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Identification of CDK4/6 Inhibitors as Small Molecule NLRP3 Inflammasome Activators that Facilitate IL-1β Secretion and T Cell Adjuvanticity.
Weiss AM, Lopez MA 2nd, Rosenberger MG, Kim JY, Shen J, Chen Q, Ung T, Ibeh UM, Knight HR, Rutledge NS, Studnitzer B, Rowan SJ, Esser-Kahn AP. Weiss AM, et al. Among authors: lopez ma 2nd. J Med Chem. 2024 Sep 12;67(17):14974-14985. doi: 10.1021/acs.jmedchem.4c00516. Epub 2024 Aug 20. J Med Chem. 2024. PMID: 39162654