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Cancer-associated fibroblasts confer ALK inhibitor resistance in EML4-ALK -driven lung cancer via concurrent integrin and MET signaling.
Hu Q, Remsing Rix LL, Desai B, Miroshnychenko D, Li X, Welsh EA, Fang B, Wright GM, Chaudhary N, Kroeger JL, Doebele RC, Koomen JM, Haura EB, Marusyk A, Rix U. Hu Q, et al. Among authors: rix u. bioRxiv [Preprint]. 2024 Aug 28:2024.08.27.609975. doi: 10.1101/2024.08.27.609975. bioRxiv. 2024. PMID: 39253447 Free PMC article. Preprint.
IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells.
Remsing Rix LL, Sumi NJ, Hu Q, Desai B, Bryant AT, Li X, Welsh EA, Fang B, Kinose F, Kuenzi BM, Chen YA, Antonia SJ, Lovly CM, Koomen JM, Haura EB, Marusyk A, Rix U. Remsing Rix LL, et al. Among authors: rix u. Sci Signal. 2022 Aug 16;15(747):eabj5879. doi: 10.1126/scisignal.abj5879. Epub 2022 Aug 16. Sci Signal. 2022. PMID: 35973030 Free PMC article.
Dissection of TBK1 signaling via phosphoproteomics in lung cancer cells.
Kim JY, Welsh EA, Oguz U, Fang B, Bai Y, Kinose F, Bronk C, Remsing Rix LL, Beg AA, Rix U, Eschrich SA, Koomen JM, Haura EB. Kim JY, et al. Among authors: rix u. Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12414-9. doi: 10.1073/pnas.1220674110. Epub 2013 Jul 8. Proc Natl Acad Sci U S A. 2013. PMID: 23836654 Free PMC article.
Chemical Proteomics with Novel Fully Functionalized Fragments and Stringent Target Prioritization Identifies the Glutathione-Dependent Isomerase GSTZ1 as a Lung Cancer Target.
Liao Y, Chin Chan S, Welsh EA, Fang B, Sun L, Schönbrunn E, Koomen JM, Duckett DR, Haura EB, Monastyrskyi A, Rix U. Liao Y, et al. Among authors: rix u. ACS Chem Biol. 2023 Feb 17;18(2):251-264. doi: 10.1021/acschembio.2c00587. Epub 2023 Jan 11. ACS Chem Biol. 2023. PMID: 36630201
88 results