependent end-resection to drive homologous recombination at DNA double-strand breaks.

van de Kooij B, van der Wal FJ, Rother MB, Creixell P, Stout M, Wiegant W, Joughin BA, Vornberger J, van Vugt MATM, Altmeyer M, Yaffe MB, van Attikum H. van de Kooij B, et al. Among authors: rother mb. bioRxiv [Preprint]. 2023 Sep 6:2023.09.05.556391. doi: 10.1101/2023.09.05.556391. bioRxiv. 2023. Update in: Nat Commun. 2024 Aug 16;15(1):7076. doi: 10.1038/s41467-024-51090-6 PMID: 37732274 Free PMC article. Updated. Preprint.

3

HPF1-dependent histone ADP-ribosylation triggers chromatin relaxation to promote the recruitment of repair factors at sites of DNA damage.

Smith R, Zentout S, Rother M, Bigot N, Chapuis C, Mihuț A, Zobel FF, Ahel I, van Attikum H, Timinszky G, Huet S. Smith R, et al. Nat Struct Mol Biol. 2023 May;30(5):678-691. doi: 10.1038/s41594-023-00977-x. Epub 2023 Apr 27. Nat Struct Mol Biol. 2023. PMID: 37106138

4

XPC-PARP complexes engage the chromatin remodeler ALC1 to catalyze global genome DNA damage repair.

Blessing C, Apelt K, van den Heuvel D, Gonzalez-Leal C, Rother MB, van der Woude M, González-Prieto R, Yifrach A, Parnas A, Shah RG, Kuo TT, Boer DEC, Cai J, Kragten A, Kim HS, Schärer OD, Vertegaal ACO, Shah GM, Adar S, Lans H, van Attikum H, Ladurner AG, Luijsterburg MS. Blessing C, et al. Among authors: rother mb. Nat Commun. 2022 Aug 13;13(1):4762. doi: 10.1038/s41467-022-31820-4. Nat Commun. 2022. PMID: 35963869 Free PMC article.

5

Zinc finger protein ZNF384 is an adaptor of Ku to DNA during classical non-homologous end-joining.

Singh JK, Smith R, Rother MB, de Groot AJL, Wiegant WW, Vreeken K, D'Augustin O, Kim RQ, Qian H, Krawczyk PM, González-Prieto R, Vertegaal ACO, Lamers M, Huet S, van Attikum H. Singh JK, et al. Among authors: rother mb. Nat Commun. 2021 Nov 12;12(1):6560. doi: 10.1038/s41467-021-26691-0. Nat Commun. 2021. PMID: 34772923 Free PMC article.

6

A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair.

Pulver EM, Mukherjee C, van de Kamp G, Roobol SJ, Rother MB, van der Gulden H, de Bruijn R, Lattanzio MV, van der Burg E, Drenth AP, Verkaik NS, Hahn K, Klarenbeek S, de Korte-Grimmerink R, van de Ven M, Pritchard CEJ, Huijbers IJ, Xia B, van Gent DC, Essers J, van Attikum H, Ray Chaudhuri A, Bouwman P, Jonkers J. Pulver EM, et al. Among authors: rother mb. Cancer Res. 2021 Dec 15;81(24):6171-6182. doi: 10.1158/0008-5472.CAN-21-1415. Epub 2021 Sep 21. Cancer Res. 2021. PMID: 34548335 Free PMC article.

7

Poly(ADP-ribosyl)ation temporally confines SUMO-dependent ataxin-3 recruitment to control DNA double-strand break repair.

Pfeiffer A, Herzog LK, Luijsterburg MS, Shah RG, Rother MB, Stoy H, Kühbacher U, van Attikum H, Shah GM, Dantuma NP. Pfeiffer A, et al. Among authors: rother mb. J Cell Sci. 2021 Feb 8;134(3):jcs247809. doi: 10.1242/jcs.247809. J Cell Sci. 2021. PMID: 33408245

8

CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks.

Rother MB, Pellegrino S, Smith R, Gatti M, Meisenberg C, Wiegant WW, Luijsterburg MS, Imhof R, Downs JA, Vertegaal ACO, Huet S, Altmeyer M, van Attikum H. Rother MB, et al. Nat Commun. 2020 Nov 13;11(1):5775. doi: 10.1038/s41467-020-19502-5. Nat Commun. 2020. PMID: 33188175 Free PMC article.

9

Loss of ZBTB24 impairs nonhomologous end-joining and class-switch recombination in patients with ICF syndrome.

Helfricht A, Thijssen PE, Rother MB, Shah RG, Du L, Takada S, Rogier M, Moritz J, IJspeert H, Stoepker C, van Ostaijen-Ten Dam MM, Heyer V, Luijsterburg MS, de Groot A, Jak R, Grootaers G, Wang J, Rao P, Vertegaal ACO, van Tol MJD, Pan-Hammarström Q, Reina-San-Martin B, Shah GM, van der Burg M, van der Maarel SM, van Attikum H. Helfricht A, et al. Among authors: rother mb. J Exp Med. 2020 Nov 2;217(11):e20191688. doi: 10.1084/jem.20191688. J Exp Med. 2020. PMID: 32865561 Free PMC article.

10

PHF2 regulates homology-directed DNA repair by controlling the resection of DNA double strand breaks.

Alonso-de Vega I, Paz-Cabrera MC, Rother MB, Wiegant WW, Checa-Rodríguez C, Hernández-Fernaud JR, Huertas P, Freire R, van Attikum H, Smits VAJ. Alonso-de Vega I, et al. Among authors: rother mb. Nucleic Acids Res. 2020 May 21;48(9):4915-4927. doi: 10.1093/nar/gkaa196. Nucleic Acids Res. 2020. PMID: 32232336 Free PMC article.

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