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Page 1
Intercellular nanotube-mediated mitochondrial transfer enhances T cell metabolic fitness and antitumor efficacy.
Baldwin JG, Heuser-Loy C, Saha T, Schelker RC, Slavkovic-Lukic D, Strieder N, Hernandez-Lopez I, Rana N, Barden M, Mastrogiovanni F, Martín-Santos A, Raimondi A, Brohawn P, Higgs BW, Gebhard C, Kapoor V, Telford WG, Gautam S, Xydia M, Beckhove P, Frischholz S, Schober K, Kontarakis Z, Corn JE, Iannacone M, Inverso D, Rehli M, Fioravanti J, Sengupta S, Gattinoni L. Baldwin JG, et al. Cell. 2024 Nov 14;187(23):6614-6630.e21. doi: 10.1016/j.cell.2024.08.029. Epub 2024 Sep 13. Cell. 2024. PMID: 39276774 Free article.
LIM-domain-only 4 (LMO4) enhances CD8+ T-cell stemness and tumor rejection by boosting IL-21-STAT3 signaling.
Schelker RC, Fioravanti J, Mastrogiovanni F, Baldwin JG, Rana N, Li P, Chen P, Vadász T, Spolski R, Heuser-Loy C, Slavkovic-Lukic D, Noronha P, Damiano G, Raccosta L, Maggioni D, Pullugula S, Lin JX, Oh J, Grandinetti P, Lecce M, Hesse L, Kocks E, Martín-Santos A, Gebhard C, Telford WG, Ji Y, Restifo NP, Russo V, Rehli M, Herr W, Leonard WJ, Gattinoni L. Schelker RC, et al. Among authors: baldwin jg. Signal Transduct Target Ther. 2024 Aug 9;9(1):199. doi: 10.1038/s41392-024-01915-z. Signal Transduct Target Ther. 2024. PMID: 39117617 Free PMC article.
Cancer cells hijack T-cell mitochondria.
Baldwin JG, Gattinoni L. Baldwin JG, et al. Nat Nanotechnol. 2022 Jan;17(1):3-4. doi: 10.1038/s41565-021-01006-y. Nat Nanotechnol. 2022. PMID: 34795442 No abstract available.
A humanized orthotopic tumor microenvironment alters the bone metastatic tropism of prostate cancer cells.
McGovern JA, Bock N, Shafiee A, Martine LC, Wagner F, Baldwin JG, Landgraf M, Lahr CA, Meinert C, Williams ED, Pollock PM, Denham J, Russell PJ, Risbridger GP, Clements JA, Loessner D, Holzapfel BM, Hutmacher DW. McGovern JA, et al. Among authors: baldwin jg. Commun Biol. 2021 Aug 30;4(1):1014. doi: 10.1038/s42003-021-02527-x. Commun Biol. 2021. PMID: 34462519 Free PMC article.
Humanization of bone and bone marrow in an orthotopic site reveals new potential therapeutic targets in osteosarcoma.
Wagner F, Holzapfel BM, McGovern JA, Shafiee A, Baldwin JG, Martine LC, Lahr CA, Wunner FM, Friis T, Bas O, Boxberg M, Prodinger PM, Shokoohmand A, Moi D, Mazzieri R, Loessner D, Hutmacher DW. Wagner F, et al. Among authors: baldwin jg. Biomaterials. 2018 Jul;171:230-246. doi: 10.1016/j.biomaterials.2018.04.030. Epub 2018 Apr 16. Biomaterials. 2018. PMID: 29705656
Biofabricated soft network composites for cartilage tissue engineering.
Bas O, De-Juan-Pardo EM, Meinert C, D'Angella D, Baldwin JG, Bray LJ, Wellard RM, Kollmannsberger S, Rank E, Werner C, Klein TJ, Catelas I, Hutmacher DW. Bas O, et al. Among authors: baldwin jg. Biofabrication. 2017 May 12;9(2):025014. doi: 10.1088/1758-5090/aa6b15. Biofabrication. 2017. PMID: 28374682
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