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Design and Optimization of Selectivity-Tunable Toll-like Receptor 7/8 Agonists as Novel Antibody-Drug Conjugate Payloads.
Patel AM, Willingham A, Cheng AC, Tomazela D, Bowman E, Kofman E, Zhang F, Bao J, Sanzone JR, Choy JW, Flygare JA, Han JH, Pradhan K, Kieffer M, Chernyak N, Akbari P, Liu P, Mehmood R, Naravula S, Hollingsworth SA, Bhagwat B, Lang SB, Seganish WM. Patel AM, et al. Among authors: chernyak n. J Med Chem. 2024 Sep 12;67(17):15756-15779. doi: 10.1021/acs.jmedchem.4c01384. Epub 2024 Aug 22. J Med Chem. 2024. PMID: 39172064
Tip-Directed Synthesis of Multimetallic Nanoparticles.
Chen PC, Liu G, Zhou Y, Brown KA, Chernyak N, Hedrick JL, He S, Xie Z, Lin QY, Dravid VP, O'Neill-Slawecki SA, Mirkin CA. Chen PC, et al. Among authors: chernyak n. J Am Chem Soc. 2015 Jul 22;137(28):9167-73. doi: 10.1021/jacs.5b05139. Epub 2015 Jul 6. J Am Chem Soc. 2015. PMID: 26144242
Direct Pd-catalyzed arylation of 1,2,3-triazoles.
Chuprakov S, Chernyak N, Dudnik AS, Gevorgyan V. Chuprakov S, et al. Among authors: chernyak n. Org Lett. 2007 Jun 7;9(12):2333-6. doi: 10.1021/ol070697u. Epub 2007 May 10. Org Lett. 2007. PMID: 17489598 Free PMC article.
Discovery and Evaluation of TLR-Targeted Immune Agonists.
Chernyak N, Bhagwat B, Naravula S, Chen Y, Solban N, Zhang F, Kofman E, Raoufi F, Dang X, Bao J, Tomazela D, Baily M, Geierstanger B, Flygare JA, Han JH, Willingham A, Seganish WM. Chernyak N, et al. J Med Chem. 2024 Sep 26;67(18):16222-16234. doi: 10.1021/acs.jmedchem.4c00804. Epub 2024 Sep 5. J Med Chem. 2024. PMID: 39235949
78 results