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Fragment-Based Interrogation of the 14-3-3/TAZ Protein-Protein Interaction.
Andlovic B, Valenti D, Centorrino F, Picarazzi F, Hristeva S, Hiltmann M, Wolf A, Cantrelle FX, Mori M, Landrieu I, Levy LM, Klebl B, Tzalis D, Genski T, Eickhoff J, Ottmann C. Andlovic B, et al. Among authors: cantrelle fx. Biochemistry. 2024 Sep 3;63(17):2196-2206. doi: 10.1021/acs.biochem.4c00248. Epub 2024 Aug 22. Biochemistry. 2024. PMID: 39172504 Free PMC article.
Set-up and screening of a fragment library targeting the 14-3-3 protein interface.
Valenti D, Neves JF, Cantrelle FX, Hristeva S, Lentini Santo D, Obšil T, Hanoulle X, Levy LM, Tzalis D, Landrieu I, Ottmann C. Valenti D, et al. Among authors: cantrelle fx. Medchemcomm. 2019 Jul 22;10(10):1796-1802. doi: 10.1039/c9md00215d. eCollection 2019 Oct 1. Medchemcomm. 2019. PMID: 31814953 Free PMC article.
A β-Turn Motif in the Steroid Hormone Receptor's Ligand-Binding Domains Interacts with the Peptidyl-prolyl Isomerase (PPIase) Catalytic Site of the Immunophilin FKBP52.
Byrne C, Henen MA, Belnou M, Cantrelle FX, Kamah A, Qi H, Giustiniani J, Chambraud B, Baulieu EE, Lippens G, Landrieu I, Jacquot Y. Byrne C, et al. Among authors: cantrelle fx. Biochemistry. 2016 Sep 27;55(38):5366-76. doi: 10.1021/acs.biochem.6b00506. Epub 2016 Sep 19. Biochemistry. 2016. PMID: 27641460
NMR Spectroscopy of the Main Protease of SARS-CoV-2 and Fragment-Based Screening Identify Three Protein Hotspots and an Antiviral Fragment.
Cantrelle FX, Boll E, Brier L, Moschidi D, Belouzard S, Landry V, Leroux F, Dewitte F, Landrieu I, Dubuisson J, Deprez B, Charton J, Hanoulle X. Cantrelle FX, et al. Angew Chem Int Ed Engl. 2021 Nov 22;60(48):25428-25435. doi: 10.1002/anie.202109965. Epub 2021 Oct 27. Angew Chem Int Ed Engl. 2021. PMID: 34570415 Free PMC article.
69 results