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A relationship between the aldosterone-mineralocorticoid receptor pathway and alcohol drinking: preliminary translational findings across rats, monkeys and humans.
Aoun EG, Jimenez VA, Vendruscolo LF, Walter NAR, Barbier E, Ferrulli A, Haass-Koffler CL, Darakjian P, Lee MR, Addolorato G, Heilig M, Hitzemann R, Koob GF, Grant KA, Leggio L. Aoun EG, et al. Among authors: vendruscolo lf. Mol Psychiatry. 2018 Jun;23(6):1466-1473. doi: 10.1038/mp.2017.97. Epub 2017 May 2. Mol Psychiatry. 2018. PMID: 28461696 Free PMC article.
Corticosteroid sensitization drives opioid addiction.
Carmack SA, Vendruscolo JCM, Adrienne McGinn M, Miranda-Barrientos J, Repunte-Canonigo V, Bosse GD, Mercatelli D, Giorgi FM, Fu Y, Hinrich AJ, Jodelka FM, Ling K, Messing RO, Peterson RT, Rigo F, Edwards S, Sanna PP, Morales M, Hastings ML, Koob GF, Vendruscolo LF. Carmack SA, et al. Among authors: vendruscolo lf, vendruscolo jcm. Mol Psychiatry. 2022 May;27(5):2492-2501. doi: 10.1038/s41380-022-01501-1. Epub 2022 Mar 16. Mol Psychiatry. 2022. PMID: 35296810 Free PMC article.
Spironolactone as a potential new pharmacotherapy for alcohol use disorder: convergent evidence from rodent and human studies.
Farokhnia M, Rentsch CT, Chuong V, McGinn MA, Elvig SK, Douglass EA, Gonzalez LA, Sanfilippo JE, Marchette RCN, Tunstall BJ, Fiellin DA, Koob GF, Justice AC, Leggio L, Vendruscolo LF. Farokhnia M, et al. Among authors: vendruscolo lf. Mol Psychiatry. 2022 Nov;27(11):4642-4652. doi: 10.1038/s41380-022-01736-y. Epub 2022 Sep 20. Mol Psychiatry. 2022. PMID: 36123420 Free PMC article.
Sex, strain, and estrous cycle influences on alcohol drinking in rats.
Priddy BM, Carmack SA, Thomas LC, Vendruscolo JC, Koob GF, Vendruscolo LF. Priddy BM, et al. Among authors: vendruscolo lf, vendruscolo jc. Pharmacol Biochem Behav. 2017 Jan;152:61-67. doi: 10.1016/j.pbb.2016.08.001. Epub 2016 Aug 4. Pharmacol Biochem Behav. 2017. PMID: 27498303 Free PMC article.
Methylomic profiling and replication implicates deregulation of PCSK9 in alcohol use disorder.
Lohoff FW, Sorcher JL, Rosen AD, Mauro KL, Fanelli RR, Momenan R, Hodgkinson CA, Vendruscolo LF, Koob GF, Schwandt M, George DT, Jones IS, Holmes A, Zhou Z, Xu MJ, Gao B, Sun H, Phillips MJ, Muench C, Kaminsky ZA. Lohoff FW, et al. Among authors: vendruscolo lf. Mol Psychiatry. 2018 Sep;23(9):1900-1910. doi: 10.1038/mp.2017.168. Epub 2017 Aug 29. Mol Psychiatry. 2018. PMID: 28848234 Free PMC article.
Ghrelin receptor deletion reduces binge-like alcohol drinking in rats.
Zallar LJ, Beurmann S, Tunstall BJ, Fraser CM, Koob GF, Vendruscolo LF, Leggio L. Zallar LJ, et al. Among authors: vendruscolo lf. J Neuroendocrinol. 2019 Jul;31(7):e12663. doi: 10.1111/jne.12663. Epub 2019 Jan 16. J Neuroendocrinol. 2019. PMID: 30456835
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