Shearer J - Search Results

1

Preclinical Safety Assessment of the EBS-LASV Vaccine Candidate against Lassa Fever Virus.

Matassov D, DeWald LE, Hamm S, Nowak RM, Gerardi CS, Latham TE, Xu R, Luckay A, Chen T, Tremblay M, Shearer J, Wynn M, Eldridge JH, Warfield K, Spurgers K. Matassov D, et al. Among authors: shearer j. Vaccines (Basel). 2024 Jul 30;12(8):858. doi: 10.3390/vaccines12080858. Vaccines (Basel). 2024. PMID: 39203984 Free PMC article.

2

Investigational New Drug Enabling Nonclinical Safety Assessment of the Iminosugar UV-4, a Broad-Spectrum Host-Targeted Antiviral Agent.

Shearer J, Wolfe G, Sampath A, Warfield KL, Kaufman B, Ramstedt U, Treston A. Shearer J, et al. Int J Toxicol. 2022 May-Jun;41(3):182-200. doi: 10.1177/10915818221077225. Epub 2022 Apr 15. Int J Toxicol. 2022. PMID: 35426748

3

Investigational New Drug Enabling Nonclinical Safety Pharmacology Assessment of the Iminosugar UV-4, a Broad-Spectrum Host-Targeted Antiviral Agent.

Shearer J, Wolfe G, Sampath A, Warfield KL, Kaufman B, Ramstedt U, Treston A. Shearer J, et al. Int J Toxicol. 2022 May-Jun;41(3):201-211. doi: 10.1177/10915818211072842. Epub 2022 Feb 28. Int J Toxicol. 2022. PMID: 35227115 Free PMC article.

4

Reproductive and developmental toxicology studies of iminosugar UV-4.

Shearer J, Wolfe G, Khaliq M, Kaufman B, Sampath A, Warfield KL, Ramstedt U, Treston A. Shearer J, et al. Reprod Toxicol. 2022 Dec;114:9-21. doi: 10.1016/j.reprotox.2022.09.007. Epub 2022 Oct 4. Reprod Toxicol. 2022. PMID: 36206921 Free article.

5

GC-072: A Novel Therapeutic Candidate for Oral Treatment of Melioidosis and Infections Caused by Select Biothreat Pathogens.

Shearer JD, Saylor ML, Butler CM, Treston AM, Heine HS, Chirakul S, Schweizer HP, Louie A, Drusano GL, Zumbrun SD, Warfield KL. Shearer JD, et al. Antimicrob Agents Chemother. 2019 Sep 9;63(12):e00834-19. doi: 10.1128/AAC.00834-19. Epub 2019 Sep 23. Antimicrob Agents Chemother. 2019. PMID: 31548183 Free PMC article.

6

Developmental and reproductive safety evaluation of AV7909 anthrax vaccine candidate in rats.

Mylchreest E, Smiley MA, Ballin JD, Blauth B, Shearer J, Reece J, Ionin B, Savransky V. Mylchreest E, et al. Among authors: shearer j. Birth Defects Res. 2021 Jan 1;113(1):32-42. doi: 10.1002/bdr2.1815. Epub 2020 Oct 16. Birth Defects Res. 2021. PMID: 33067910 Free PMC article.

7

Repeat Dose Toxicity Study of the AV7909 Anthrax Vaccine Candidate in Juvenile Rats.

Zmarowski A, Ballin JD, Sharits J, Carrico K, Novak J, Shearer J, Blauth B, Ionin B, Reece J, Savransky V. Zmarowski A, et al. Among authors: shearer j. Int J Toxicol. 2020 Jul 21:1091581820941412. doi: 10.1177/1091581820941412. Online ahead of print. Int J Toxicol. 2020. PMID: 32691648

8

Repeat-Dose Toxicity Study of a Lyophilized Recombinant Protective Antigen-Based Anthrax Vaccine Adjuvanted With CpG 7909.

Savransky V, Lacy M, Ionin B, Skiadopoulos MH, Shearer J. Savransky V, et al. Among authors: shearer j. Int J Toxicol. 2019 May/Jun;38(3):163-172. doi: 10.1177/1091581819848722. Int J Toxicol. 2019. PMID: 31179828

9

Efficacy of the AV7909 anthrax vaccine candidate in guinea pigs and nonhuman primates following two immunizations two weeks apart.

Shearer JD, Henning L, Sanford DC, Li N, Skiadopoulos MH, Reece JJ, Ionin B, Savransky V. Shearer JD, et al. Vaccine. 2021 Jan 3;39(1):1-5. doi: 10.1016/j.vaccine.2020.10.095. Epub 2020 Nov 13. Vaccine. 2021. PMID: 33199078 Free article.

10

Preclinical safety assessment of a recombinant plague vaccine (rF1V).

Price JL, Manetz TS, Shearer JD, House RV. Price JL, et al. Int J Toxicol. 2013 Sep-Oct;32(5):327-35. doi: 10.1177/1091581813497405. Epub 2013 Aug 1. Int J Toxicol. 2013. PMID: 23908395

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