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A 'double-edged' role for type-5 metabotropic glutamate receptors in pain disclosed by light-sensitive drugs.
Notartomaso S, Antenucci N, Mazzitelli M, Rovira X, Boccella S, Ricciardi F, Liberatore F, Gomez-Santacana X, Imbriglio T, Cannella M, Zussy C, Luongo L, Maione S, Goudet C, Battaglia G, Llebaria A, Nicoletti F, Neugebauer V. Notartomaso S, et al. Elife. 2024 Aug 22;13:e94931. doi: 10.7554/eLife.94931. Elife. 2024. PMID: 39172042 Free PMC article.
Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator.
Font J, López-Cano M, Notartomaso S, Scarselli P, Di Pietro P, Bresolí-Obach R, Battaglia G, Malhaire F, Rovira X, Catena J, Giraldo J, Pin JP, Fernández-Dueñas V, Goudet C, Nonell S, Nicoletti F, Llebaria A, Ciruela F. Font J, et al. Among authors: notartomaso s. Elife. 2017 Apr 11;6:e23545. doi: 10.7554/eLife.23545. Elife. 2017. PMID: 28395733 Free PMC article.
Perineuronal nets are under the control of type-5 metabotropic glutamate receptors in the developing somatosensory cortex.
Mascio G, Bucci D, Notartomaso S, Liberatore F, Antenucci N, Scarselli P, Imbriglio T, Caruso S, Gradini R, Cannella M, Di Menna L, Bruno V, Battaglia G, Nicoletti F. Mascio G, et al. Among authors: notartomaso s. Transl Psychiatry. 2021 Feb 18;11(1):109. doi: 10.1038/s41398-021-01210-3. Transl Psychiatry. 2021. PMID: 33597513 Free PMC article.
Light-Induced Activation of a Specific Type-5 Metabotropic Glutamate Receptor Antagonist in the Ventrobasal Thalamus Causes Analgesia in a Mouse Model of Breakthrough Cancer Pain.
Notartomaso S, Antenucci N, Liberatore F, Mascio G, Boccadamo Pompili SV, Font J, Scioli M, Luongo L, Arcella A, Gradini R, Llebaria A, Nicoletti F. Notartomaso S, et al. Int J Mol Sci. 2022 Jul 20;23(14):8018. doi: 10.3390/ijms23148018. Int J Mol Sci. 2022. PMID: 35887364 Free PMC article.
A "double-edged" role for type-5 metabotropic glutamate receptors in pain disclosed by light-sensitive drugs.
Notartomaso S, Antenucci N, Mazzitelli M, Rovira X, Boccella S, Ricciardi F, Liberatore F, Gomez-Santacana X, Imbriglio T, Cannella M, Zussy C, Luongo L, Maione S, Goudet C, Battaglia G, Llebaria A, Nicoletti F, Neugebauer V. Notartomaso S, et al. bioRxiv [Preprint]. 2024 Jan 3:2024.01.02.573945. doi: 10.1101/2024.01.02.573945. bioRxiv. 2024. Update in: Elife. 2024 Aug 22;13:e94931. doi: 10.7554/eLife.94931 PMID: 38260426 Free PMC article. Updated. Preprint.
Pharmacological enhancement of mGlu1 metabotropic glutamate receptors causes a prolonged symptomatic benefit in a mouse model of spinocerebellar ataxia type 1.
Notartomaso S, Zappulla C, Biagioni F, Cannella M, Bucci D, Mascio G, Scarselli P, Fazio F, Weisz F, Lionetto L, Simmaco M, Gradini R, Battaglia G, Signore M, Puliti A, Nicoletti F. Notartomaso S, et al. Mol Brain. 2013 Nov 19;6:48. doi: 10.1186/1756-6606-6-48. Mol Brain. 2013. PMID: 24252411 Free PMC article.
26 results