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Page 1
Identification of FDA-approved drugs that induce heart regeneration in mammals.
Ahmed MS, Nguyen NUN, Nakada Y, Hsu CC, Farag A, Lam NT, Wang P, Thet S, Menendez-Montes I, Elhelaly WM, Lou X, Secco I, Tomczyk M, Zentilin L, Pei J, Cui M, Dos Santos M, Liu X, Liu Y, Zaha D, Walcott G, Tomchick DR, Xing C, Zhang CC, Grishin NV, Giacca M, Zhang J, Sadek HA. Ahmed MS, et al. Among authors: elhelaly wm. Nat Cardiovasc Res. 2024 Mar;3(3):372-388. doi: 10.1038/s44161-024-00450-y. Epub 2024 Mar 11. Nat Cardiovasc Res. 2024. PMID: 39183959 Free PMC article.
Adducin Regulates Sarcomere Disassembly During Cardiomyocyte Mitosis.
Xiao F, Nguyen NUN, Wang P, Li S, Hsu CC, Thet S, Kimura W, Luo X, Lam NT, Menendez-Montes I, Elhelaly WM, Cardoso AC, Pereira AHM, Singh R, Sadayappan S, Kanchwala M, Xing C, Ladha FA, Hinson JT, Hajjar RJ, Hill JA, Sadek HA. Xiao F, et al. Among authors: elhelaly wm. Circulation. 2024 Sep 3;150(10):791-805. doi: 10.1161/CIRCULATIONAHA.122.059102. Epub 2024 May 6. Circulation. 2024. PMID: 38708635
Targeting calcineurin induces cardiomyocyte proliferation in adult mice.
Lam NT, Nguyen NUN, Ahmed MS, Hsu CC, Rios Coronado PE, Li S, Menendez-Montes I, Thet S, Elhelaly WM, Xiao F, Wang X, Williams NS, Canseco DC, Red-Horse K, Rothermel BA, Sadek HA. Lam NT, et al. Among authors: elhelaly wm. Nat Cardiovasc Res. 2022 Jul;1(7):679-688. doi: 10.1038/s44161-022-00098-6. Epub 2022 Jul 13. Nat Cardiovasc Res. 2022. PMID: 39196243
PKM1 Exerts Critical Roles in Cardiac Remodeling Under Pressure Overload in the Heart.
Li Q, Li C, Elnwasany A, Sharma G, An YA, Zhang G, Elhelaly WM, Lin J, Gong Y, Chen G, Wang M, Zhao S, Dai C, Smart CD, Liu J, Luo X, Deng Y, Tan L, Lv SJ, Davidson SM, Locasale JW, Lorenzi PL, Malloy CR, Gillette TG, Vander Heiden MG, Scherer PE, Szweda LI, Fu G, Wang ZV. Li Q, et al. Among authors: elhelaly wm. Circulation. 2021 Aug 31;144(9):712-727. doi: 10.1161/CIRCULATIONAHA.121.054885. Epub 2021 Jun 9. Circulation. 2021. PMID: 34102853 Free PMC article.
Mitochondrial Substrate Utilization Regulates Cardiomyocyte Cell Cycle Progression.
Cardoso AC, Lam NT, Savla JJ, Nakada Y, Pereira AHM, Elnwasany A, Menendez-Montes I, Ensley EL, Petric UB, Sharma G, Sherry AD, Malloy CR, Khemtong C, Kinter MT, Tan WLW, Anene-Nzelu CG, Foo RS, Nguyen NUN, Li S, Ahmed MS, Elhelaly WM, Abdisalaam S, Asaithamby A, Xing C, Kanchwala M, Vale G, Eckert KM, Mitsche MA, McDonald JG, Hill JA, Huang L, Shaul PW, Szweda LI, Sadek HA. Cardoso AC, et al. Among authors: elhelaly wm. Nat Metab. 2020 Feb;2(2):167-178. Epub 2020 Feb 20. Nat Metab. 2020. PMID: 32617517 Free PMC article.
A calcineurin-Hoxb13 axis regulates growth mode of mammalian cardiomyocytes.
Nguyen NUN, Canseco DC, Xiao F, Nakada Y, Li S, Lam NT, Muralidhar SA, Savla JJ, Hill JA, Le V, Zidan KA, El-Feky HW, Wang Z, Ahmed MS, Hubbi ME, Menendez-Montes I, Moon J, Ali SR, Le V, Villalobos E, Mohamed MS, Elhelaly WM, Thet S, Anene-Nzelu CG, Tan WLW, Foo RS, Meng X, Kanchwala M, Xing C, Roy J, Cyert MS, Rothermel BA, Sadek HA. Nguyen NUN, et al. Among authors: elhelaly wm. Nature. 2020 Jun;582(7811):271-276. doi: 10.1038/s41586-020-2228-6. Epub 2020 Apr 22. Nature. 2020. PMID: 32499640 Free PMC article.
Mechanism of Eccentric Cardiomyocyte Hypertrophy Secondary to Severe Mitral Regurgitation.
Li S, Nguyen NUN, Xiao F, Menendez-Montes I, Nakada Y, Tan WLW, Anene-Nzelu CG, Foo RS, Thet S, Cardoso AC, Wang P, Elhelaly WM, Lam NT, Pereira AHM, Hill JA, Sadek HA. Li S, et al. Among authors: elhelaly wm. Circulation. 2020 Jun 2;141(22):1787-1799. doi: 10.1161/CIRCULATIONAHA.119.043939. Epub 2020 Apr 10. Circulation. 2020. PMID: 32272846