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Page 1
Fish-hunting cone snail disrupts prey's glucose homeostasis with weaponized mimetics of somatostatin and insulin.
Yeung HY, Ramiro IBL, Andersen DB, Koch TL, Hamilton A, Bjørn-Yoshimoto WE, Espino S, Vakhrushev SY, Pedersen KB, de Haan N, Hipgrave Ederveen AL, Olivera BM, Knudsen JG, Bräuner-Osborne H, Schjoldager KT, Holst JJ, Safavi-Hemami H. Yeung HY, et al. Among authors: bjorn yoshimoto we. Nat Commun. 2024 Aug 20;15(1):6408. doi: 10.1038/s41467-024-50470-2. Nat Commun. 2024. PMID: 39164229 Free PMC article.
Venom-inspired somatostatin receptor 4 (SSTR4) agonists as new drug leads for peripheral pain conditions.
Bjørn-Yoshimoto WE, Ramiro IBL, Koch TL, Engholm E, Yeung HY, Sørensen KK, Goddard CM, Jensen KL, Smith NA, Martin LF, Smith BJ, Madsen KL, Jensen KJ, Patwardhan A, Safavi-Hemami H. Bjørn-Yoshimoto WE, et al. bioRxiv [Preprint]. 2024 Apr 30:2024.04.29.591104. doi: 10.1101/2024.04.29.591104. bioRxiv. 2024. PMID: 38746149 Free PMC article. Preprint.
Ligand selectivity hotspots in serotonin GPCRs.
Simon IA, Bjørn-Yoshimoto WE, Harpsøe K, Iliadis S, Svensson B, Jensen AA, Gloriam DE. Simon IA, et al. Among authors: bjorn yoshimoto we. Trends Pharmacol Sci. 2023 Dec;44(12):978-990. doi: 10.1016/j.tips.2023.09.012. Epub 2023 Oct 31. Trends Pharmacol Sci. 2023. PMID: 37914598 Free article. Review.
(S)-2-Mercaptohistidine: A First Selective Orthosteric GluK3 Antagonist.
Poulie CBM, Larsen Y, Leteneur C, Barthet G, Bjørn-Yoshimoto WE, Malhaire F, Nielsen B, Pin JP, Mulle C, Pickering DS, Bunch L. Poulie CBM, et al. Among authors: bjorn yoshimoto we. ACS Chem Neurosci. 2022 May 18;13(10):1580-1587. doi: 10.1021/acschemneuro.2c00162. Epub 2022 Apr 27. ACS Chem Neurosci. 2022. PMID: 35475632
Somatostatin venom analogs evolved by fish-hunting cone snails: From prey capture behavior to identifying drug leads.
Ramiro IBL, Bjørn-Yoshimoto WE, Imperial JS, Gajewiak J, Salcedo PF, Watkins M, Taylor D, Resager W, Ueberheide B, Bräuner-Osborne H, Whitby FG, Hill CP, Martin LF, Patwardhan A, Concepcion GP, Olivera BM, Safavi-Hemami H. Ramiro IBL, et al. Among authors: bjorn yoshimoto we. Sci Adv. 2022 Mar 25;8(12):eabk1410. doi: 10.1126/sciadv.abk1410. Epub 2022 Mar 23. Sci Adv. 2022. PMID: 35319982 Free PMC article.
Design and Synthesis of 2,3- trans-Proline Analogues as Ligands for Ionotropic Glutamate Receptors and Excitatory Amino Acid Transporters.
Poulie CBM, Alcaide A, Krell-Jørgensen M, Larsen Y, Astier E, Bjørn-Yoshimoto WE, Yi F, Syrenne JT, Storgaard M, Nielsen B, Frydenvang KA, Jensen AA, Hansen KB, Pickering DS, Bunch L. Poulie CBM, et al. Among authors: bjorn yoshimoto we. ACS Chem Neurosci. 2019 Jun 19;10(6):2989-3007. doi: 10.1021/acschemneuro.9b00205. Epub 2019 May 24. ACS Chem Neurosci. 2019. PMID: 31124660 Free PMC article.
5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology.
Peng Y, McCorvy JD, Harpsøe K, Lansu K, Yuan S, Popov P, Qu L, Pu M, Che T, Nikolajsen LF, Huang XP, Wu Y, Shen L, Bjørn-Yoshimoto WE, Ding K, Wacker D, Han GW, Cheng J, Katritch V, Jensen AA, Hanson MA, Zhao S, Gloriam DE, Roth BL, Stevens RC, Liu ZJ. Peng Y, et al. Among authors: bjorn yoshimoto we. Cell. 2018 Feb 8;172(4):719-730.e14. doi: 10.1016/j.cell.2018.01.001. Epub 2018 Feb 1. Cell. 2018. PMID: 29398112 Free PMC article.
19 results