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An informatic framework for decoding protein complexes by top-down mass spectrometry.
Skinner OS, Havugimana PC, Haverland NA, Fornelli L, Early BP, Greer JB, Fellers RT, Durbin KR, Do Vale LH, Melani RD, Seckler HS, Nelp MT, Belov ME, Horning SR, Makarov AA, LeDuc RD, Bandarian V, Compton PD, Kelleher NL. Skinner OS, et al. Among authors: durbin kr. Nat Methods. 2016 Mar;13(3):237-40. doi: 10.1038/nmeth.3731. Epub 2016 Jan 18. Nat Methods. 2016. PMID: 26780093 Free PMC article.
Accurate Sequence Analysis of a Monoclonal Antibody by Top-Down and Middle-Down Orbitrap Mass Spectrometry Applying Multiple Ion Activation Techniques.
Fornelli L, Srzentić K, Huguet R, Mullen C, Sharma S, Zabrouskov V, Fellers RT, Durbin KR, Compton PD, Kelleher NL. Fornelli L, et al. Among authors: durbin kr. Anal Chem. 2018 Jul 17;90(14):8421-8429. doi: 10.1021/acs.analchem.8b00984. Epub 2018 Jun 28. Anal Chem. 2018. PMID: 29894161 Free PMC article.
STORI Plots Enable Accurate Tracking of Individual Ion Signals.
Kafader JO, Beu SC, Early BP, Melani RD, Durbin KR, Zabrouskov V, Makarov AA, Maze JT, Shinholt DL, Yip PF, Kelleher NL, Compton PD, Senko MW. Kafader JO, et al. Among authors: durbin kr. J Am Soc Mass Spectrom. 2019 Nov;30(11):2200-2203. doi: 10.1007/s13361-019-02309-0. Epub 2019 Sep 11. J Am Soc Mass Spectrom. 2019. PMID: 31512223 Free PMC article.
Thorough Performance Evaluation of 213 nm Ultraviolet Photodissociation for Top-down Proteomics.
Fornelli L, Srzentić K, Toby TK, Doubleday PF, Huguet R, Mullen C, Melani RD, Dos Santos Seckler H, DeHart CJ, Weisbrod CR, Durbin KR, Greer JB, Early BP, Fellers RT, Zabrouskov V, Thomas PM, Compton PD, Kelleher NL. Fornelli L, et al. Among authors: durbin kr. Mol Cell Proteomics. 2020 Feb;19(2):405-420. doi: 10.1074/mcp.TIR119.001638. Epub 2019 Dec 30. Mol Cell Proteomics. 2020. PMID: 31888965 Free PMC article.
Multiplexed mass spectrometry of individual ions improves measurement of proteoforms and their complexes.
Kafader JO, Melani RD, Durbin KR, Ikwuagwu B, Early BP, Fellers RT, Beu SC, Zabrouskov V, Makarov AA, Maze JT, Shinholt DL, Yip PF, Tullman-Ercek D, Senko MW, Compton PD, Kelleher NL. Kafader JO, et al. Among authors: durbin kr. Nat Methods. 2020 Apr;17(4):391-394. doi: 10.1038/s41592-020-0764-5. Epub 2020 Mar 2. Nat Methods. 2020. PMID: 32123391 Free PMC article.
52 results