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AAV-NDI1 Therapy Provides Significant Benefit to Murine and Cellular Models of Glaucoma.
Millington-Ward S, Palfi A, Shortall C, Finnegan LK, Bargroff E, Post IJM, Maguire J, Irnaten M, O Brien C, Kenna PF, Chadderton N, Farrar GJ. Millington-Ward S, et al. Among authors: chadderton n. Int J Mol Sci. 2024 Aug 15;25(16):8876. doi: 10.3390/ijms25168876. Int J Mol Sci. 2024. PMID: 39201561 Free PMC article.
Novel 199 base pair NEFH promoter drives expression in retinal ganglion cells.
Millington-Ward S, Chadderton N, Berkeley M, Finnegan LK, Hanlon KS, Carrigan M, Humphries P, Kenna PF, Palfi A, Farrar GJ. Millington-Ward S, et al. Among authors: chadderton n. Sci Rep. 2020 Oct 5;10(1):16515. doi: 10.1038/s41598-020-73257-z. Sci Rep. 2020. PMID: 33020509 Free PMC article.
AAV-mediated gene therapy improving mitochondrial function provides benefit in age-related macular degeneration models.
Millington-Ward S, Chadderton N, Finnegan LK, Post IJM, Carrigan M, Gardiner T, Peixoto E, Maloney D, Humphries MM, Stitt A, Léveillard T, Humphries P, Kenna PF, Palfi A, Farrar GJ. Millington-Ward S, et al. Among authors: chadderton n. Clin Transl Med. 2022 Aug;12(8):e952. doi: 10.1002/ctm2.952. Clin Transl Med. 2022. PMID: 35988157 Free PMC article. No abstract available.
RPE-Directed Gene Therapy Improves Mitochondrial Function in Murine Dry AMD Models.
Millington-Ward S, Chadderton N, Finnegan LK, Post IJM, Carrigan M, Nixon R, Humphries MM, Humphries P, Kenna PF, Palfi A, Farrar GJ. Millington-Ward S, et al. Among authors: chadderton n. Int J Mol Sci. 2023 Feb 14;24(4):3847. doi: 10.3390/ijms24043847. Int J Mol Sci. 2023. PMID: 36835257 Free PMC article.
RNA interference-mediated suppression and replacement of human rhodopsin in vivo.
O'Reilly M, Palfi A, Chadderton N, Millington-Ward S, Ader M, Cronin T, Tuohy T, Auricchio A, Hildinger M, Tivnan A, McNally N, Humphries MM, Kiang AS, Humphries P, Kenna PF, Farrar GJ. O'Reilly M, et al. Among authors: chadderton n. Am J Hum Genet. 2007 Jul;81(1):127-35. doi: 10.1086/519025. Epub 2007 May 23. Am J Hum Genet. 2007. PMID: 17564969 Free PMC article.
35 results