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Page 1
Serially quantifying TERT rearrangement breakpoints in circulating tumor DNA enables minimal residual disease monitoring in patients with neuroblastoma.
Hollander JF, Szymansky A, Wünschel J, Astrahantseff K, Rosswog C, Thorwarth A, Thole-Kliesch TM, Chamorro Gonzalez R, Hundsdörfer P, Hauptmann K, Schmelz K, Gürgen D, Rogasch JMM, Henssen AG, Fischer M, Schulte JH, Eckert C, Eggert A, Lodrini M, Deubzer HE. Hollander JF, et al. Among authors: szymansky a. Cancer Res Commun. 2025 Jan 6. doi: 10.1158/2767-9764.CRC-24-0569. Online ahead of print. Cancer Res Commun. 2025. PMID: 39760332 Free article.
Targeting KDM1A in Neuroblastoma with NCL-1 Induces a Less Aggressive Phenotype and Suppresses Angiogenesis.
Sprüssel A, Suzuki T, Miyata N, Astrahantseff K, Szymansky A, Toedling J, Thole-Kliesch TM, Ballagee A, Lodrini M, Künkele A, Truss M, Heukamp LC, Mathia S, Hertwig F, Rosenberger C, Eggert A, Deubzer HE, Schulte JH. Sprüssel A, et al. Among authors: szymansky a. J Clin Med. 2024 Oct 12;13(20):6081. doi: 10.3390/jcm13206081. J Clin Med. 2024. PMID: 39458030 Free PMC article.
Mutational topography reflects clinical neuroblastoma heterogeneity.
Rodriguez-Fos E, Planas-Fèlix M, Burkert M, Puiggròs M, Toedling J, Thiessen N, Blanc E, Szymansky A, Hertwig F, Ishaque N, Beule D, Torrents D, Eggert A, Koche RP, Schwarz RF, Haase K, Schulte JH, Henssen AG. Rodriguez-Fos E, et al. Among authors: szymansky a. Cell Genom. 2023 Sep 7;3(10):100402. doi: 10.1016/j.xgen.2023.100402. eCollection 2023 Oct 11. Cell Genom. 2023. PMID: 37868040 Free PMC article.
Defining the landscape of circular RNAs in neuroblastoma unveils a global suppressive function of MYCN.
Fuchs S, Danßmann C, Klironomos F, Winkler A, Fallmann J, Kruetzfeldt LM, Szymansky A, Naderi J, Bernhart SH, Grunewald L, Helmsauer K, Rodriguez-Fos E, Kirchner M, Mertins P, Astrahantseff K, Suenkel C, Toedling J, Meggetto F, Remke M, Stadler PF, Hundsdoerfer P, Deubzer HE, Künkele A, Lang P, Fuchs J, Henssen AG, Eggert A, Rajewsky N, Hertwig F, Schulte JH. Fuchs S, et al. Among authors: szymansky a. Nat Commun. 2023 Jul 4;14(1):3936. doi: 10.1038/s41467-023-38747-4. Nat Commun. 2023. PMID: 37402719 Free PMC article.
Targeted Analysis of Cell-free Circulating Tumor DNA is Suitable for Early Relapse and Actionable Target Detection in Patients with Neuroblastoma.
Lodrini M, Graef J, Thole-Kliesch TM, Astrahantseff K, Sprüssel A, Grimaldi M, Peitz C, Linke RB, Hollander JF, Lankes E, Künkele A, Oevermann L, Schwabe G, Fuchs J, Szymansky A, Schulte JH, Hundsdörfer P, Eckert C, Amthauer H, Eggert A, Deubzer HE. Lodrini M, et al. Among authors: szymansky a. Clin Cancer Res. 2022 May 2;28(9):1809-1820. doi: 10.1158/1078-0432.CCR-21-3716. Clin Cancer Res. 2022. PMID: 35247920
Spatial and temporal intratumour heterogeneity has potential consequences for single biopsy-based neuroblastoma treatment decisions.
Schmelz K, Toedling J, Huska M, Cwikla MC, Kruetzfeldt LM, Proba J, Ambros PF, Ambros IM, Boral S, Lodrini M, Chen CY, Burkert M, Guergen D, Szymansky A, Astrahantseff K, Kuenkele A, Haase K, Fischer M, Deubzer HE, Hertwig F, Hundsdoerfer P, Henssen AG, Schwarz RF, Schulte JH, Eggert A. Schmelz K, et al. Among authors: szymansky a. Nat Commun. 2021 Nov 23;12(1):6804. doi: 10.1038/s41467-021-26870-z. Nat Commun. 2021. PMID: 34815394 Free PMC article.
Neuroblastoma Risk Assessment and Treatment Stratification with Hybrid Capture-Based Panel Sequencing.
Szymansky A, Kruetzfeldt LM, Heukamp LC, Hertwig F, Theissen J, Deubzer HE, Willing EM, Menon R, Fuchs S, Thole T, Schulte S, Schmelz K, Künkele A, Lang P, Fuchs J, Eggert A, Eckert C, Fischer M, Henssen AG, Rodriguez-Fos E, Schulte JH. Szymansky A, et al. J Pers Med. 2021 Jul 22;11(8):691. doi: 10.3390/jpm11080691. J Pers Med. 2021. PMID: 34442335 Free PMC article.
Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma.
Helmsauer K, Valieva ME, Ali S, Chamorro González R, Schöpflin R, Röefzaad C, Bei Y, Dorado Garcia H, Rodriguez-Fos E, Puiggròs M, Kasack K, Haase K, Keskeny C, Chen CY, Kuschel LP, Euskirchen P, Heinrich V, Robson MI, Rosswog C, Toedling J, Szymansky A, Hertwig F, Fischer M, Torrents D, Eggert A, Schulte JH, Mundlos S, Henssen AG, Koche RP. Helmsauer K, et al. Among authors: szymansky a. Nat Commun. 2020 Nov 16;11(1):5823. doi: 10.1038/s41467-020-19452-y. Nat Commun. 2020. PMID: 33199677 Free PMC article.
16 results