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Convergent alterations in the tumor microenvironment of MYC-driven human and murine prostate cancer.
Graham MK, Wang R, Chikarmane R, Abel B, Vaghasia A, Gupta A, Zheng Q, Hicks J, Sysa-Shah P, Pan X, Castagna N, Liu J, Meyers J, Skaist A, Zhang Y, Rubenstein M, Schuebel K, Simons BW, Bieberich CJ, Nelson WG, Lupold SE, DeWeese TL, De Marzo AM, Yegnasubramanian S. Graham MK, et al. Nat Commun. 2024 Aug 28;15(1):7414. doi: 10.1038/s41467-024-51450-2. Nat Commun. 2024. PMID: 39198404 Free PMC article.
MYC drives overexpression of telomerase RNA (hTR/TERC) in prostate cancer.
Baena-Del Valle JA, Zheng Q, Esopi DM, Rubenstein M, Hubbard GK, Moncaliano MC, Hruszkewycz A, Vaghasia A, Yegnasubramanian S, Wheelan SJ, Meeker AK, Heaphy CM, Graham MK, De Marzo AM. Baena-Del Valle JA, et al. Among authors: graham mk. J Pathol. 2018 Jan;244(1):11-24. doi: 10.1002/path.4980. Epub 2017 Nov 14. J Pathol. 2018. PMID: 28888037 Free PMC article.
Prognostic and therapeutic potential of senescent stromal fibroblasts in prostate cancer.
Mori JO, Elhussin I, Brennen WN, Graham MK, Lotan TL, Yates CC, De Marzo AM, Denmeade SR, Yegnasubramanian S, Nelson WG, Denis GV, Platz EA, Meeker AK, Heaphy CM. Mori JO, et al. Among authors: graham mk. Nat Rev Urol. 2024 May;21(5):258-273. doi: 10.1038/s41585-023-00827-x. Epub 2023 Oct 31. Nat Rev Urol. 2024. PMID: 37907729 Review.
Functional Loss of ATRX and TERC Activates Alternative Lengthening of Telomeres (ALT) in LAPC4 Prostate Cancer Cells.
Graham MK, Kim J, Da J, Brosnan-Cashman JA, Rizzo A, Baena Del Valle JA, Chia L, Rubenstein M, Davis C, Zheng Q, Cope L, Considine M, Haffner MC, De Marzo AM, Meeker AK, Heaphy CM. Graham MK, et al. Mol Cancer Res. 2019 Dec;17(12):2480-2491. doi: 10.1158/1541-7786.MCR-19-0654. Epub 2019 Oct 14. Mol Cancer Res. 2019. PMID: 31611308 Free PMC article.
Convergent alterations in the tumor microenvironment of MYC-driven human and murine prostate cancer.
Graham MK, Wang R, Chikarmane R, Wodu B, Vaghasia A, Gupta A, Zheng Q, Hicks J, Sysa-Shah P, Pan X, Castagna N, Liu J, Meyers J, Skaist A, Zhang Y, Schuebel K, Simons BW, Bieberich CJ, Nelson WG, Lupold SE, DeWeese TL, De Marzo AM, Yegnasubramanian S. Graham MK, et al. bioRxiv [Preprint]. 2023 Oct 17:2023.09.07.553268. doi: 10.1101/2023.09.07.553268. bioRxiv. 2023. Update in: Nat Commun. 2024 Aug 28;15(1):7414. doi: 10.1038/s41467-024-51450-2 PMID: 37905029 Free PMC article. Updated. Preprint.
Pervasive promoter hypermethylation of silenced TERT alleles in human cancers.
Esopi D, Graham MK, Brosnan-Cashman JA, Meyers J, Vaghasia A, Gupta A, Kumar B, Haffner MC, Heaphy CM, De Marzo AM, Meeker AK, Nelson WG, Wheelan SJ, Yegnasubramanian S. Esopi D, et al. Among authors: graham mk. Cell Oncol (Dordr). 2020 Oct;43(5):847-861. doi: 10.1007/s13402-020-00531-7. Epub 2020 May 28. Cell Oncol (Dordr). 2020. PMID: 32468444 Free PMC article.
38 results