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Page 1
A common druggable signature of oncogenic c-Myc, mutant KRAS and mutant p53 reveals functional redundancy and competition among oncogenes in cancer.
Grześ M, Jaiswar A, Grochowski M, Wojtyś W, Kaźmierczak W, Olesiński T, Lenarcik M, Nowak-Niezgoda M, Kołos M, Canarutto G, Piazza S, Wiśniewski JR, Walerych D. Grześ M, et al. Among authors: canarutto g. Cell Death Dis. 2024 Aug 31;15(8):638. doi: 10.1038/s41419-024-06965-3. Cell Death Dis. 2024. PMID: 39217152 Free PMC article.
NFKBIE mutations are selected by the tumor microenvironment and contribute to immune escape in chronic lymphocytic leukemia.
Bonato A, Chakraborty S, Bomben R, Canarutto G, Felician G, Martines C, Zucchetto A, Pozzo F, Vujovikj M, Polesel J, Chiarenza A, Del Principe MI, Del Poeta G, D'Arena G, Marasca R, Tafuri A, Laurenti L, Piazza S, Dimovski AJ, Gattei V, Efremov DG. Bonato A, et al. Among authors: canarutto g. Leukemia. 2024 Jul;38(7):1511-1521. doi: 10.1038/s41375-024-02224-8. Epub 2024 Mar 15. Leukemia. 2024. PMID: 38486128 Free PMC article.
CRISPR-Cas9-mediated somatic correction of a one-base deletion in the Ugt1a gene ameliorates hyperbilirubinemia in Crigler-Najjar syndrome mice.
Bortolussi G, Iaconcig A, Canarutto G, Porro F, Ferrucci F, Galletta C, Díaz-Muñoz C, Rawat V, De Caneva A, Olajide OJ, Zentilin L, Piazza S, Bočkor L, Muro AF. Bortolussi G, et al. Among authors: canarutto g. Mol Ther Methods Clin Dev. 2023 Nov 19;31:101161. doi: 10.1016/j.omtm.2023.101161. eCollection 2023 Dec 14. Mol Ther Methods Clin Dev. 2023. PMID: 38094199 Free PMC article.
HuR modulation counteracts lipopolysaccharide response in murine macrophages.
Bonomo I, Assoni G, La Pietra V, Canarutto G, Facen E, Donati G, Zucal C, Genovese S, Micaelli M, Pérez-Ràfols A, Robbiati S, Kontoyannis DL, De Matteo M, Fragai M, Seneci P, Marinelli L, Arosio D, Piazza S, Provenzani A. Bonomo I, et al. Among authors: canarutto g. Dis Model Mech. 2023 Mar 1;16(3):dmm050120. doi: 10.1242/dmm.050120. Epub 2023 Mar 29. Dis Model Mech. 2023. PMID: 36912171 Free PMC article.
CXCL5-mediated accumulation of mature neutrophils in lung cancer tissues impairs the differentiation program of anticancer CD8 T cells and limits the efficacy of checkpoint inhibitors.
Simoncello F, Piperno GM, Caronni N, Amadio R, Cappelletto A, Canarutto G, Piazza S, Bicciato S, Benvenuti F. Simoncello F, et al. Among authors: canarutto g. Oncoimmunology. 2022 Apr 7;11(1):2059876. doi: 10.1080/2162402X.2022.2059876. eCollection 2022. Oncoimmunology. 2022. PMID: 35402081 Free PMC article.