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Acetylation of SAMHD1 at lysine 580 is crucial for blocking HIV-1 infection.
Bulnes-Ramos A, Schott K, Rabinowitz J, Luchsinger C, Bertelli C, Miyagi E, Yu CH, Persaud M, Shepard C, König R, Kim B, Ivanov DN, Strebel K, Diaz-Griffero F. Bulnes-Ramos A, et al. Among authors: schott k. mBio. 2024 Sep 11;15(9):e0195824. doi: 10.1128/mbio.01958-24. Epub 2024 Aug 20. mBio. 2024. PMID: 39162568 Free PMC article.
Gene editing of SAMHD1 in macrophage-like cells reveals complex relationships between SAMHD1 phospho-regulation, HIV-1 restriction and cellular dNTP levels.
Schüssler M, Schott K, Fuchs NV, Oo A, Zahadi M, Rauch P, Kim B, König R. Schüssler M, et al. Among authors: schott k. bioRxiv [Preprint]. 2023 Aug 25:2023.08.24.554731. doi: 10.1101/2023.08.24.554731. bioRxiv. 2023. Update in: mBio. 2023 Oct 31;14(5):e0225223. doi: 10.1128/mbio.02252-23. PMID: 37662193 Free PMC article. Updated. Preprint.
Restrictive influence of SAMHD1 on Hepatitis B Virus life cycle.
Sommer AF, Rivière L, Qu B, Schott K, Riess M, Ni Y, Shepard C, Schnellbächer E, Finkernagel M, Himmelsbach K, Welzel K, Kettern N, Donnerhak C, Münk C, Flory E, Liese J, Kim B, Urban S, König R. Sommer AF, et al. Among authors: schott k. Sci Rep. 2016 May 27;6:26616. doi: 10.1038/srep26616. Sci Rep. 2016. PMID: 27229711 Free PMC article.
Role of Innate Genes in HIV Replication.
Schott K, Riess M, König R. Schott K, et al. Curr Top Microbiol Immunol. 2018;419:69-111. doi: 10.1007/82_2017_29. Curr Top Microbiol Immunol. 2018. PMID: 28685292 Review.
SAMHD1 in cancer: curse or cure?
Schott K, Majer C, Bulashevska A, Childs L, Schmidt MHH, Rajalingam K, Munder M, König R. Schott K, et al. J Mol Med (Berl). 2022 Mar;100(3):351-372. doi: 10.1007/s00109-021-02131-w. Epub 2021 Sep 4. J Mol Med (Berl). 2022. PMID: 34480199 Free PMC article. Review.
USP18 (UBP43) Abrogates p21-Mediated Inhibition of HIV-1.
Osei Kuffour E, Schott K, Jaguva Vasudevan AA, Holler J, Schulz WA, Lang PA, Lang KS, Kim B, Häussinger D, König R, Münk C. Osei Kuffour E, et al. Among authors: schott k. J Virol. 2018 Sep 26;92(20):e00592-18. doi: 10.1128/JVI.00592-18. Print 2018 Oct 15. J Virol. 2018. PMID: 30068654 Free PMC article.
126 results