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Page 1
Tumor-agnostic cancer therapy using antibodies targeting oncofetal chondroitin sulfate.
Vidal-Calvo EE, Martin-Salazar A, Choudhary S, Dagil R, Raghavan SSR, Duvnjak L, Nordmaj MA, Clausen TM, Skafte A, Oberkofler J, Wang K, Agerbæk MØ, Løppke C, Jørgensen AM, Ropac D, Mujollari J, Willis S, Garcias López A, Miller RL, Karlsson RTG, Goerdeler F, Chen YH, Colaço AR, Wang Y, Lavstsen T, Martowicz A, Nelepcu I, Marzban M, Oo HZ, Ørum-Madsen MS, Wang Y, Nielsen MA, Clausen H, Wierer M, Wolf D, Gögenur I, Theander TG, Al-Nakouzi N, Gustavsson T, Daugaard M, Salanti A. Vidal-Calvo EE, et al. Among authors: orum madsen ms. Nat Commun. 2024 Aug 30;15(1):7553. doi: 10.1038/s41467-024-51781-0. Nat Commun. 2024. PMID: 39215044 Free PMC article.
Malaria Biomimetic for Tumor Targeted Drug Delivery.
Pihl J, Clausen TM, Zhou J, Krishnan N, Ørum-Madsen MS, Gustavsson T, Dagil R, Daugaard M, Choudhary S, Foged C, Esko JD, Zhang L, Fang RH, Salanti A. Pihl J, et al. Among authors: orum madsen ms. ACS Nano. 2023 Jul 25;17(14):13500-13509. doi: 10.1021/acsnano.3c01910. Epub 2023 Jul 12. ACS Nano. 2023. PMID: 37435892
Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma.
Zhang HF, Hughes CS, Li W, He JZ, Surdez D, El-Naggar AM, Cheng H, Prudova A, Delaidelli A, Negri GL, Li X, Ørum-Madsen MS, Lizardo MM, Oo HZ, Colborne S, Shyp T, Scopim-Ribeiro R, Hammond CA, Dhez AC, Langman S, Lim JKM, Kung SHY, Li A, Steino A, Daugaard M, Parker SJ, Geltink RIK, Orentas RJ, Xu LY, Morin GB, Delattre O, Dimitrov DS, Sorensen PH. Zhang HF, et al. Among authors: orum madsen ms. Cancer Discov. 2021 Nov;11(11):2884-2903. doi: 10.1158/2159-8290.CD-20-1690. Epub 2021 May 21. Cancer Discov. 2021. PMID: 34021002 Free PMC article.
Development of a bispecific immune engager using a recombinant malaria protein.
Nordmaj MA, Roberts ME, Sachse ES, Dagil R, Andersen AP, Skeltved N, Grunddal KV, Erdoğan SM, Choudhary S, Gustsavsson T, Ørum-Madsen MS, Moskalev I, Tian W, Yang Z, Clausen TM, Theander TG, Daugaard M, Nielsen MA, Salanti A. Nordmaj MA, et al. Among authors: orum madsen ms. Cell Death Dis. 2021 Apr 6;12(4):353. doi: 10.1038/s41419-021-03611-0. Cell Death Dis. 2021. PMID: 33824272 Free PMC article.
A simple method for detecting oncofetal chondroitin sulfate glycosaminoglycans in bladder cancer urine.
Clausen TM, Kumar G, Ibsen EK, Ørum-Madsen MS, Hurtado-Coll A, Gustavsson T, Agerbæk MØ, Gatto F, Todenhöfer T, Basso U, Knowles MA, Sanchez-Carbayo M, Salanti A, Black PC, Daugaard M. Clausen TM, et al. Among authors: orum madsen ms. Cell Death Discov. 2020 Jul 27;6:65. doi: 10.1038/s41420-020-00304-z. eCollection 2020. Cell Death Discov. 2020. PMID: 32793395 Free PMC article.
An Oncofetal Glycosaminoglycan Modification Provides Therapeutic Access to Cisplatin-resistant Bladder Cancer.
Seiler R, Oo HZ, Tortora D, Clausen TM, Wang CK, Kumar G, Pereira MA, Ørum-Madsen MS, Agerbæk MØ, Gustavsson T, Nordmaj MA, Rich JR, Lallous N, Fazli L, Lee SS, Douglas J, Todenhöfer T, Esfandnia S, Battsogt D, Babcook JS, Al-Nakouzi N, Crabb SJ, Moskalev I, Kiss B, Davicioni E, Thalmann GN, Rennie PS, Black PC, Salanti A, Daugaard M. Seiler R, et al. Among authors: orum madsen ms. Eur Urol. 2017 Jul;72(1):142-150. doi: 10.1016/j.eururo.2017.03.021. Epub 2017 Apr 10. Eur Urol. 2017. PMID: 28408175
Oncofetal Chondroitin Sulfate Glycosaminoglycans Are Key Players in Integrin Signaling and Tumor Cell Motility.
Clausen TM, Pereira MA, Al Nakouzi N, Oo HZ, Agerbæk MØ, Lee S, Ørum-Madsen MS, Kristensen AR, El-Naggar A, Grandgenett PM, Grem JL, Hollingsworth MA, Holst PJ, Theander T, Sorensen PH, Daugaard M, Salanti A. Clausen TM, et al. Among authors: orum madsen ms. Mol Cancer Res. 2016 Dec;14(12):1288-1299. doi: 10.1158/1541-7786.MCR-16-0103. Epub 2016 Sep 21. Mol Cancer Res. 2016. PMID: 27655130 Free PMC article.
TIMP-1 is under regulation of the EGF signaling axis and promotes an aggressive phenotype in KRAS-mutated colorectal cancer cells: a potential novel approach to the treatment of metastatic colorectal cancer.
Tarpgaard LS, Ørum-Madsen MS, Christensen IJ, Nordgaard C, Noer J, Guren TK, Glimelius B, Sorbye H, Ikdahl T, Kure EH, Tveit KM, Nielsen HJ, Pfeiffer P, Brünner N, Moreira JM. Tarpgaard LS, et al. Among authors: orum madsen ms. Oncotarget. 2016 Sep 13;7(37):59441-59457. doi: 10.18632/oncotarget.11118. Oncotarget. 2016. PMID: 27509063 Free PMC article. Clinical Trial.