Ruan GX - Search Results

1

Suppression of HSV-1 infection and viral reactivation by CRISPR-Cas9 gene editing in 2D and 3D culture models.

Bellizzi A, Çakır S, Donadoni M, Sariyer R, Liao S, Liu H, Ruan GX, Gordon J, Khalili K, Sariyer IK. Bellizzi A, et al. Among authors: ruan gx. Mol Ther Nucleic Acids. 2024 Jul 19;35(3):102282. doi: 10.1016/j.omtn.2024.102282. eCollection 2024 Sep 10. Mol Ther Nucleic Acids. 2024. PMID: 39176174 Free PMC article.

2

CRISPR/Cas9-Mediated Genome Editing as a Therapeutic Approach for Leber Congenital Amaurosis 10.

Ruan GX, Barry E, Yu D, Lukason M, Cheng SH, Scaria A. Ruan GX, et al. Mol Ther. 2017 Feb 1;25(2):331-341. doi: 10.1016/j.ymthe.2016.12.006. Epub 2017 Jan 18. Mol Ther. 2017. PMID: 28109959 Free PMC article.

3

CRISPR-Cas9-mediated genome editing delivered by a single AAV9 vector inhibits HSV-1 reactivation in a latent rabbit keratitis model.

Amrani N, Luk K, Singh P, Shipley M, Isik M, Donadoni M, Bellizzi A, Khalili K, Sariyer IK, Neumann D, Gordon J, Ruan GX. Amrani N, et al. Among authors: ruan gx. Mol Ther Methods Clin Dev. 2024 Aug 14;32(3):101303. doi: 10.1016/j.omtm.2024.101303. eCollection 2024 Sep 12. Mol Ther Methods Clin Dev. 2024. PMID: 39610766 Free PMC article.

4

Spliceosome component PHD finger 5A is essential for early B lymphopoiesis.

Zhang R, Wang D, Ruan GX, Wang R, Li Y, Chen W, Huang H, Wang J, Meng L, Zhu Z, Lei D, Xu S, Ou X. Zhang R, et al. Among authors: ruan gx. Development. 2024 Jan 15;151(2):dev202247. doi: 10.1242/dev.202247. Epub 2024 Jan 11. Development. 2024. PMID: 38095286

5

The histone H2B ubiquitination regulator Wac is essential for plasma cell differentiation.

Li Y, Ruan GX, Chen W, Huang H, Zhang R, Wang J, Ouyang Y, Zhu Z, Meng L, Wang R, Huo J, Xu S, Ou X. Li Y, et al. Among authors: ruan gx. FEBS Lett. 2023 Jul;597(13):1748-1760. doi: 10.1002/1873-3468.14633. Epub 2023 May 23. FEBS Lett. 2023. PMID: 37171241 Free article.

6

The RNA-binding protein hnRNP F is required for the germinal center B cell response.

Huang H, Li Y, Zhang G, Ruan GX, Zhu Z, Chen W, Zou J, Zhang R, Wang J, Ouyang Y, Xu S, Ou X. Huang H, et al. Among authors: ruan gx. Nat Commun. 2023 Mar 30;14(1):1731. doi: 10.1038/s41467-023-37308-z. Nat Commun. 2023. PMID: 36997512 Free PMC article.

7

Adenosine deaminase acting on RNA-1 is essential for early B lymphopoiesis.

Chen W, Li Y, Ruan GX, Huang H, Zhang R, Wang J, Ouyang Y, Li Y, Xu S, Ou X. Chen W, et al. Among authors: ruan gx. Cell Rep. 2022 Nov 22;41(8):111687. doi: 10.1016/j.celrep.2022.111687. Cell Rep. 2022. PMID: 36417848 Free article.

8

RNA-Editing Enzyme ADAR1 p150 Isoform Is Critical for Germinal Center B Cell Response.

Li Y, Ruan GX, Chen W, Huang H, Zhang R, Wang J, Li Y, Xu S, Ou X. Li Y, et al. Among authors: ruan gx. J Immunol. 2022 Sep 15;209(6):1071-1082. doi: 10.4049/jimmunol.2200149. Epub 2022 Aug 17. J Immunol. 2022. PMID: 35977796

9

Mettl14-Mediated m6A Modification Is Essential for Germinal Center B Cell Response.

Huang H, Zhang G, Ruan GX, Li Y, Chen W, Zou J, Zhang R, Wang J, Ji SJ, Xu S, Ou X. Huang H, et al. Among authors: ruan gx. J Immunol. 2022 Apr 15;208(8):1924-1936. doi: 10.4049/jimmunol.2101071. Epub 2022 Apr 1. J Immunol. 2022. PMID: 35365563

10

The spliceosome component Usp39 controls B cell development by regulating immunoglobulin gene rearrangement.

Ruan GX, Li Y, Chen W, Huang H, Zhang R, Chen C, Lam KP, Xu S, Ou X. Ruan GX, et al. Cell Rep. 2022 Feb 8;38(6):110338. doi: 10.1016/j.celrep.2022.110338. Cell Rep. 2022. PMID: 35139388 Free article.

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