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Harnessing cellular therapeutics for type 1 diabetes mellitus: progress, challenges, and the road ahead.
Grattoni A, Korbutt G, Tomei AA, García AJ, Pepper AR, Stabler C, Brehm M, Papas K, Citro A, Shirwan H, Millman JR, Melero-Martin J, Graham M, Sefton M, Ma M, Kenyon N, Veiseh O, Desai TA, Nostro MC, Marinac M, Sykes M, Russ HA, Odorico J, Tang Q, Ricordi C, Latres E, Mamrak NE, Giraldo J, Poznansky MC, de Vos P. Grattoni A, et al. Among authors: papas k. Nat Rev Endocrinol. 2025 Jan;21(1):14-30. doi: 10.1038/s41574-024-01029-0. Epub 2024 Sep 3. Nat Rev Endocrinol. 2025. PMID: 39227741 Review.
Preliminary Studies of the Impact of CXCL12 on the Foreign Body Reaction to Pancreatic Islets Microencapsulated in Alginate in Nonhuman Primates.
Sremac M, Lei J, Penson MFE, Schuetz C, Lakey JRT, Papas KK, Varde PS, Hering B, de Vos P, Brauns T, Markmann J, Poznansky MC. Sremac M, et al. Among authors: papas kk. Transplant Direct. 2019 Apr 15;5(5):e447. doi: 10.1097/TXD.0000000000000890. eCollection 2019 May. Transplant Direct. 2019. PMID: 31165082 Free PMC article.
Long-term Outcomes With Islet-Alone and Islet-After-Kidney Transplantation for Type 1 Diabetes in the Clinical Islet Transplantation Consortium: The CIT-08 Study.
Rickels MR, Eggerman TL, Bayman L, Qidwai JC, Alejandro R, Bridges ND, Hering BJ, Markmann JF, Senior PA, Hunsicker LG; Clinical Islet Transplantation Consortium. Rickels MR, et al. Diabetes Care. 2022 Oct 17;45(12):2967-75. doi: 10.2337/dc21-2688. Online ahead of print. Diabetes Care. 2022. PMID: 36250905 Free PMC article.
In vitro characterization of neonatal, juvenile, and adult porcine islet oxygen demand, β-cell function, and transcriptomes.
Smith KE, Purvis WG, Davis MA, Min CG, Cooksey AM, Weber CS, Jandova J, Price ND, Molano DS, Stanton JB, Kelly AC, Steyn LV, Lynch RM, Limesand SW, Alexander M, Lakey JRT, Seeberger K, Korbutt GS, Mueller KR, Hering BJ, McCarthy FM, Papas KK. Smith KE, et al. Among authors: papas kk. Xenotransplantation. 2018 Nov;25(6):e12432. doi: 10.1111/xen.12432. Epub 2018 Jul 27. Xenotransplantation. 2018. PMID: 30052287
An inverse-breathing encapsulation system for cell delivery.
Wang LH, Ernst AU, Flanders JA, Liu W, Wang X, Datta AK, Epel B, Kotecha M, Papas KK, Ma M. Wang LH, et al. Among authors: papas kk. Sci Adv. 2021 May 14;7(20):eabd5835. doi: 10.1126/sciadv.abd5835. Print 2021 May. Sci Adv. 2021. PMID: 33990318 Free PMC article.
Hypoxia within subcutaneously implanted macroencapsulation devices limits the viability and functionality of densely loaded islets.
Einstein SA, Steyn LV, Weegman BP, Suszynski TM, Sambanis A, O'Brien TD, Avgoustiniatos ES, Firpo MT, Graham ML, Janecek J, Eberly LE, Garwood M, Putnam CW, Papas KK. Einstein SA, et al. Among authors: papas kk. Front Transplant. 2023 Nov 17;2:1257029. doi: 10.3389/frtra.2023.1257029. eCollection 2023. Front Transplant. 2023. PMID: 38993891 Free PMC article.
216 results