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A common druggable signature of oncogenic c-Myc, mutant KRAS and mutant p53 reveals functional redundancy and competition among oncogenes in cancer.
Grześ M, Jaiswar A, Grochowski M, Wojtyś W, Kaźmierczak W, Olesiński T, Lenarcik M, Nowak-Niezgoda M, Kołos M, Canarutto G, Piazza S, Wiśniewski JR, Walerych D. Grześ M, et al. Among authors: piazza s. Cell Death Dis. 2024 Aug 31;15(8):638. doi: 10.1038/s41419-024-06965-3. Cell Death Dis. 2024. PMID: 39217152 Free PMC article.
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer.
Walerych D, Lisek K, Sommaggio R, Piazza S, Ciani Y, Dalla E, Rajkowska K, Gaweda-Walerych K, Ingallina E, Tonelli C, Morelli MJ, Amato A, Eterno V, Zambelli A, Rosato A, Amati B, Wiśniewski JR, Del Sal G. Walerych D, et al. Among authors: piazza s. Nat Cell Biol. 2016 Aug;18(8):897-909. doi: 10.1038/ncb3380. Epub 2016 Jun 27. Nat Cell Biol. 2016. PMID: 27347849 Free article.
Mutant p53 induces Golgi tubulo-vesiculation driving a prometastatic secretome.
Capaci V, Bascetta L, Fantuz M, Beznoussenko GV, Sommaggio R, Cancila V, Bisso A, Campaner E, Mironov AA, Wiśniewski JR, Ulloa Severino L, Scaini D, Bossi F, Lees J, Alon N, Brunga L, Malkin D, Piazza S, Collavin L, Rosato A, Bicciato S, Tripodo C, Mantovani F, Del Sal G. Capaci V, et al. Among authors: piazza s. Nat Commun. 2020 Aug 7;11(1):3945. doi: 10.1038/s41467-020-17596-5. Nat Commun. 2020. PMID: 32770028 Free PMC article.
Translating Proteomic Into Functional Data: An High Mobility Group A1 (HMGA1) Proteomic Signature Has Prognostic Value in Breast Cancer.
Maurizio E, Wiśniewski JR, Ciani Y, Amato A, Arnoldo L, Penzo C, Pegoraro S, Giancotti V, Zambelli A, Piazza S, Manfioletti G, Sgarra R. Maurizio E, et al. Among authors: piazza s. Mol Cell Proteomics. 2016 Jan;15(1):109-23. doi: 10.1074/mcp.M115.050401. Epub 2015 Nov 2. Mol Cell Proteomics. 2016. PMID: 26527623 Free PMC article.
CXCL5-mediated accumulation of mature neutrophils in lung cancer tissues impairs the differentiation program of anticancer CD8 T cells and limits the efficacy of checkpoint inhibitors.
Simoncello F, Piperno GM, Caronni N, Amadio R, Cappelletto A, Canarutto G, Piazza S, Bicciato S, Benvenuti F. Simoncello F, et al. Among authors: piazza s. Oncoimmunology. 2022 Apr 7;11(1):2059876. doi: 10.1080/2162402X.2022.2059876. eCollection 2022. Oncoimmunology. 2022. PMID: 35402081 Free PMC article.
A Pin1/mutant p53 axis promotes aggressiveness in breast cancer.
Girardini JE, Napoli M, Piazza S, Rustighi A, Marotta C, Radaelli E, Capaci V, Jordan L, Quinlan P, Thompson A, Mano M, Rosato A, Crook T, Scanziani E, Means AR, Lozano G, Schneider C, Del Sal G. Girardini JE, et al. Among authors: piazza s. Cancer Cell. 2011 Jul 12;20(1):79-91. doi: 10.1016/j.ccr.2011.06.004. Cancer Cell. 2011. PMID: 21741598 Free article.
370 results