Esser-Kahn AP - Search Results

1

Identification of CDK4/6 Inhibitors as Small Molecule NLRP3 Inflammasome Activators that Facilitate IL-1β Secretion and T Cell Adjuvanticity.

Weiss AM, Lopez MA 2nd, Rosenberger MG, Kim JY, Shen J, Chen Q, Ung T, Ibeh UM, Knight HR, Rutledge NS, Studnitzer B, Rowan SJ, Esser-Kahn AP. Weiss AM, et al. Among authors: esser kahn ap. J Med Chem. 2024 Sep 12;67(17):14974-14985. doi: 10.1021/acs.jmedchem.4c00516. Epub 2024 Aug 20. J Med Chem. 2024. PMID: 39162654

2

Immunomodulation of the NLRP3 Inflammasome through Structure-Based Activator Design and Functional Regulation via Lysosomal Rupture.

Manna S, Howitz WJ, Oldenhuis NJ, Eldredge AC, Shen J, Nihesh FN, Lodoen MB, Guan Z, Esser-Kahn AP. Manna S, et al. ACS Cent Sci. 2018 Aug 22;4(8):982-995. doi: 10.1021/acscentsci.8b00218. Epub 2018 Jul 2. ACS Cent Sci. 2018. PMID: 30159395 Free PMC article.

3

Correction to "Immunomodulation of the NLRP3 Inflammasome through Structure-Based Activator Design and Functional Regulation via Lysosomal Rupture".

Manna S, Howitz WJ, Oldenhuis NJ, Eldredge AC, Shen J, Nihesh FN, Lodoen MB, Guan Z, Esser-Kahn AP. Manna S, et al. ACS Cent Sci. 2018 Nov 28;4(11):1593. doi: 10.1021/acscentsci.8b00752. Epub 2018 Oct 31. ACS Cent Sci. 2018. PMID: 30555913 Free PMC article.

4

Mitigation of Hydrophobicity-Induced Immunotoxicity by Sugar Poly(orthoesters).

Maiti S, Manna S, Shen J, Esser-Kahn AP, Du W. Maiti S, et al. J Am Chem Soc. 2019 Mar 20;141(11):4510-4514. doi: 10.1021/jacs.8b12205. Epub 2019 Feb 25. J Am Chem Soc. 2019. PMID: 30768257 Free PMC article.

5

Increased vaccine tolerability and protection via NF-κB modulation.

Moser BA, Steinhardt RC, Escalante-Buendia Y, Boltz DA, Barker KM, Cassaidy BJ, Rosenberger MG, Yoo S, McGonnigal BG, Esser-Kahn AP. Moser BA, et al. Sci Adv. 2020 Sep 9;6(37):eaaz8700. doi: 10.1126/sciadv.aaz8700. Print 2020 Sep. Sci Adv. 2020. PMID: 32917696 Free PMC article.

6

Small Molecule NF-κB Inhibitors as Immune Potentiators for Enhancement of Vaccine Adjuvants.

Moser BA, Escalante-Buendia Y, Steinhardt RC, Rosenberger MG, Cassaidy BJ, Naorem N, Chon AC, Nguyen MH, Tran NT, Esser-Kahn AP. Moser BA, et al. Front Immunol. 2020 Sep 25;11:511513. doi: 10.3389/fimmu.2020.511513. eCollection 2020. Front Immunol. 2020. PMID: 33072085 Free PMC article.

7

Pathogen-like Nanoassemblies of Covalently Linked TLR Agonists Enhance CD8 and NK Cell-Mediated Antitumor Immunity.

Manna S, Maiti S, Shen J, Du W, Esser-Kahn AP. Manna S, et al. ACS Cent Sci. 2020 Nov 25;6(11):2071-2078. doi: 10.1021/acscentsci.0c01001. Epub 2020 Oct 27. ACS Cent Sci. 2020. PMID: 33274283 Free PMC article.

8

In Vitro and in Vivo Analyses of the Effects of Source, Length, and Charge on the Cytotoxicity and Immunocompatibility of Cellulose Nanocrystals.

Weiss AM, Macke N, Zhang Y, Calvino C, Esser-Kahn AP, Rowan SJ. Weiss AM, et al. ACS Biomater Sci Eng. 2021 Apr 12;7(4):1450-1461. doi: 10.1021/acsbiomaterials.0c01618. Epub 2021 Mar 9. ACS Biomater Sci Eng. 2021. PMID: 33689287 Free PMC article.

9

Site-specific antigen-adjuvant conjugation using cell-free protein synthesis enhances antigen presentation and CD8⁺ T-cell response.

Weiss AM, Ajit J, Albin TJ, Kapoor N, Maroju S, Berges A, Pill L, Fairman J, Esser-Kahn AP. Weiss AM, et al. Sci Rep. 2021 Mar 18;11(1):6267. doi: 10.1038/s41598-021-85709-1. Sci Rep. 2021. PMID: 33737644 Free PMC article.

10

A synthetic pathogen mimetic molecule induces a highly amplified synergistic immune response via activation of multiple signaling pathways.

Nihesh N, Manna S, Studnitzer B, Shen J, Esser-Kahn AP. Nihesh N, et al. Chem Sci. 2021 Apr 1;12(19):6646-6651. doi: 10.1039/d1sc00964h. Chem Sci. 2021. PMID: 34040739 Free PMC article.

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