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A targetable type III immune response with increase of IL-17A expressing CD4+ T cells is associated with immunotherapy-induced toxicity in melanoma.
Dimitriou F, Cheng PF, Saltari A, Schaper-Gerhardt K, Staeger R, Haunerdinger V, Sella F, Tastanova A, Urban C, Dettwiler S, Mihic-Probst D, Matter CM, Michielin O, Gutzmer R, Long GV, Becher B, Levesque MP, Dummer R. Dimitriou F, et al. Among authors: becher b. Nat Cancer. 2024 Sep;5(9):1390-1408. doi: 10.1038/s43018-024-00810-4. Epub 2024 Aug 29. Nat Cancer. 2024. PMID: 39210005 Free PMC article.
SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis.
Stein S, Lohmann C, Schäfer N, Hofmann J, Rohrer L, Besler C, Rothgiesser KM, Becher B, Hottiger MO, Borén J, McBurney MW, Landmesser U, Lüscher TF, Matter CM. Stein S, et al. Among authors: becher b. Eur Heart J. 2010 Sep;31(18):2301-9. doi: 10.1093/eurheartj/ehq107. Epub 2010 Apr 23. Eur Heart J. 2010. PMID: 20418343 Free PMC article.
Regulatory T Cells Restrain Pathogenic T Helper Cells during Skin Inflammation.
Hartwig T, Zwicky P, Schreiner B, Yawalkar N, Cheng P, Navarini A, Dummer R, Flatz L, Conrad C, Schlapbach C, Becher B. Hartwig T, et al. Among authors: becher b. Cell Rep. 2018 Dec 26;25(13):3564-3572.e4. doi: 10.1016/j.celrep.2018.12.012. Cell Rep. 2018. PMID: 30590032 Free article.
MDM2 Inhibition Enhances Immune Checkpoint Inhibitor Efficacy by Increasing IL15 and MHC Class II Production.
Langenbach M, Giesler S, Richtsfeld S, Costa-Pereira S, Rindlisbacher L, Wertheimer T, Braun LM, Andrieux G, Duquesne S, Pfeifer D, Woessner NM, Menssen HD, Taromi S, Duyster J, Börries M, Brummer T, Blazar BR, Minguet S, Turko P, Levesque MP, Becher B, Zeiser R. Langenbach M, et al. Among authors: becher b. Mol Cancer Res. 2023 Aug 1;21(8):849-864. doi: 10.1158/1541-7786.MCR-22-0898. Mol Cancer Res. 2023. PMID: 37071397 Free PMC article.
Requirement of JNK2 for scavenger receptor A-mediated foam cell formation in atherogenesis.
Ricci R, Sumara G, Sumara I, Rozenberg I, Kurrer M, Akhmedov A, Hersberger M, Eriksson U, Eberli FR, Becher B, Borén J, Chen M, Cybulsky MI, Moore KJ, Freeman MW, Wagner EF, Matter CM, Lüscher TF. Ricci R, et al. Among authors: becher b. Science. 2004 Nov 26;306(5701):1558-61. doi: 10.1126/science.1101909. Science. 2004. PMID: 15567863
315 results