Driscoll JJ - Search Results

1

The TGFβ type I receptor kinase inhibitor vactosertib in combination with pomalidomide in relapsed/refractory multiple myeloma: a phase 1b trial.

Malek E, Rana PS, Swamydas M, Daunov M, Miyagi M, Murphy E, Ignatz-Hoover JJ, Metheny L, Kim SJ, Driscoll JJ. Malek E, et al. Among authors: driscoll jj. Nat Commun. 2024 Aug 27;15(1):7388. doi: 10.1038/s41467-024-51442-2. Nat Commun. 2024. PMID: 39191755 Free PMC article. Clinical Trial.

2

MicroRNAs in brain metastases: potential role as diagnostics and therapeutics.

Alsidawi S, Malek E, Driscoll JJ. Alsidawi S, et al. Among authors: driscoll jj. Int J Mol Sci. 2014 Jun 11;15(6):10508-26. doi: 10.3390/ijms150610508. Int J Mol Sci. 2014. PMID: 24921708 Free PMC article. Review.

3

Correlation of long non-coding RNA expression with metastasis, drug resistance and clinical outcome in cancer.

Malek E, Jagannathan S, Driscoll JJ. Malek E, et al. Among authors: driscoll jj. Oncotarget. 2014 Sep 30;5(18):8027-38. doi: 10.18632/oncotarget.2469. Oncotarget. 2014. PMID: 25275300 Free PMC article. Review.

4

Bortezomib induces AMPK-dependent autophagosome formation uncoupled from apoptosis in drug resistant cells.

Jaganathan S, Malek E, Vallabhapurapu S, Vallabhapurapu S, Driscoll JJ. Jaganathan S, et al. Among authors: driscoll jj. Oncotarget. 2014 Dec 15;5(23):12358-70. doi: 10.18632/oncotarget.2590. Oncotarget. 2014. PMID: 25481044 Free PMC article.

5

Molecular chaperone GRP78 enhances aggresome delivery to autophagosomes to promote drug resistance in multiple myeloma.

Abdel Malek MA, Jagannathan S, Malek E, Sayed DM, Elgammal SA, Abd El-Azeem HG, Thabet NM, Driscoll JJ. Abdel Malek MA, et al. Among authors: driscoll jj. Oncotarget. 2015 Feb 20;6(5):3098-110. doi: 10.18632/oncotarget.3075. Oncotarget. 2015. PMID: 25605012 Free PMC article.

6

Pharmacologic screens reveal metformin that suppresses GRP78-dependent autophagy to enhance the anti-myeloma effect of bortezomib.

Jagannathan S, Abdel-Malek MA, Malek E, Vad N, Latif T, Anderson KC, Driscoll JJ. Jagannathan S, et al. Among authors: driscoll jj. Leukemia. 2015 Nov;29(11):2184-91. doi: 10.1038/leu.2015.157. Epub 2015 Jun 25. Leukemia. 2015. PMID: 26108695 Free PMC article.

7

Metabolic tumor volume on interim PET is a better predictor of outcome in diffuse large B-cell lymphoma than semiquantitative methods.

Malek E, Sendilnathan A, Yellu M, Petersen A, Fernandez-Ulloa M, Driscoll JJ. Malek E, et al. Among authors: driscoll jj. Blood Cancer J. 2015 Jul 24;5(7):e326. doi: 10.1038/bcj.2015.51. Blood Cancer J. 2015. PMID: 26207787 Free PMC article. No abstract available.

8

Myeloid-derived suppressor cells: The green light for myeloma immune escape.

Malek E, de Lima M, Letterio JJ, Kim BG, Finke JH, Driscoll JJ, Giralt SA. Malek E, et al. Among authors: driscoll jj. Blood Rev. 2016 Sep;30(5):341-8. doi: 10.1016/j.blre.2016.04.002. Epub 2016 Apr 12. Blood Rev. 2016. PMID: 27132116 Free PMC article. Review.

9

High throughput chemical library screening identifies a novel p110-δ inhibitor that potentiates the anti-myeloma effect of bortezomib.

Malek E, Driscoll JJ. Malek E, et al. Among authors: driscoll jj. Oncotarget. 2016 Jun 21;7(25):38523-38538. doi: 10.18632/oncotarget.9568. Oncotarget. 2016. PMID: 27229530 Free PMC article.

10

Pharmacogenomics and chemical library screens reveal a novel SCF^SKP2 inhibitor that overcomes Bortezomib resistance in multiple myeloma.

Malek E, Abdel-Malek MA, Jagannathan S, Vad N, Karns R, Jegga AG, Broyl A, van Duin M, Sonneveld P, Cottini F, Anderson KC, Driscoll JJ. Malek E, et al. Among authors: driscoll jj. Leukemia. 2017 Mar;31(3):645-653. doi: 10.1038/leu.2016.258. Epub 2016 Sep 28. Leukemia. 2017. PMID: 27677741 Free PMC article.

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