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A next-generation Fab library platform directly yielding drug-like antibodies with high affinity, diversity, and developability.
Ferrara F, Fanni A, Teixeira AAR, Molina E, Leal-Lopes C, DeAguero A, D'Angelo S, Erasmus MF, Spector L, Rodriguez Carnero LA, Li J, Pohl TJ, Suslov N, Desrumeaux K, McMahon C, Kathuria S, Bradbury ARM. Ferrara F, et al. Among authors: pohl tj. MAbs. 2024 Jan-Dec;16(1):2394230. doi: 10.1080/19420862.2024.2394230. Epub 2024 Aug 27. MAbs. 2024. PMID: 39192463 Free PMC article.
Pandemic's silver lining.
Ferrara F, D'Angelo S, Erasmus MF, Teixeira AA, Leal-Lopes C, Spector LP, Pohl T, Fanni A, Cocklin S, Bradbury ARM. Ferrara F, et al. MAbs. 2022 Jan-Dec;14(1):2133666. doi: 10.1080/19420862.2022.2133666. MAbs. 2022. PMID: 36253351 Free PMC article.
AIntibody: an experimentally validated in silico antibody discovery design challenge.
Erasmus MF, Spector L, Ferrara F, DiNiro R, Pohl TJ, Perea-Schmittle K, Wang W, Tessier PM, Richardson C, Turner L, Kumar S, Bedinger D, Sormanni P, Fernández-Quintero ML, Ward AB, Loeffler JR, Swanson OM, Deane CM, Raybould MIJ, Evers A, Sellmann C, Bachas S, Ruffolo J, Nastri HG, Ramesh K, Sørensen J, Croasdale-Wood R, Hijano O, Leal-Lopes C, Shahsavarian M, Qiu Y, Marcatili P, Vernet E, Akbar R, Friedensohn S, Wagner R, Kurella VB, Malhotra S, Kumar S, Kidger P, Almagro JC, Furfine E, Stanton M, Graff CP, Villalba SD, Tomszak F, Teixeira AAR, Hopkins E, Dovner M, D'Angelo S, Bradbury ARM. Erasmus MF, et al. Among authors: pohl tj. Nat Biotechnol. 2024 Nov;42(11):1637-1642. doi: 10.1038/s41587-024-02469-9. Nat Biotechnol. 2024. PMID: 39496931 No abstract available.
Pif1 family DNA helicases: A helpmate to RNase H?
Pohl TJ, Zakian VA. Pohl TJ, et al. DNA Repair (Amst). 2019 Dec;84:102633. doi: 10.1016/j.dnarep.2019.06.004. Epub 2019 Jun 17. DNA Repair (Amst). 2019. PMID: 31231063 Free PMC article. Review.
11 results