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In pancreatic cancer patients, chemotherapy reshapes the gene expression profile and antigen receptor repertoire of T lymphocytes and enhances their effector response to tumor-associated antigens.
Brugiapaglia S, Bulfamante S, Curcio C, Arigoni M, Calogero R, Bonello L, Genuardi E, Spadi R, Satolli MA, Campra D, Giordano D, Cappello P, Cordero F, Novelli F. Brugiapaglia S, et al. Among authors: novelli f. Front Immunol. 2024 Aug 8;15:1427424. doi: 10.3389/fimmu.2024.1427424. eCollection 2024. Front Immunol. 2024. PMID: 39176093 Free PMC article.
Alpha-Enolase (ENO1), a potential target in novel immunotherapies.
Cappello P, Principe M, Bulfamante S, Novelli F. Cappello P, et al. Among authors: novelli f. Front Biosci (Landmark Ed). 2017 Jan 1;22(5):944-959. doi: 10.2741/4526. Front Biosci (Landmark Ed). 2017. PMID: 27814656 Free article. Review.
In pancreatic cancer, chemotherapy increases antitumor responses to tumor-associated antigens and potentiates DNA vaccination.
Mandili G, Curcio C, Bulfamante S, Follia L, Ferrero G, Mazza E, Principe M, Cordero F, Satolli MA, Spadi R, Evangelista A, Giordano D, Viet D, Cappello P, Novelli F. Mandili G, et al. Among authors: novelli f. J Immunother Cancer. 2020 Oct;8(2):e001071. doi: 10.1136/jitc-2020-001071. J Immunother Cancer. 2020. PMID: 33115943 Free PMC article.
A self antigen reopens the games in pancreatic cancer.
Cappello P, Novelli F. Cappello P, et al. Among authors: novelli f. Oncoimmunology. 2013 Jun 1;2(6):e24384. doi: 10.4161/onci.24384. Epub 2013 May 10. Oncoimmunology. 2013. PMID: 23894698 Free PMC article.
Intra-tumoral IFN-γ-producing Th22 cells correlate with TNM staging and the worst outcomes in pancreatic cancer.
Niccolai E, Taddei A, Ricci F, Rolla S, D'Elios MM, Benagiano M, Bechi P, Bencini L, Ringressi MN, Pini A, Castiglione F, Giordano D, Satolli MA, Coratti A, Cianchi F, Bani D, Prisco D, Novelli F, Amedei A. Niccolai E, et al. Among authors: novelli f. Clin Sci (Lond). 2016 Feb;130(4):247-58. doi: 10.1042/CS20150437. Epub 2015 Nov 20. Clin Sci (Lond). 2016. PMID: 26590104
Alpha-enolase (ENO1) controls alpha v/beta 3 integrin expression and regulates pancreatic cancer adhesion, invasion, and metastasis.
Principe M, Borgoni S, Cascione M, Chattaragada MS, Ferri-Borgogno S, Capello M, Bulfamante S, Chapelle J, Di Modugno F, Defilippi P, Nisticò P, Cappello P, Riganti C, Leporatti S, Novelli F. Principe M, et al. Among authors: novelli f. J Hematol Oncol. 2017 Jan 13;10(1):16. doi: 10.1186/s13045-016-0385-8. J Hematol Oncol. 2017. PMID: 28086938 Free PMC article.
Immune-Complexome Analysis Identifies Immunoglobulin-Bound Biomarkers That Predict the Response to Chemotherapy of Pancreatic Cancer Patients.
Mandili G, Follia L, Ferrero G, Katayama H, Hong W, Momin AA, Capello M, Giordano D, Spadi R, Satolli MA, Evangelista A, Hanash SM, Cordero F, Novelli F. Mandili G, et al. Among authors: novelli f. Cancers (Basel). 2020 Mar 21;12(3):746. doi: 10.3390/cancers12030746. Cancers (Basel). 2020. PMID: 32245227 Free PMC article.
310 results