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Functional analysis of a common BAG3 allele associated with protection from heart failure.
Perez-Bermejo JA, Judge LM, Jensen CL, Wu K, Watry HL, Truong A, Ho JJ, Carter M, Runyon WV, Kaake RM, Pulido EH, Mandegar MA, Swaney DL, So PL, Krogan NJ, Conklin BR. Perez-Bermejo JA, et al. Among authors: mandegar ma. Nat Cardiovasc Res. 2023 Jul;2(7):615-628. doi: 10.1038/s44161-023-00288-w. Epub 2023 Jun 26. Nat Cardiovasc Res. 2023. PMID: 39195919
Automated Video-Based Analysis of Contractility and Calcium Flux in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultured over Different Spatial Scales.
Huebsch N, Loskill P, Mandegar MA, Marks NC, Sheehan AS, Ma Z, Mathur A, Nguyen TN, Yoo JC, Judge LM, Spencer CI, Chukka AC, Russell CR, So PL, Conklin BR, Healy KE. Huebsch N, et al. Among authors: mandegar ma, ma z. Tissue Eng Part C Methods. 2015 May;21(5):467-79. doi: 10.1089/ten.TEC.2014.0283. Epub 2015 Jan 14. Tissue Eng Part C Methods. 2015. PMID: 25333967 Free PMC article.
CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs.
Mandegar MA, Huebsch N, Frolov EB, Shin E, Truong A, Olvera MP, Chan AH, Miyaoka Y, Holmes K, Spencer CI, Judge LM, Gordon DE, Eskildsen TV, Villalta JE, Horlbeck MA, Gilbert LA, Krogan NJ, Sheikh SP, Weissman JS, Qi LS, So PL, Conklin BR. Mandegar MA, et al. Cell Stem Cell. 2016 Apr 7;18(4):541-53. doi: 10.1016/j.stem.2016.01.022. Epub 2016 Mar 10. Cell Stem Cell. 2016. PMID: 26971820 Free PMC article.
A BAG3 chaperone complex maintains cardiomyocyte function during proteotoxic stress.
Judge LM, Perez-Bermejo JA, Truong A, Ribeiro AJ, Yoo JC, Jensen CL, Mandegar MA, Huebsch N, Kaake RM, So PL, Srivastava D, Pruitt BL, Krogan NJ, Conklin BR. Judge LM, et al. Among authors: mandegar ma. JCI Insight. 2017 Jul 20;2(14):e94623. doi: 10.1172/jci.insight.94623. eCollection 2017 Jul 20. JCI Insight. 2017. PMID: 28724793 Free PMC article.
Phenotypic screening with deep learning identifies HDAC6 inhibitors as cardioprotective in a BAG3 mouse model of dilated cardiomyopathy.
Yang J, Grafton F, Ranjbarvaziri S, Budan A, Farshidfar F, Cho M, Xu E, Ho J, Maddah M, Loewke KE, Medina J, Sperandio D, Patel S, Hoey T, Mandegar MA. Yang J, et al. Among authors: mandegar ma. Sci Transl Med. 2022 Jul 6;14(652):eabl5654. doi: 10.1126/scitranslmed.abl5654. Epub 2022 Jul 6. Sci Transl Med. 2022. PMID: 35857625
28 results