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Protospacer modification improves base editing of a canonical splice site variant and recovery of CFTR function in human airway epithelial cells.
Joynt AT, Kavanagh EW, Newby GA, Mitchell S, Eastman AC, Paul KC, Bowling AD, Osorio DL, Merlo CA, Patel SU, Raraigh KS, Liu DR, Sharma N, Cutting GR. Joynt AT, et al. Among authors: sharma n. Mol Ther Nucleic Acids. 2023 Jun 29;33:335-350. doi: 10.1016/j.omtn.2023.06.020. eCollection 2023 Sep 12. Mol Ther Nucleic Acids. 2023. PMID: 37547293 Free PMC article.
Genetics of Cystic Fibrosis: Clinical Implications.
Joynt AT, Cutting GR, Sharma N. Joynt AT, et al. Among authors: sharma n. Clin Chest Med. 2022 Dec;43(4):591-602. doi: 10.1016/j.ccm.2022.06.003. Clin Chest Med. 2022. PMID: 36344068 Review.
Use of adenine base editing and homology-independent targeted integration strategies to correct the cystic fibrosis causing variant, W1282X.
Mention K, Cavusoglu-Doran K, Joynt AT, Santos L, Sanz D, Eastman AC, Merlo C, Langfelder-Schwind E, Scallan MF, Farinha CM, Cutting GR, Sharma N, Harrison PT. Mention K, et al. Among authors: sharma n. Hum Mol Genet. 2023 Nov 17;32(23):3237-3248. doi: 10.1093/hmg/ddad143. Hum Mol Genet. 2023. PMID: 37649273 Free PMC article.
Investigation of CFTR Function in Human Nasal Epithelial Cells Informs Personalized Medicine.
Pion A, Kavanagh E, Joynt AT, Raraigh KS, Vanscoy L, Langfelder-Schwind E, McNamara J, Moore B, Patel S, Merlo K, Temme R, Capurro V, Pesce E, Merlo C, Pedemonte N, Cutting GR, Sharma N. Pion A, et al. Among authors: sharma n. Am J Respir Cell Mol Biol. 2024 Nov;71(5):577-588. doi: 10.1165/rcmb.2023-0398OC. Am J Respir Cell Mol Biol. 2024. PMID: 39012815
Machine Learning-Guided Fluid Resuscitation for Acute Pancreatitis Improves Outcomes.
Kong N, Chang P, Ira S, Haq U, Amini M, Nguyen D, Khan F, Narala R, Sharma N, Wang D, Thompson T, Sadik J, Breze C, Whitcomb DC, Buxbaum JL. Kong N, et al. Among authors: sharma n. Clin Transl Gastroenterol. 2025 Jan 24. doi: 10.14309/ctg.0000000000000825. Online ahead of print. Clin Transl Gastroenterol. 2025. PMID: 39851257
7,442 results