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ACK1 and BRK non-receptor tyrosine kinase deficiencies are associated with familial systemic lupus and involved in efferocytosis.
Guillet S, Lazarov T, Jordan N, Boisson B, Tello M, Craddock B, Zhou T, Nishi C, Bareja R, Yang H, Rieux-Laucat F, Fregel Lorenzo RI, Dyall SD, Isenberg D, D'Cruz D, Lachmann N, Elemento O, Viale A, Socci ND, Abel L, Nagata S, Huse M, Miller WT, Casanova JL, Geissmann F. Guillet S, et al. Among authors: lazarov t. Elife. 2024 Nov 21;13:RP96085. doi: 10.7554/eLife.96085. Elife. 2024. PMID: 39570652 Free PMC article.
Tuberculosis in otherwise healthy adults with inherited TNF deficiency.
Arias AA, Neehus AL, Ogishi M, Meynier V, Krebs A, Lazarov T, Lee AM, Arango-Franco CA, Yang R, Orrego J, Corcini Berndt M, Rojas J, Li H, Rinchai D, Erazo-Borrás L, Han JE, Pillay B, Ponsin K, Chaldebas M, Philippot Q, Bohlen J, Rosain J, Le Voyer T, Janotte T, Amarajeeva K, Soudée C, Brollo M, Wiegmann K, Marquant Q, Seeleuthner Y, Lee D, Lainé C, Kloos D, Bailey R, Bastard P, Keating N, Rapaport F, Khan T, Moncada-Vélez M, Carmona MC, Obando C, Alvarez J, Cataño JC, Martínez-Rosado LL, Sanchez JP, Tejada-Giraldo M, L'Honneur AS, Agudelo ML, Perez-Zapata LJ, Arboleda DM, Alzate JF, Cabarcas F, Zuluaga A, Pelham SJ, Ensser A, Schmidt M, Velásquez-Lopera MM, Jouanguy E, Puel A, Krönke M, Ghirardello S, Borghesi A, Pahari S, Boisson B, Pittaluga S, Ma CS, Emile JF, Notarangelo LD, Tangye SG, Marr N, Lachmann N, Salvator H, Schlesinger LS, Zhang P, Glickman MS, Nathan CF, Geissmann F, Abel L, Franco JL, Bustamante J, Casanova JL, Boisson-Dupuis S. Arias AA, et al. Among authors: lazarov t. Nature. 2024 Sep;633(8029):417-425. doi: 10.1038/s41586-024-07866-3. Epub 2024 Aug 28. Nature. 2024. PMID: 39198650 Free PMC article.
ACK1 and BRK non-receptor tyrosine kinase deficiencies are associated with familial systemic lupus and involved in efferocytosis.
Guillet S, Lazarov T, Jordan N, Boisson B, Tello M, Craddock B, Zhou T, Nishi C, Bareja R, Yang H, Rieux-Laucat F, Lorenzo RIF, Dyall SD, Isenberg D, D'Cruz D, Lachmann N, Elemento O, Viale A, Socci ND, Abel L, Nagata S, Huse M, Miller WT, Casanova JL, Geissmann F. Guillet S, et al. Among authors: lazarov t. medRxiv [Preprint]. 2024 Jun 5:2024.02.15.24302255. doi: 10.1101/2024.02.15.24302255. medRxiv. 2024. Update in: Elife. 2024 Nov 21;13:RP96085. doi: 10.7554/eLife.96085 PMID: 38883731 Free PMC article. Updated. Preprint.
Plasma membrane abundance dictates phagocytic capacity and functional cross-talk in myeloid cells.
Winer BY, Settle AH, Yakimov AM, Jeronimo C, Lazarov T, Tipping M, Saoi M, Sawh A, Sepp AL, Galiano M, Perry JSA, Wong YY, Geissmann F, Cross J, Zhou T, Kam LC, Pasolli HA, Hohl T, Cyster JG, Weiner OD, Huse M. Winer BY, et al. Among authors: lazarov t. Sci Immunol. 2024 Jun 7;9(96):eadl2388. doi: 10.1126/sciimmunol.adl2388. Epub 2024 Jun 7. Sci Immunol. 2024. PMID: 38848343 Free PMC article.
A microglia clonal inflammatory disorder in Alzheimer's Disease.
Vicario R, Fragkogianni S, Weber L, Lazarov T, Hu Y, Hayashi SY, Craddock BP, Socci ND, Alberdi A, Baako A, Ay O, Ogishi M, Lopez-Rodrigo E, Kappagantula R, Viale A, Iacobuzio-Donahue CA, Zhou T, Ransohoff RM, Chesworth R; Netherlands Brain Bank; Abdel-Wahab O, Boisson B, Elemento O, Casanova JL, Miller WT, Geissmann F. Vicario R, et al. Among authors: lazarov t. bioRxiv [Preprint]. 2024 Aug 3:2024.01.25.577216. doi: 10.1101/2024.01.25.577216. bioRxiv. 2024. PMID: 38328106 Free PMC article. Preprint.
The nuclear factor ID3 endows macrophages with a potent anti-tumour activity.
Deng Z, Loyher PL, Lazarov T, Li L, Shen Z, Bhinder B, Yang H, Zhong Y, Alberdi A, Massague J, Sun JC, Benezra R, Glass CK, Elemento O, Iacobuzio-Donahue CA, Geissmann F. Deng Z, et al. Among authors: lazarov t. Nature. 2024 Feb;626(8000):864-873. doi: 10.1038/s41586-023-06950-4. Epub 2024 Feb 7. Nature. 2024. PMID: 38326607 Free PMC article.
Plasma membrane abundance dictates phagocytic capacity and functional crosstalk in myeloid cells.
Winer BY, Settle AH, Yakimov AM, Jeronimo C, Lazarov T, Tipping M, Saoi M, Sawh A, Sepp AL, Galiano M, Wong YY, Perry JSA, Geissmann F, Cross J, Zhou T, Kam LC, Pasoli HA, Hohl T, Cyster JG, Weiner OD, Huse M. Winer BY, et al. Among authors: lazarov t. bioRxiv [Preprint]. 2023 Sep 13:2023.09.12.556572. doi: 10.1101/2023.09.12.556572. bioRxiv. 2023. Update in: Sci Immunol. 2024 Jun 7;9(96):eadl2388. doi: 10.1126/sciimmunol.adl2388 PMID: 37745515 Free PMC article. Updated. Preprint.
Early life high fructose exposure disrupts microglia function and impedes neurodevelopment.
Wang Z, Lipshutz A, Liu ZL, Trzeciak AJ, Miranda IC, Martínez de la Torre C, Schild T, Lazarov T, Rojas WS, Saavedra PHV, Romero-Pichardo JE, Baako A, Geissmann F, Faraco G, Gan L, Etchegaray JI, Lucas CD, Parkhurst CN, Zeng MY, Keshari KR, Perry JSA. Wang Z, et al. Among authors: lazarov t. bioRxiv [Preprint]. 2023 Aug 15:2023.08.14.553242. doi: 10.1101/2023.08.14.553242. bioRxiv. 2023. PMID: 37645894 Free PMC article. Preprint.
Physiology and diseases of tissue-resident macrophages.
Lazarov T, Juarez-Carreño S, Cox N, Geissmann F. Lazarov T, et al. Nature. 2023 Jun;618(7966):698-707. doi: 10.1038/s41586-023-06002-x. Epub 2023 Jun 21. Nature. 2023. PMID: 37344646 Free PMC article. Review.
25 results