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Inflammatory lung injury is associated with endothelial cell mitochondrial fission and requires the nitration of RhoA and cytoskeletal remodeling.
Pokharel MD, Fu P, Garcia-Flores A, Yegambaram M, Lu Q, Sun X, Unwalla H, Aggarwal S, Fineman JR, Wang T, Black SM. Pokharel MD, et al. Among authors: wang t. Free Radic Biol Med. 2024 Aug 20;221:125-135. doi: 10.1016/j.freeradbiomed.2024.05.019. Epub 2024 May 10. Free Radic Biol Med. 2024. PMID: 38734269 Free article.
Mitochondrial hyperfusion induces metabolic remodeling in lung endothelial cells by modifying the activities of electron transport chain complexes I and III.
Yegambaram M, Sun X, Lu Q, Jin Y, Ornatowski W, Soto J, Aggarwal S, Wang T, Tieu K, Gu H, Fineman JR, Black SM. Yegambaram M, et al. Among authors: wang t. Free Radic Biol Med. 2024 Jan;210:183-194. doi: 10.1016/j.freeradbiomed.2023.11.008. Epub 2023 Nov 17. Free Radic Biol Med. 2024. PMID: 37979892
Metabolic reprogramming, oxidative stress, and pulmonary hypertension.
Pokharel MD, Marciano DP, Fu P, Franco MC, Unwalla H, Tieu K, Fineman JR, Wang T, Black SM. Pokharel MD, et al. Among authors: wang t. Redox Biol. 2023 Aug;64:102797. doi: 10.1016/j.redox.2023.102797. Epub 2023 Jun 24. Redox Biol. 2023. PMID: 37392518 Free PMC article. Review.
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