Ryu JS - Search Results

1

Exploring novel A_2AAR antagonists: Design, synthesis, and evaluation of 2,6,9-trisubstituted purine derivatives as promising antifibrotic agents.

Sun J, Kim S, Park S, Hwang S, Sheen N, Kim S, Kwon Y, Ryu JS. Sun J, et al. Among authors: ryu js. Bioorg Med Chem. 2024 Oct 1;112:117881. doi: 10.1016/j.bmc.2024.117881. Epub 2024 Aug 16. Bioorg Med Chem. 2024. PMID: 39178585

2

Design, synthesis, and biological evaluation of novel constrained meta-substituted phenyl propanoic acids as peroxisome proliferator-activated receptor alpha and gamma dual agonists.

Suh YG, Kim NJ, Koo BW, Lee KO, Moon SH, Shin DH, Jung JW, Paek SM, Chang DJ, Li F, Kang HJ, Le TV, Chae YN, Shin CY, Kim MK, Lim JI, Ryu JS, Park HJ. Suh YG, et al. Among authors: ryu js. J Med Chem. 2008 Oct 23;51(20):6318-33. doi: 10.1021/jm8003416. Epub 2008 Oct 1. J Med Chem. 2008. PMID: 18826205

3

Synthesis and biological evaluation of 1-(6-methylpyridin-2-yl)-5-(quinoxalin-6-yl)-1,2,3-triazoles as transforming growth factor-β type 1 receptor kinase inhibitors.

Li F, Park Y, Hah JM, Ryu JS. Li F, et al. Among authors: ryu js. Bioorg Med Chem Lett. 2013 Feb 15;23(4):1083-6. doi: 10.1016/j.bmcl.2012.12.008. Epub 2012 Dec 20. Bioorg Med Chem Lett. 2013. PMID: 23294702

4

Design, synthesis and biological evaluation of benzyl 2-(1H-imidazole-1-yl) pyrimidine analogues as selective and potent Raf inhibitors.

Kim M, Lee J, Jung K, Kim H, Aman W, Ryu JS, Hah JM. Kim M, et al. Among authors: ryu js. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3600-4. doi: 10.1016/j.bmcl.2014.05.030. Epub 2014 May 17. Bioorg Med Chem Lett. 2014. PMID: 24878193

5

Click approach to the discovery of 1,2,3-triazolylsalicylamides as potent Aurora kinase inhibitors.

Song D, Park Y, Yoon J, Aman W, Hah JM, Ryu JS. Song D, et al. Among authors: ryu js. Bioorg Med Chem. 2014 Sep 1;22(17):4855-66. doi: 10.1016/j.bmc.2014.06.047. Epub 2014 Jun 30. Bioorg Med Chem. 2014. PMID: 25042560

6

Synthesis of stereochemically diverse cyclic analogs of tubulysins.

Park Y, Bae SY, Hah JM, Lee SK, Ryu JS. Park Y, et al. Among authors: ryu js. Bioorg Med Chem. 2015 Nov 1;23(21):6827-43. doi: 10.1016/j.bmc.2015.10.003. Epub 2015 Oct 9. Bioorg Med Chem. 2015. PMID: 26474666

7

Design, synthesis, and evaluation of hinge-binder tethered 1,2,3-triazolylsalicylamide derivatives as Aurora kinase inhibitors.

Jeong Y, Lee J, Ryu JS. Jeong Y, et al. Among authors: ryu js. Bioorg Med Chem. 2016 May 1;24(9):2114-24. doi: 10.1016/j.bmc.2016.03.042. Epub 2016 Mar 25. Bioorg Med Chem. 2016. PMID: 27041399

8

A novel A2a adenosine receptor inhibitor effectively mitigates hepatic fibrosis in a metabolic dysfunction-associated steatohepatitis mouse model.

Park S, Hwang S, Sun J, Jeon KH, Sheen N, Shin S, Kim TH, Lee YS, Seo W, Ryu JS, Kwon Y. Park S, et al. Among authors: ryu js. Int J Biol Sci. 2024 Mar 3;20(5):1855-1870. doi: 10.7150/ijbs.92371. eCollection 2024. Int J Biol Sci. 2024. PMID: 38481815 Free PMC article.

9

A rapid synthesis of lavendustin-mimetic small molecules by click fragment assembly.

Yoon J, Ryu JS. Yoon J, et al. Among authors: ryu js. Bioorg Med Chem Lett. 2010 Jul 1;20(13):3930-5. doi: 10.1016/j.bmcl.2010.05.014. Epub 2010 May 12. Bioorg Med Chem Lett. 2010. PMID: 20570145

10

Syntheses of 1,2,3-triazolyl salicylamides with inhibitory activity on lipopolysaccharide-induced nitric oxide production.

Yoon J, Cho L, Lee SK, Ryu JS. Yoon J, et al. Among authors: ryu js. Bioorg Med Chem Lett. 2011 Apr 1;21(7):1953-7. doi: 10.1016/j.bmcl.2011.02.034. Epub 2011 Feb 13. Bioorg Med Chem Lett. 2011. PMID: 21377876

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