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Rhinovirus infection of airway epithelial cells uncovers the non-ciliated subset as a likely driver of genetic risk to childhood-onset asthma.
Djeddi S, Fernandez-Salinas D, Huang GX, Aguiar VRC, Mohanty C, Kendziorski C, Gazal S, Boyce JA, Ober C, Gern JE, Barrett NA, Gutierrez-Arcelus M. Djeddi S, et al. Among authors: gern je. Cell Genom. 2024 Sep 11;4(9):100636. doi: 10.1016/j.xgen.2024.100636. Epub 2024 Aug 27. Cell Genom. 2024. PMID: 39197446 Free PMC article.
Genetic variation in immunoregulatory pathways and atopic phenotypes in infancy.
Hoffjan S, Ostrovnaja I, Nicolae D, Newman DL, Nicolae R, Gangnon R, Steiner L, Walker K, Reynolds R, Greene D, Mirel D, Gern JE, Lemanske RF Jr, Ober C. Hoffjan S, et al. Among authors: gern je. J Allergy Clin Immunol. 2004 Mar;113(3):511-8. doi: 10.1016/j.jaci.2003.10.044. J Allergy Clin Immunol. 2004. PMID: 15007355
Allele-specific targeting of microRNAs to HLA-G and risk of asthma.
Tan Z, Randall G, Fan J, Camoretti-Mercado B, Brockman-Schneider R, Pan L, Solway J, Gern JE, Lemanske RF, Nicolae D, Ober C. Tan Z, et al. Among authors: gern je. Am J Hum Genet. 2007 Oct;81(4):829-34. doi: 10.1086/521200. Epub 2007 Aug 20. Am J Hum Genet. 2007. PMID: 17847008 Free PMC article.
Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function.
Ober C, Tan Z, Sun Y, Possick JD, Pan L, Nicolae R, Radford S, Parry RR, Heinzmann A, Deichmann KA, Lester LA, Gern JE, Lemanske RF Jr, Nicolae DL, Elias JA, Chupp GL. Ober C, et al. Among authors: gern je. N Engl J Med. 2008 Apr 17;358(16):1682-91. doi: 10.1056/NEJMoa0708801. Epub 2008 Apr 9. N Engl J Med. 2008. PMID: 18403759 Free PMC article.
IFNG genotype and sex interact to influence the risk of childhood asthma.
Loisel DA, Tan Z, Tisler CJ, Evans MD, Gangnon RE, Jackson DJ, Gern JE, Lemanske RF Jr, Ober C. Loisel DA, et al. Among authors: gern je. J Allergy Clin Immunol. 2011 Sep;128(3):524-31. doi: 10.1016/j.jaci.2011.06.016. Epub 2011 Jul 27. J Allergy Clin Immunol. 2011. PMID: 21798578 Free PMC article.
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.
Torgerson DG, Ampleford EJ, Chiu GY, Gauderman WJ, Gignoux CR, Graves PE, Himes BE, Levin AM, Mathias RA, Hancock DB, Baurley JW, Eng C, Stern DA, Celedón JC, Rafaels N, Capurso D, Conti DV, Roth LA, Soto-Quiros M, Togias A, Li X, Myers RA, Romieu I, Van Den Berg DJ, Hu D, Hansel NN, Hernandez RD, Israel E, Salam MT, Galanter J, Avila PC, Avila L, Rodriquez-Santana JR, Chapela R, Rodriguez-Cintron W, Diette GB, Adkinson NF, Abel RA, Ross KD, Shi M, Faruque MU, Dunston GM, Watson HR, Mantese VJ, Ezurum SC, Liang L, Ruczinski I, Ford JG, Huntsman S, Chung KF, Vora H, Li X, Calhoun WJ, Castro M, Sienra-Monge JJ, del Rio-Navarro B, Deichmann KA, Heinzmann A, Wenzel SE, Busse WW, Gern JE, Lemanske RF Jr, Beaty TH, Bleecker ER, Raby BA, Meyers DA, London SJ; Mexico City Childhood Asthma Study (MCAAS); Gilliland FD; Children's Health Study (CHS) and HARBORS study; Burchard EG; Genetics of Asthma in Latino Americans (GALA) Study, Study of Genes-Environment and Admixture in Latino Americans (GALA2) and Study of African Americans, Asthma, Genes & Environments (SAGE); Martinez FD; Childhood Asthma Research and Education (CARE) Network; Weiss ST; Childhood Asthma Management Program… See abstract for full author list ➔ Torgerson DG, et al. Among authors: gern je. Nat Genet. 2011 Jul 31;43(9):887-92. doi: 10.1038/ng.888. Nat Genet. 2011. PMID: 21804549 Free PMC article.
Maternal microchimerism protects against the development of asthma.
Thompson EE, Myers RA, Du G, Aydelotte TM, Tisler CJ, Stern DA, Evans MD, Graves PE, Jackson DJ, Martinez FD, Gern JE, Wright AL, Lemanske RF, Ober C. Thompson EE, et al. Among authors: gern je. J Allergy Clin Immunol. 2013 Jul;132(1):39-44. doi: 10.1016/j.jaci.2012.12.1575. Epub 2013 Feb 21. J Allergy Clin Immunol. 2013. PMID: 23434286 Free PMC article.
435 results