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232 results

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Page 1
Novel N-(Heterocyclylphenyl)benzensulfonamide Sharing an Unreported Binding Site with T-Cell Factor 4 at the β-Catenin Armadillo Repeats Domain as an Anticancer Agent.
Nalli M, Di Magno L, Wen Y, Liu X, D'Ambrosio M, Puxeddu M, Parisi A, Sebastiani J, Sorato A, Coluccia A, Ripa S, Di Pastena F, Capelli D, Montanari R, Masci D, Urbani A, Naro C, Sette C, Orlando V, D'Angelo S, Biagioni S, Bigogno C, Dondio G, Pastore A, Stornaiuolo M, Canettieri G, Liu T, Silvestri R, La Regina G. Nalli M, et al. Among authors: sette c. ACS Pharmacol Transl Sci. 2023 Jul 3;6(7):1087-1103. doi: 10.1021/acsptsci.3c00092. eCollection 2023 Jul 14. ACS Pharmacol Transl Sci. 2023. PMID: 37470018 Free PMC article.
Enhancing sensitivity of triple-negative breast cancer to DNA-damaging therapy through chemical inhibition of the m6A methyltransferase METTL3.
Cesaro B, Iaiza A, Piscopo F, Tarullo M, Cesari E, Rotili D, Mai A, Diana A, Londero M, Del Giacco L, Masetti R, Di Leone A, Naro C, Masciarelli S, Fontemaggi G, Sette C, Fazi F, Fatica A. Cesaro B, et al. Among authors: sette c. Cancer Commun (Lond). 2024 Feb;44(2):282-286. doi: 10.1002/cac2.12509. Epub 2023 Dec 15. Cancer Commun (Lond). 2024. PMID: 38102821 Free PMC article. No abstract available.
An alternative splicing signature defines the basal-like phenotype and predicts worse clinical outcome in pancreatic cancer.
Ruta V, Naro C, Pieraccioli M, Leccese A, Archibugi L, Cesari E, Panzeri V, Allgöwer C, Arcidiacono PG, Falconi M, Carbone C, Tortora G, Borrelli F, Attili F, Spada C, Quero G, Alfieri S, Doglioni C, Kleger A, Capurso G, Sette C. Ruta V, et al. Among authors: sette c. Cell Rep Med. 2024 Feb 20;5(2):101411. doi: 10.1016/j.xcrm.2024.101411. Epub 2024 Feb 6. Cell Rep Med. 2024. PMID: 38325381 Free PMC article.
SAM68 directs STING signaling to apoptosis in macrophages.
van der Horst D, Kurmasheva N, Marqvorsen MHS, Assil S, Rahimic AHF, Kollmann CF, Silva da Costa L, Wu Q, Zhao J, Cesari E, Iversen MB, Ren F, Jensen TI, Narita R, Schack VR, Zhang BC, Bak RO, Sette C, Fenton RA, Mikkelsen JG, Paludan SR, Olagnier D. van der Horst D, et al. Among authors: sette c. Commun Biol. 2024 Mar 7;7(1):283. doi: 10.1038/s42003-024-05969-1. Commun Biol. 2024. PMID: 38454028 Free PMC article.
Development of N-(4-(1H-Imidazol-1-yl)phenyl)-4-chlorobenzenesulfonamide, a Novel Potent Inhibitor of β-Catenin with Enhanced Antitumor Activity and Metabolic Stability.
Puxeddu M, Ling L, Ripa S, D'Ambrosio M, Nalli M, Parisi A, Sciò P, Coluccia A, Granese A, Santelli M, Masci D, Cuřínová P, Naro C, Sette C, Pastore A, Stornaiuolo M, Bigogno C, Dondio G, Di Magno L, Canettieri G, Liu T, Silvestri R, La Regina G. Puxeddu M, et al. Among authors: sette c. J Med Chem. 2024 Nov 28;67(22):20298-20314. doi: 10.1021/acs.jmedchem.4c01708. Epub 2024 Nov 7. J Med Chem. 2024. PMID: 39508273
232 results