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Tumor-agnostic cancer therapy using antibodies targeting oncofetal chondroitin sulfate.
Vidal-Calvo EE, Martin-Salazar A, Choudhary S, Dagil R, Raghavan SSR, Duvnjak L, Nordmaj MA, Clausen TM, Skafte A, Oberkofler J, Wang K, Agerbæk MØ, Løppke C, Jørgensen AM, Ropac D, Mujollari J, Willis S, Garcias López A, Miller RL, Karlsson RTG, Goerdeler F, Chen YH, Colaço AR, Wang Y, Lavstsen T, Martowicz A, Nelepcu I, Marzban M, Oo HZ, Ørum-Madsen MS, Wang Y, Nielsen MA, Clausen H, Wierer M, Wolf D, Gögenur I, Theander TG, Al-Nakouzi N, Gustavsson T, Daugaard M, Salanti A. Vidal-Calvo EE, et al. Among authors: wang k, wang y. Nat Commun. 2024 Aug 30;15(1):7553. doi: 10.1038/s41467-024-51781-0. Nat Commun. 2024. PMID: 39215044 Free PMC article.
Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding.
Wang K, Dagil R, Lavstsen T, Misra SK, Spliid CB, Wang Y, Gustavsson T, Sandoval DR, Vidal-Calvo EE, Choudhary S, Agerbaek MØ, Lindorff-Larsen K, Nielsen MA, Theander TG, Sharp JS, Clausen TM, Gourdon P, Salanti A. Wang K, et al. Among authors: wang y. Nat Commun. 2021 May 19;12(1):2956. doi: 10.1038/s41467-021-23254-1. Nat Commun. 2021. PMID: 34011972 Free PMC article.
Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA.
Raghavan SSR, Dagil R, Lopez-Perez M, Conrad J, Bassi MR, Quintana MDP, Choudhary S, Gustavsson T, Wang Y, Gourdon P, Ofori MF, Christensen SB, Minja DTR, Schmiegelow C, Nielsen MA, Barfod L, Hviid L, Salanti A, Lavstsen T, Wang K. Raghavan SSR, et al. Among authors: wang k, wang y. PLoS Pathog. 2022 Nov 16;18(11):e1010924. doi: 10.1371/journal.ppat.1010924. eCollection 2022 Nov. PLoS Pathog. 2022. PMID: 36383559 Free PMC article.
Structure and transport mechanism of P5B-ATPases.
Li P, Wang K, Salustros N, Grønberg C, Gourdon P. Li P, et al. Among authors: wang k. Nat Commun. 2021 Jun 25;12(1):3973. doi: 10.1038/s41467-021-24148-y. Nat Commun. 2021. PMID: 34172751 Free PMC article.
Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function.
Zhang L, Simonsen C, Zimova L, Wang K, Moparthi L, Gaudet R, Ekoff M, Nilsson G, Hellmich UA, Vlachova V, Gourdon P, Zygmunt PM. Zhang L, et al. Among authors: wang k. Nat Commun. 2022 Dec 5;13(1):7483. doi: 10.1038/s41467-022-35163-y. Nat Commun. 2022. PMID: 36470868 Free PMC article.
The structure and function of P5A-ATPases.
Li P, Bågenholm V, Hägglund P, Lindkvist-Petersson K, Wang K, Gourdon P. Li P, et al. Among authors: wang k. Nat Commun. 2024 Nov 6;15(1):9605. doi: 10.1038/s41467-024-53757-6. Nat Commun. 2024. PMID: 39505844 Free PMC article.
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