Chen Y - Search Results

1

Discovery and Evaluation of TLR-Targeted Immune Agonists.

Chernyak N, Bhagwat B, Naravula S, Chen Y, Solban N, Zhang F, Kofman E, Raoufi F, Dang X, Bao J, Tomazela D, Baily M, Geierstanger B, Flygare JA, Han JH, Willingham A, Seganish WM. Chernyak N, et al. Among authors: chen y. J Med Chem. 2024 Sep 26;67(18):16222-16234. doi: 10.1021/acs.jmedchem.4c00804. Epub 2024 Sep 5. J Med Chem. 2024. PMID: 39235949

2

Discovery of 4-benzylpiperazinequinoline BChE inhibitor that suppresses neuroinflammation for the treatment of Alzheimer's disease.

Chen Y, Zhang W, Li Q, Xie H, Xing S, Lu X, Lyu W, Xiong B, Wang Y, Qu W, Liu W, Chi H, Zhang X, Feng F, Sun H. Chen Y, et al. Eur J Med Chem. 2024 Jun 5;272:116463. doi: 10.1016/j.ejmech.2024.116463. Epub 2024 Apr 30. Eur J Med Chem. 2024. PMID: 38704944

3

Inhibition of the hERG potassium ion channel by different non-nucleoside human cytomegalovirus polymerase antiviral inhibitor series and the exploration of variations on a pyrroloquinoline core to reduce cardiotoxicity potential.

Srinivas Kandadai A, Bai B, Rahim M, Lin F, Gu Z, Qi X, Zhang X, Dong H, Chen Y, Shen J, Nieman JA. Srinivas Kandadai A, et al. Among authors: chen y. Bioorg Med Chem. 2023 May 1;85:117276. doi: 10.1016/j.bmc.2023.117276. Epub 2023 Apr 5. Bioorg Med Chem. 2023. PMID: 37037115

4

Novel sulfonyl-substituted tetrandrine derivatives for colon cancer treatment by inducing mitochondrial apoptosis and inhibiting PI3K/AKT/mTOR pathway.

Ling J, Li X, Wang M, Zhang C, Liu Y, Zhang X, Liu C, Ren Q, Zeng Y, Wang C, Chen Y, Sun C, Chen H, Zuo Y, Cao X, Deng Y, Ren B, Li D, Lu J. Ling J, et al. Among authors: chen h, chen y. Bioorg Chem. 2024 Feb;143:107069. doi: 10.1016/j.bioorg.2023.107069. Epub 2023 Dec 29. Bioorg Chem. 2024. PMID: 38160477

5

Ren-Shen-Bu-Qi decoction alleviates exercise fatigue through activating PI3K/AKT/Nrf2 pathway in mice.

Chen Y, Gao T, Bai J, Zhang W, Zhou Y, Zhao R, Deng Y, Liu X, Huang Z, Wang S, Shen C, Liu S, Guo J. Chen Y, et al. Chin Med. 2024 Nov 5;19(1):154. doi: 10.1186/s13020-024-01027-4. Chin Med. 2024. PMID: 39501343

6

Challenges and strategies toward oncolytic virotherapy for leptomeningeal metastasis.

Zhao JL, Lin BL, Luo C, Yi YL, Huang P, Chen Y, Zhao S, Huang ZJ, Ma XY, Huang L. Zhao JL, et al. Among authors: chen y. J Transl Med. 2024 Nov 5;22(1):1000. doi: 10.1186/s12967-024-05794-4. J Transl Med. 2024. PMID: 39501324 Review.

7

Systematic multiomics analysis and in vitro experiments suggest that ITGA5 could serve as a promising therapeutic target for ccRCC.

Che X, Tian X, Wang Z, Zhu S, Ye S, Wang Y, Chen Y, Huang Y, Anwaier A, Yao P, Chen Y, Wu K, Liu Y, Xu W, Zhang H, Ye D. Che X, et al. Among authors: chen y. Cancer Cell Int. 2024 Nov 5;24(1):363. doi: 10.1186/s12935-024-03546-4. Cancer Cell Int. 2024. PMID: 39501306

8

Fabrication of apigenin and adenosine-loaded nanoparticles against doxorubicin-induced myocardial infarction by reducing inflammation and oxidative stress.

Li R, Xu A, Chen Y, Li Y, Fu R, Jiang W, Li X. Li R, et al. Among authors: chen y. BMC Biotechnol. 2024 Nov 5;24(1):87. doi: 10.1186/s12896-024-00912-y. BMC Biotechnol. 2024. PMID: 39501266

9

Conjunctival squamous metaplasia on amniotic membrane in Stevens-Johnson syndrome: a case report.

Chen YK, Chi CL, Lai CH, Wu PL. Chen YK, et al. BMC Ophthalmol. 2024 Nov 5;24(1):484. doi: 10.1186/s12886-024-03700-6. BMC Ophthalmol. 2024. PMID: 39501188

10

Mutation spectrum and genotype-phenotype correlation of pediatric patients with methylmalonic acidemia.

Lu F, Zhang B, Yang Y, Shi Y, Zheng F, Zhou Q, Chen Y, Zhou L, Yu B. Lu F, et al. Among authors: chen y. Pediatr Res. 2024 Nov 5. doi: 10.1038/s41390-024-03687-2. Online ahead of print. Pediatr Res. 2024. PMID: 39501060

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