Flint DB - Search Results

1

ATR inhibition radiosensitizes cells through augmented DNA damage and G2 cell cycle arrest abrogation.

Bright SJ, Manandhar M, Flint DB, Kolachina R, Ben Kacem M, Martinus DK, Turner BX, Qureshi I, McFadden CH, Marinello PC, Shaitelman SF, Sawakuchi GO. Bright SJ, et al. Among authors: flint db. JCI Insight. 2024 Oct 8;9(19):e179599. doi: 10.1172/jci.insight.179599. JCI Insight. 2024. PMID: 39235982 Free PMC article.

2

Time-Lapse Monitoring of DNA Damage Colocalized With Particle Tracks in Single Living Cells.

McFadden CH, Hallacy TM, Flint DB, Granville DA, Asaithamby A, Sahoo N, Akselrod MS, Sawakuchi GO. McFadden CH, et al. Among authors: flint db. Int J Radiat Oncol Biol Phys. 2016 Sep 1;96(1):221-7. doi: 10.1016/j.ijrobp.2016.04.007. Epub 2016 Apr 16. Int J Radiat Oncol Biol Phys. 2016. PMID: 27511858

3

Nonhomologous End Joining Is More Important Than Proton Linear Energy Transfer in Dictating Cell Death.

Bright SJ, Flint DB, Chakraborty S, McFadden CH, Yoon DS, Bronk L, Titt U, Mohan R, Grosshans DR, Sumazin P, Shaitelman SF, Asaithamby A, Sawakuchi GO. Bright SJ, et al. Among authors: flint db. Int J Radiat Oncol Biol Phys. 2019 Dec 1;105(5):1119-1125. doi: 10.1016/j.ijrobp.2019.08.011. Epub 2019 Aug 16. Int J Radiat Oncol Biol Phys. 2019. PMID: 31425731 Free PMC article.

4

Isolation of time-dependent DNA damage induced by energetic carbon ions and their fragments using fluorescent nuclear track detectors.

McFadden CH, Rahmanian S, Flint DB, Bright SJ, Yoon DS, O'Brien DJ, Asaithamby A, Abdollahi A, Greilich S, Sawakuchi GO. McFadden CH, et al. Among authors: flint db. Med Phys. 2020 Jan;47(1):272-281. doi: 10.1002/mp.13897. Epub 2019 Nov 19. Med Phys. 2020. PMID: 31677156

5

Cell lines of the same anatomic site and histologic type show large variability in intrinsic radiosensitivity and relative biological effectiveness to protons and carbon ions.

Flint DB, Bright SJ, McFadden CH, Konishi T, Ohsawa D, Turner B, Lin SH, Grosshans DR, Chiu HS, Sumazin P, Shaitelman SF, Sawakuchi GO. Flint DB, et al. Med Phys. 2021 Jun;48(6):3243-3261. doi: 10.1002/mp.14878. Epub 2021 May 9. Med Phys. 2021. PMID: 33837540

6

Effect of boron compounds on the biological effectiveness of proton therapy.

Manandhar M, Bright SJ, Flint DB, Martinus DKJ, Kolachina RV, Ben Kacem M, Titt U, Martin TJ, Lee CL, Morrison K, Shaitelman SF, Sawakuchi GO. Manandhar M, et al. Among authors: flint db. Med Phys. 2022 Sep;49(9):6098-6109. doi: 10.1002/mp.15824. Epub 2022 Jul 6. Med Phys. 2022. PMID: 35754208

7

An empirical model of proton RBE based on the linear correlation between x-ray and proton radiosensitivity.

Flint DB, Ruff CE, Bright SJ, Yepes P, Wang Q, Manandhar M, Ben Kacem M, Turner BX, Martinus DKJ, Shaitelman SF, Sawakuchi GO. Flint DB, et al. Med Phys. 2022 Sep;49(9):6221-6236. doi: 10.1002/mp.15850. Epub 2022 Jul 28. Med Phys. 2022. PMID: 35831779 Free PMC article.

8

Targeted Inhibition of DNA-PKcs, ATM, ATR, PARP, and Rad51 Modulate Response to X Rays and Protons.

Bright SJ, Flint DB, Martinus DKJ, Turner BX, Manandhar M, Ben Kacem M, McFadden CH, Yap TA, Shaitelman SF, Sawakuchi GO. Bright SJ, et al. Among authors: flint db. Radiat Res. 2022 Oct 1;198(4):336-346. doi: 10.1667/RADE-22-00040.1. Radiat Res. 2022. PMID: 35939823 Free PMC article.

9

An empirical model of carbon-ion relative biological effectiveness based on the linear correlation between radiosensitivity to photons and carbon ions.

Flint DB, Bright SJ, McFadden C, Konishi T, Martinus DKJ, Manandhar M, Ben Kacem M, Bronk L, Sawakuchi GO. Flint DB, et al. Phys Med Biol. 2024 Dec 10;69(24):245011. doi: 10.1088/1361-6560/ad918e. Phys Med Biol. 2024. PMID: 39530708 Free PMC article.

10

PARP inhibition radiosensitizes BRCA1 wildtype and mutated breast cancer to proton therapy.

Ben Kacem M, Bright SJ, Moran E, Flint DB, Martinus DKJ, Turner BX, Qureshi I, Kolachina R, Manandhar M, Marinello PC, Shaitelman SF, Sawakuchi GO. Ben Kacem M, et al. Among authors: flint db. Sci Rep. 2024 Dec 28;14(1):30897. doi: 10.1038/s41598-024-81914-w. Sci Rep. 2024. PMID: 39730675 Free PMC article.

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