Smith BC - Search Results

1

Inhibition of Sirtuin Deacylase Activity by Peroxynitrite.

Bohl K, Wynia-Smith SL, Jones Lipinski RA, Smith BC. Bohl K, et al. Among authors: smith bc. Biochemistry. 2024 Oct 1;63(19):2463-2476. doi: 10.1021/acs.biochem.4c00257. Epub 2024 Sep 10. Biochemistry. 2024. PMID: 39256054

2

Mechanism-based inhibition of Sir2 deacetylases by thioacetyl-lysine peptide.

Smith BC, Denu JM. Smith BC, et al. Biochemistry. 2007 Dec 18;46(50):14478-86. doi: 10.1021/bi7013294. Epub 2007 Nov 21. Biochemistry. 2007. PMID: 18027980

3

Truncating mutation in the nitric oxide synthase 1 gene is associated with infantile achalasia.

Shteyer E, Edvardson S, Wynia-Smith SL, Pierri CL, Zangen T, Hashavya S, Begin M, Yaacov B, Cinamon Y, Koplewitz BZ, Vromen A, Elpeleg O, Smith BC. Shteyer E, et al. Among authors: smith bc. Gastroenterology. 2015 Mar;148(3):533-536.e4. doi: 10.1053/j.gastro.2014.11.044. Epub 2014 Dec 3. Gastroenterology. 2015. PMID: 25479138

4

Chemoproteomic Strategy to Quantitatively Monitor Transnitrosation Uncovers Functionally Relevant S-Nitrosation Sites on Cathepsin D and HADH2.

Zhou Y, Wynia-Smith SL, Couvertier SM, Kalous KS, Marletta MA, Smith BC, Weerapana E. Zhou Y, et al. Among authors: smith bc. Cell Chem Biol. 2016 Jun 23;23(6):727-37. doi: 10.1016/j.chembiol.2016.05.008. Epub 2016 Jun 9. Cell Chem Biol. 2016. PMID: 27291402 Free PMC article.

5

Nitrosothiol formation and S-nitrosation signaling through nitric oxide synthases.

Wynia-Smith SL, Smith BC. Wynia-Smith SL, et al. Among authors: smith bc. Nitric Oxide. 2017 Feb 28;63:52-60. doi: 10.1016/j.niox.2016.10.001. Epub 2016 Oct 5. Nitric Oxide. 2017. PMID: 27720836 Review.

6

Mechanism of Sirt1 NAD+-dependent Protein Deacetylase Inhibition by Cysteine S-Nitrosation.

Kalous KS, Wynia-Smith SL, Olp MD, Smith BC. Kalous KS, et al. Among authors: smith bc. J Biol Chem. 2016 Dec 2;291(49):25398-25410. doi: 10.1074/jbc.M116.754655. Epub 2016 Oct 18. J Biol Chem. 2016. PMID: 27756843 Free PMC article.

7

Metabolically Derived Lysine Acylations and Neighboring Modifications Tune the Binding of the BET Bromodomains to Histone H4.

Olp MD, Zhu N, Smith BC. Olp MD, et al. Among authors: smith bc. Biochemistry. 2017 Oct 17;56(41):5485-5495. doi: 10.1021/acs.biochem.7b00595. Epub 2017 Oct 5. Biochemistry. 2017. PMID: 28945351 Free PMC article.

8

Comparative and integrative metabolomics reveal that S-nitrosation inhibits physiologically relevant metabolic enzymes.

Bruegger JJ, Smith BC, Wynia-Smith SL, Marletta MA. Bruegger JJ, et al. Among authors: smith bc. J Biol Chem. 2018 Apr 27;293(17):6282-6296. doi: 10.1074/jbc.M117.817700. Epub 2018 Feb 26. J Biol Chem. 2018. PMID: 29483187 Free PMC article.

9

Covalent-Fragment Screening of BRD4 Identifies a Ligandable Site Orthogonal to the Acetyl-Lysine Binding Sites.

Olp MD, Sprague DJ, Goetz CJ, Kathman SG, Wynia-Smith SL, Shishodia S, Summers SB, Xu Z, Statsyuk AV, Smith BC. Olp MD, et al. Among authors: smith bc. ACS Chem Biol. 2020 Apr 17;15(4):1036-1049. doi: 10.1021/acschembio.0c00058. Epub 2020 Mar 23. ACS Chem Biol. 2020. PMID: 32149490 Free PMC article.

10

Human sirtuins are differentially sensitive to inhibition by nitrosating agents and other cysteine oxidants.

Kalous KS, Wynia-Smith SL, Summers SB, Smith BC. Kalous KS, et al. Among authors: smith bc. J Biol Chem. 2020 Jun 19;295(25):8524-8536. doi: 10.1074/jbc.RA119.011988. Epub 2020 May 5. J Biol Chem. 2020. PMID: 32371394 Free PMC article.

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