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A spatially resolved single-cell lung atlas integrated with clinical and blood signatures distinguishes COVID-19 disease trajectories.
Da Silva Filho J, Herder V, Gibbins MP, Dos Reis MF, Melo GC, Haley MJ, Judice CC, Val FFA, Borba M, Tavella TA, de Sousa Sampaio V, Attipa C, McMonagle F, Wright D, de Lacerda MVG, Costa FTM, Couper KN, Marcelo Monteiro W, de Lima Ferreira LC, Moxon CA, Palmarini M, Marti M. Da Silva Filho J, et al. Among authors: palmarini m. Sci Transl Med. 2024 Sep 11;16(764):eadk9149. doi: 10.1126/scitranslmed.adk9149. Epub 2024 Sep 11. Sci Transl Med. 2024. PMID: 39259811
Schmallenberg virus pathogenesis, tropism and interaction with the innate immune system of the host.
Varela M, Schnettler E, Caporale M, Murgia C, Barry G, McFarlane M, McGregor E, Piras IM, Shaw A, Lamm C, Janowicz A, Beer M, Glass M, Herder V, Hahn K, Baumgärtner W, Kohl A, Palmarini M. Varela M, et al. Among authors: palmarini m. PLoS Pathog. 2013 Jan;9(1):e1003133. doi: 10.1371/journal.ppat.1003133. Epub 2013 Jan 10. PLoS Pathog. 2013. PMID: 23326235 Free PMC article.
Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19.
Thwaites RS, Sanchez Sevilla Uruchurtu A, Siggins MK, Liew F, Russell CD, Moore SC, Fairfield C, Carter E, Abrams S, Short CE, Thaventhiran T, Bergstrom E, Gardener Z, Ascough S, Chiu C, Docherty AB, Hunt D, Crow YJ, Solomon T, Taylor GP, Turtle L, Harrison EM, Dunning J, Semple MG, Baillie JK, Openshaw PJ; ISARIC4C investigators. Thwaites RS, et al. Sci Immunol. 2021 Mar 10;6(57):eabg9873. doi: 10.1126/sciimmunol.abg9873. Sci Immunol. 2021. PMID: 33692097 Free PMC article.
A prenylated dsRNA sensor protects against severe COVID-19.
Wickenhagen A, Sugrue E, Lytras S, Kuchi S, Noerenberg M, Turnbull ML, Loney C, Herder V, Allan J, Jarmson I, Cameron-Ruiz N, Varjak M, Pinto RM, Lee JY, Iselin L, Palmalux N, Stewart DG, Swingler S, Greenwood EJD, Crozier TWM, Gu Q, Davies EL, Clohisey S, Wang B, Trindade Maranhão Costa F, Freire Santana M, de Lima Ferreira LC, Murphy L, Fawkes A, Meynert A, Grimes G; ISARIC4C Investigators; Da Silva Filho JL, Marti M, Hughes J, Stanton RJ, Wang ECY, Ho A, Davis I, Jarrett RF, Castello A, Robertson DL, Semple MG, Openshaw PJM, Palmarini M, Lehner PJ, Baillie JK, Rihn SJ, Wilson SJ. Wickenhagen A, et al. Among authors: palmarini m. Science. 2021 Oct 29;374(6567):eabj3624. doi: 10.1126/science.abj3624. Epub 2021 Oct 29. Science. 2021. PMID: 34581622 Free PMC article.
Phenotyping the virulence of SARS-CoV-2 variants in hamsters by digital pathology and machine learning.
Meehan GR, Herder V, Allan J, Huang X, Kerr K, Mendonca DC, Ilia G, Wright DW, Nomikou K, Gu Q, Molina Arias S, Hansmann F, Hardas A, Attipa C, De Lorenzo G, Cowton V, Upfold N, Palmalux N, Brown JC, Barclay WS, Filipe ADS, Furnon W, Patel AH, Palmarini M. Meehan GR, et al. Among authors: palmarini m. PLoS Pathog. 2023 Nov 7;19(11):e1011589. doi: 10.1371/journal.ppat.1011589. eCollection 2023 Nov. PLoS Pathog. 2023. PMID: 37934791 Free PMC article.
Spatially resolved single-cell atlas unveils a distinct cellular signature of fatal lung COVID-19 in a Malawian population.
Nyirenda J, Hardy OM, Silva Filho JD, Herder V, Attipa C, Ndovi C, Siwombo M, Namalima TR, Suwedi L, Ilia G, Nyasulu W, Ngulube T, Nyirenda D, Mvaya L, Phiri J, Chasweka D, Eneya C, Makwinja C, Phiri C, Ziwoya F, Tembo A, Makwangwala K, Khoswe S, Banda P, Morton B, Hilton O, Lawrence S, Dos Reis MF, Melo GC, de Lacerda MVG, Trindade Maranhão Costa F, Monteiro WM, Ferreira LCL, Johnson C, McGuinness D, Jambo K, Haley M, Kumwenda B, Palmarini M, Denno DM, Voskuijl W, Kamiza SB, Barnes KG, Couper K, Marti M, Otto TD, Moxon CA. Nyirenda J, et al. Among authors: palmarini m. Nat Med. 2024 Dec;30(12):3765-3777. doi: 10.1038/s41591-024-03354-3. Epub 2024 Nov 20. Nat Med. 2024. PMID: 39567718 Free PMC article.
Phenotypic evolution of SARS-CoV-2 spike during the COVID-19 pandemic.
Furnon W, Cowton VM, De Lorenzo G, Orton R, Herder V, Cantoni D, Ilia G, Mendonca DC, Kerr K, Allan J, Upfold N, Meehan GR, Bakshi S, Das UR, Molina Arias S, McElwee M, Little S, Logan N, Kwok K, Smollett K, Willett BJ, Da Silva Filipe A, Robertson DL, Grove J, Patel AH, Palmarini M. Furnon W, et al. Among authors: palmarini m. Nat Microbiol. 2025 Jan;10(1):77-93. doi: 10.1038/s41564-024-01878-5. Epub 2025 Jan 3. Nat Microbiol. 2025. PMID: 39753670 Free PMC article.
Skeletal muscle hypoplasia represents the only significant lesion in peripheral organs of ruminants infected with Schmallenberg virus during gestation.
Seehusen F, Hahn K, Herder V, Weigand M, Habierski A, Gerhauser I, Wohlsein P, Peters M, Varela M, Palmarini M, Baumgärtner W. Seehusen F, et al. Among authors: palmarini m. J Comp Pathol. 2014 Aug-Oct;151(2-3):148-52. doi: 10.1016/j.jcpa.2014.04.006. Epub 2014 Jun 26. J Comp Pathol. 2014. PMID: 24975894
201 results